Information below is an extract from the APS publications database

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Sector: 23 GM/CA-XSD
Number of Records: 2099
Kevin S. Blake, Hirdesh Kumar, Anisha Loganathan, Emily E. Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P. Campbell, David D. Chong, Steven Angtuaco, Timothy A. Wencewicz, Niraj H. Tolia, Gautam Dantas, "Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes," Commun. Biol. 7, 336 (2024). DOI: 10.1038/s42003-024-06023-w

Vatsal Purohit, Calvin N. Steussy, Anthony R. Rosales, Chandra J. Critchelow, Tim Schmidt, Paul Helquist, Olaf Wiest, Andrew Mesecar, Aina E. Cohen, Cynthia V. Stauffacher, "pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography," Biophys. J. 123 (5), 622-637 (2024). DOI: 10.1016/j.bpj.2024.02.003

Dave L. Carlson, Mark Kowalewski, Khaldon Bodoor, Adam D. Lietzan, Philip F. Hughes, David Gooden, David R. Loiselle, David Alcorta, Zoey Dingman, Elizabeth A. Mueller, Irnov Irnov, Shannon Modla, Tim Chaya, Jeffrey Caplan, Monica Embers, Jennifer C. Miller, Christine Jacobs-Wagner, Matthew R. Redinbo, Neil Spector, Timothy A.J. Haystead, "Targeting Borrelia burgdorferi HtpG with a berserker molecule, a strategy for anti-microbial development," Cell Chem. Biol. 31 (3), 465-476 (2024). DOI: 10.1016/j.chembiol.2023.10.004

Franco K.K. Li, Liam J. Worrall, Robert T. Gale, Eric D. Brown, Natalie C.J. Strynadka, "Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance," Sci. Advances 10 (9), eadj3864 (2024). DOI: 10.1126/sciadv.adj3864

Anisa Ghosh, Kevin Delgado-Cunningham, Tomas Lopez, Kassidy Green, Carlos F. Arias, Rebecca M. DuBois, "Structure and antigenicity of the divergent human astrovirus VA1 capsid spike," PLoS Patho. 20 (2), e1012028 (2024). DOI: 10.1371/journal.ppat.1012028

Zhengrui Zhang, Hannah M. Rondon-Cordero, Chittaranjan Das, "Crystal structure of bacterial ubiquitin ADP-ribosyltransferase CteC reveals a substrate-recruiting insertion," J. Biol. Chem. 300 (2), 105604 (2024). DOI: 10.1016/j.jbc.2023.105604

Christian Nilewski, Sharada Labadie, Binqing Wei, Sushant Malhotra, Steven Do, Lewis Gazzard, Li Liu, Cheng Shao, Jeremy Murray, Yevgeniy Izrayelit, Amy Gustafson, Nicholas F. Endres, Fang Ma, Xin Ye, Jun Zou, Marie Evangelista, "Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors," ACS Med. Chem. Lett. 15 (1), 21-28 (2024). DOI: 10.1021/acsmedchemlett.3c00478

Mikoto Kiya, Shota Shiga, Peiwei Ding, Shohei Koide, Koki Makabe, "[beta]-Strand-mediated Domain-swapping in the Absence of Hydrophobic Core Repacking," J. Mol. Biol. 436 (2), 168405 (2024). DOI: 10.1016/j.jmb.2023.168405

Paul J. Caffrey, Brian E. Eckenroth, Brett W. Burkhart, Kelly M. Zatopek, Colleen M. McClung, Thomas J. Santangelo, Sylvie Doublié, Andrew F. Gardner, "Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold," J. Biol. Chem. 300 (1), 105503 (2024). DOI: 10.1016/j.jbc.2023.105503

Nicholas Lorig-Roach, Nina M. Harpell, Rebecca M. DuBois, "Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab," Sci. Rep. 14, 742 (2024). DOI: 10.1038/s41598-023-50262-6

Tingfeng Guo, Anthony M. Sperber, Inna V. Krieger, Yi Duan, Veronica R. Chemelewski, James C. Sacchettini, Jennifer K. Herman, "Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization," J. Bacteriol. 206 (1), e00202 (2024). DOI: 10.1128/jb.00202-23

Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K. O’Flaherty, Xiwen Jia, Talbot B. Stone, Lijun Zhou, Jack W. Szostak, "Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying," J. Am. Chem. Soc. 146 (6), 3861-3871 (2024). DOI: 10.1021/jacs.3c11158

Yueyi Chen, Amol Sonawane, Rajesh Manda, Ranjith Kumar Gadi, John J.G. Tesmer, Arun K. Ghosh, "Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes," Eur. J. Med. Chem. 264, 115931 (2024). DOI: 10.1016/j.ejmech.2023.115931

K.K. Crone, T. Jomori, F.S. Miller, J.A. Gralnick, M.H. Elias, M.F. Freeman, "RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin [alpha]-N-methylated peptide natural product," RSC Chem. Biol. 4 (10), 804-816 (2023). DOI: 10.1039/D3CB00093A

Nathan H. Murray, Christopher R.M. Asquith, Zixiang Fang, Michael P. East, Naomi Ptak, Robert W. Smith, James D. Vasta, Chad A. Zimprich, Cesear R. Corona, Matthew B. Robers, Gary L. Johnson, Craig A. Bingman, David J. Pagliarini, "Small-molecule inhibition of the archetypal UbiB protein COQ8," Nat. Chem. Biol. 19, 230-238 (2023). DOI: 10.1038/s41589-022-01168-3

Christopher J. Schulze, Kyle J. Seamon, Yulei Zhao, Yu C. Yang, Jim Cregg, Dongsung Kim, Aidan Tomlinson, Tiffany J. Choy, Zhican Wang, Ben Sang, Yasin Pourfarjam, Jessica Lucas, Antonio Cuevas-Navarro, Carlos Ayala-Santos, Alberto Vides, Chuanchuan Li, Abby Marquez, Mengqi Zhong, Vidyasiri Vemulapalli, Caroline Weller, Andrea Gould, Daniel M. Whalen, Anthony Salvador, Anthony Milin, Mae Saldajeno-Concar, Nuntana Dinglasan, Anqi Chen, Jim Evans, John E. Knox, Elena S. Koltun, Mallika Singh, Robert Nichols, David Wildes, Adrian L. Gill, Jacqueline A.M. Smith, Piro Lito, "Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS," Science 381 (6659), 794-799 (2023). DOI: 10.1126/science.adg9652

Deyi Zhang, Hailey M Harris, Jonathan Chen, Jen Judy, Gabriella James, Aileen Kelly, Joel McIntosh, Austin Tenn-McClellan, Eileen Ambing, Ying Siow Tan, Hao Lu, Stefan Gajewski, Matthew C Clifton, Stephanie Yung, Daniel W Robbins, Mehdi Pirooznia, Sigrid S Skånland, Erika Gaglione, Maissa Mhibik, Chingiz Underbayev, Inhye E Ahn, Clare Sun, Sarah E M Herman, Mark Noviski, Adrian Wiestner, "NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts," Blood 141 (13), 1584-1596 (2023). DOI: 10.1182/blood.2022016934

Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean-Philippe Julien, Elena A Levashina, Hedda Wardemann, "Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies," EMBO Mol. Med. 2023, e17454 (2023). DOI: 10.15252/emmm.202317454

Jing-Xiang Wang, Avery C. Vilbert, Chang Cui, Evan N. Mirts, Lucas H. Williams, Wantae Kim, Y. Jessie Zhang, Yi Lu, "Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations," Angew. Chem. Int. Ed. 62 (52), e202314019 (2023). DOI: 10.1002/anie.202314019

Brian E. Eckenroth, Joshua D. Bumgarner, Olivia Matsumoto-Elliott, Sheila S. David, Sylvie Doublié, "Structural and biochemical insights into NEIL2's preference for abasic sites," Nucleic Acids Res. 51 (22), 12508-12521 (2023). DOI: 10.1093/nar/gkad1075

Kendra A. Ireland, Chase M. Kayrouz, Jonathan Huang, Mohammad R. Seyedsayamdost, Katherine M. Davis, "Structural Characterization and Ligand-Induced Conformational Changes of SenB, a Se-Glycosyltransferase Involved in Selenoneine Biosynthesis," Biochemistry-US 62 (23), 3337-3342 (2023). DOI: 10.1021/acs.biochem.3c00452

Sarah Lanning, Natalie Pedicino, Danielle J. Haley, Samuel Hernandez, Valerie Cortez, Rebecca M. DuBois, "Structure and immunogenicity of the murine astrovirus capsid spike," J. Gen. Virol. 104 (11), 001913 (2023). DOI: 10.1099/jgv.0.001913

Brianna M. Busscher, Henock B. Befekadu, Zhonghua Liu, Tsan Sam Xiao, "SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence," Viruses-Basel 15 (11), 2229 (2023). DOI: 10.3390/v15112229

Elaine Thai, Rajagopal Murugan, Špela Binter, Clare Burn Aschner, Katherine Prieto, Audrey Kassardjian, Anna S. Obraztsova, Ryu Won Kang, Yevel Flores-Garcia, Shamika Mathis-Torres, Kan Li, Gillian Q. Horn, Richard H.C. Huntwork, Judith M. Bolscher, Marloes H.C. de Bruijni, Robert Sauerwein, S. Moses Dennison, Georgia D. Tomaras, Fidel Zavala, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien, "Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein," Cell Reports 42 (11), 113330 (2023). DOI: 10.1016/j.celrep.2023.113330

Amanda L. Graboski, Mark E. Kowalewski, Joshua B. Simpson, Xufeng Cao, Mary Ha, Jianan Zhang, William G. Walton, Daniel P. Flaherty, Matthew R. Redinbo, "Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate," Cell Chem. Biol. 30 (11), 1402-1413 (2023). DOI: 10.1016/j.chembiol.2023.07.015

Catherine A. Wilhelm, Leena Mallik, Abigail L. Kelly, Shayna Brotzman, Johnny Mendoza, Anna G. Anders, Suada Leskaj, Carmen Castillo, Brandon T. Ruotolo, Michael A. Cianfrocco, Markos Koutmos, "Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P," J. Biol. Chem. 299 (11), 105327 (2023). DOI: 10.1016/j.jbc.2023.105327

David Yin-wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti, "Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states," eLIFE J. 12, RP89489 (2023). DOI: 10.7554/eLife.89489

Arjun K. Mishra, Salman Shahid, Sharanbasappa S. Karade, Pragati Agnihotri, Alexander Kolesnikov, S. Saif Hasan, Roy A. Mariuzza, "CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker," Structure 31 (10), 1149-1157 (2023). DOI: 10.1016/j.str.2023.07.013

Yaozong Chen, Jérémie Prévost, Irfan Ullah, Hugo Romero, Veronique Lisi, William D. Tolbert, Jonathan R. Grover, Shilei Ding, Shang Yu Gong, Guillaume Beaudoin-Bussières, Romain Gasser, Mehdi Benlarbi, Dani Vézina, Sai Priya Anand, Debashree Chatterjee, Guillaume Goyette, Michael W. Grunst, Ziwei Yang, Yuxia Bo, Fei Zhou, Kathie Béland, Xiaoyun Bai, Allison R. Zeher, Rick K. Huang, Dung N. Nguyen, Rebekah Sherburn, Di Wu, Grzegorz Piszczek, Bastien Paré, Doreen Matthies, Di Xia, Jonathan Richard, Priti Kumar, Walther Mothes, Marceline Côté, Pradeep D. Uchil, Vincent-Philippe Lavallée, Martin A. Smith, Marzena Pazgier, Elie Haddad, Andrés Finzi, "Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD," iScience 26 (1), 05783 (2023). DOI: 10.1016/j.isci.2022.105783

Victor S. Lelyveld, Ziyuan Fang, Jack W. Szostak, "Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity," Science 382, 423-429 (2023). DOI: 10.1126/science.adh5339

Nicholas L. Yan, Ian A. Wilson, Jeffery W. Kelly, "Crystal Structures of Diaryl Hydrazone and Sulfone Stabilizers in Complex with an Amyloidogenic Light Chain Reveal an Alternate Ligand-Binding Cavity," Isr. J. Chem. 63 (10-11), e202300002 (2023). DOI: 10.1002/ijch.202300002

Chinemerem P. Ogbu, Srajan Kapoor, Alex J. Vecchio, "Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin," Toxins 15 (11), 637 (2023). DOI: 10.3390/toxins15110637

Cecily Choy, Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lu, Daichao Wu, Ainslee Zou, Humza Hemani, Beverly A. Baptiste, Emily Wichmann, Qian Yang, Jeffrey Ciffelo, Rui Yin, Julia McKelvy, Denise Melvin, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Chee W. Chia, Jinshui Fan, Jeannie Ruffolo, Linda Zukley, Guixin Shi, Tomokazu Amano, Yang An, Osorio Meirelles, Wells W. Wu, Chao-Kai Chou, Rong-Fong Shen, Richard A. Willis, Minoru S.H. Ko, Yu-Tsueng Liu, Supriyo De, Brian G. Pierce, Luigi Ferrucci, Josephine Egan, Roy Mariuzza, Nan-Ping Weng, "SARS-CoV-2 infection establishes a stable and age-independent CD[superscript 8+] T cell response against a dominant nucleocapsid epitope using restricted T cell receptors," Nat. Commun. 14, 6725 (2023). DOI: 10.1038/s41467-023-42430-z

Johnny Mendoza, Meredith Purchal, Kazuhiro Yamada, Markos Koutmos, "Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo," Nat. Commun. 14, 6365 (2023). DOI: 10.1038/s41467-023-42037-4

Tyler M. McCullough, Anya Dhar, David L. Akey, Jamie R. Konwerski, David H. Sherman, Janet L. Smith, "Structure of a modular polyketide synthase reducing region," Structure 21 (9), 1109-1120 (2023). DOI: 10.1016/j.str.2023.05.019

Satchal K. Erramilli, Pawel K. Dominik, Dawid Deneka, Piotr Tokarz, Sangwoo S. Kim, Bharat G. Reddy, Blazej M. Skrobek, Olivier Dalmas, Eduardo Perozo, Anthony A. Kossiakoff, "Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA," J. Mol. Biol. 435 (17), 168192 (2023). DOI: 10.1016/j.jmb.2023.168192

Shelby D. Foor, Kalvis Brangulis, Anil K. Shakya, Vipin S. Rana, Sandhya Bista, Chrysoula Kitsou, Michael Ronzetti, Adit B. Alreja, Sara B. Linden, Amanda S. Altieri, Bolormaa Baljinnyam, Inara Akopjana, Daniel C. Nelson, Anton Simeonov, Osnat Herzberg, Melissa J. Caimano, Utpal Pal, "A unique borrelial protein facilitates microbial immune evasion," mBio 14 (5), e02135 (2023). DOI: 10.1128/mbio.02135-23

Alvina Sarosh, Stephen M. Kwong, Slade O. Jensen, Faith Northern, William G. Walton, Thomas C. Eakes, Matthew R. Redinbo, Neville Firth, Krystle J. McLaughlin, "pSK41/pGO1-family conjugative plasmids of Staphylococcus aureus encode a cryptic repressor of replication," Plasmid 128, 102708 (2023). DOI: 10.1016/j.plasmid.2023.102708

Prabhanshu Tripathi, Jarrod J. Mousa, Naga Sandhya Guntaka, Steven D. Bruner, "Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin," Acta Crystallogr. D 79 (9), 830-836 (2023). DOI: 10.1107/S2059798323005703

Anna T. Gres, Karen A. Kirby, William M. McFadden, Haijuan Du, Dandan Liu, Chaoyi Xu, Alexander J. Bryer, Juan R. Perilla, Jiong Shi, Christopher Aiken, Xiaofeng Fu, Peijun Zhang, Ashwanth C. Francis, Gregory B. Melikyan, Stefan G. Sarafianos, "Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization," Nat. Commun. 14, 5614 (2023). DOI: 10.1038/s41467-023-41197-7

Ketan D. Patel, Andrew M. Gulick, "Structural and functional insights into [delta]-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii," Commun. Biol. 6, 982 (2023). DOI: 10.1038/s42003-023-05362-4

Ruiqi Huang, Gabrielle Warner Jenkins, Yunjeong Kim, Robyn L. Stanfield, Amrinder Singh, Maria Martinez-Yamout, Gerard J. Kroon, Jonathan L. Torres, Abigail M. Jackson, Abigail Kelley, Namir Shaabani, Baisen Zeng, Michael Bacica, Wen Chen, Christopher Warner, Jasmina Radoicic, Joongho Joh, Krishani Dinali Perera, Huldah Sang, Tae Kim, Jianxiu Yao, Fangzhu Zhao, Devin Sok, Dennis R. Burton, Jeff Allen, William Harriman, Waithaka Mwangi, Donghoon Chung, John R. Teijaro, Andrew B. Ward, H. Jane Dyson, Peter E. Wright, Ian A. Wilson, Kyeong-Ok Chang, Duncan McGregor, Vaughn V. Smider, "The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2," Proc. Natl. Acad. Sci. USA 120 (39), e2303455120 (2023). DOI: 10.1073/pnas.2303455120

Nicholas D. Clark, Christopher Pham, Kurni Kurniyati, Ching Wooen Sze, Laurynn Coleman, Qin Fu, Sheng Zhang, Michael G. Malkowski, Chunhao Li, "Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors," PLoS Patho. 19 (9), e1011674 (2023). DOI: 10.1371/ journal.ppat.1011674

Lisa M. Eubanks, Tossapol Pholcharee, David Oyen, Yoshihiro Natori, Bin Zhou, Ian A. Wilson, Kim D. Janda, "An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression," ACS Chem. Neurosci. 14 (16), 2849-2856 (2023). DOI: 10.1021/acschemneuro.3c00455

Lena Hansen, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Jackson S Turner, Gabriel Ozorowski, Daniel Stadlbauer, Juha Vahokoski, Aaron J Schmitz, Amena A Rizk, Wafaa B Alsoussi, Shirin Strohmeier, Wenli Yu, José Alberto Choreño-Parra, Luis Jiménez-Alvarez, Alfredo Cruz-Lagunas, Joaquín Zúñiga, Philip A Mudd, Rebecca J Cox, Ian A Wilson, Andrew B Ward, Ali H Ellebedy, Florian Krammer, "Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo," Immunity 56 (8), 1927-1938 (2023). DOI: 10.1016/j.immuni.2023.07.004

Benjamin D. Dratch, Kirklin L. McWhorter, Tamra C. Blue, Stacey K. Jones, Samantha M. Horwitz, Katherine M. Davis, "Insights into Substrate Recognition by the Unusual Nitrating Enzyme RufO," ACS Chem. Biol. 18 (8), 1713-1718 (2023). DOI: 10.1021/acschembio.3c00328

Cuizheng Zhang, Victoria E. Paluzzi, Ruojie Sha, Natasha Jonoska, Chengde Mao, "Implementing Logic Gates by DNA Crystal Engineering," Adv. Mater. 35 (33), 2302345 (2023). DOI: 10.1002/adma.202302345

Paule Hermet, Benoıt Delache, Cecile Herate, Esther Wolf, Gaily Kivi, Erkki Juronen, Karl Mumm, Eva Zusinaite, Denis Kainov, Eve Sankovski, Kai Virumae, Anu Planken, Andres Merits, Jessica E. Besaw, Ai Woon Yee, Takefumi Morizumi, Kyumhyuk Kim, Anling Kuo, Asma Berriche, Nathalie Dereuddre-Bosquet, Quentin Sconosciuti, Thibaut Naninck, Francis Relouzat, Mariangela Cavarelli, Mart Ustav, Derek Wilson, Oliver P. Ernst, Andres Mannik, Roger LeGrand, Mart Ustav, Jr, "Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates," PLoS Patho. 19 (8), e1011532 (2023). DOI: 10.1371/journal. ppat.1011532

Chau Ngo, William Fried, Saba Aliyari, Joshua Feng, Chao Qin, Shilei Zhang, Hanjing Yang, Jean Shanaa, Pinghui Feng, Genhong Cheng, Xiaojiang S. Chen, Chao Zhang, "Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease," J. Med. Chem. 66 (17), 12237-12248 (2023). DOI: 10.1021/acs.jmedchem.3c00810

Kayla Glockzin, Kathleen M. Meneely, Ryan Hughes, Sean W. Maatouk, Grace E. Piña, Kajitha Suthagar, Keith Clinch, Joshua N. Buckler, Audrey L. Lamb, Peter C. Tyler, Thomas D. Meek, Ardala Katzfuss, "Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors," Biochemistry-US 62 (14), 2182-2201 (2023). DOI: 10.1021/acs.biochem.3c00116

Yiwei Liu, Nicholas M. Marshall, Sheng-Song Yu, Wantae Kim, Yi-Gui Gao, Howard Robinson, Mark J. Nilges, Yan Zhang, Siu Yee New, Yi Lu, "Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin," Inorg. Chem. 62 (29), 11618-11625 (2023). DOI: 10.1021/acs.inorgchem.3c01365

Hyun Kyung Lee, Yun-Tzai Lee, Lixin Fan, Haley M. Wilt, Chelsie E. Conrad, Ping Yu, Jinwei Zhang, Genbin Shi, Xinhua Ji, Yun-Xing Wang, Jason R. Stagno, "Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state," Structure 31 (7), 848-859 (2023). DOI: 10.1016/j.str.2023.05.003

Kaci Erwin, R. Yvette Moreno, Bert-Jan Baas, Y. Jessie Zhang, Christian P. Whitman, "Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases," Biochemistry-US 62 (16), 2461-2471 (2023). DOI: 10.1021/acs.biochem.3c00180

Raheel Ahmad, Alexei M. Tyryshkin, Lingjun Xie, William A. Hansen, Brahm J. Yachnin, Thomas J. Emge, Ashraf Mashrai, Sagar D. Khare, Spencer Knapp, "A Bis(imidazole)-based cysteine labeling tool for metalloprotein assembly," J. Inorg. Biochem. 244, 112206 (2023). DOI: 10.1016/j.jinorgbio.2023.112206

Romila Mascarenhas, Markus Ruetz, Harsha Gouda, Natalie Heitman, Madeline Yaw, Ruma Banerjee, "Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B[subscript 12] delivery and repair," Nat. Commun. 14, 4332 (2023). DOI: 10.1038/s41467-023-40077-4

Raimund Nagel, Liza E. Alexander, Charles E. Stewart Jr., Reuben J. Peters, "Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis," Proc. Natl. Acad. Sci. USA 120 (26), e2221549120 (2023). DOI: 10.1073/pnas.2221549120

Laetitia Misson Mindrebo, Hejun Liu, Gabriel Ozorowski, Quoc Tran, Jordan Woehl, Irene Khalek, Jessica M. Smith, Shawn Barman, Fangzhu Zhao, Celina Keating, Oliver Limbo, Megan Verma, Jingjia Liu, Robyn L. Stanfield, Xueyong Zhu, Hannah L. Turner, Devin Sok, Po-Ssu Huang, Dennis R. Burton, Andrew B. Ward, Ian A. Wilson, Joseph G. Jardine, "Fully synthetic platform to rapidly generate tetravalent bispecific nanobody–based immunoglobulins," Proc. Natl. Acad. Sci. USA 120 (24), e2216612120 (2023). DOI: 10.1073/pnas.2216612120

Erik B. Faber, Luxin Sun, Jian Tang, Emily Roberts, Sornakala Ganeshkumar, Nan Wang, Damien Rasmussen, Abir Majumdar, Laura E. Hirsch, Kristen John, An Yang, Hira Khalid, Jon E. Hawkinson, Nicholas M. Levinson, Vargheese Chennathukuzhi, Daniel A. Harki, Ernst Schönbrunn, Gunda I. Georg, "Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding," Nat. Commun. 14, 3213 (2023). DOI: 10.1038/s41467-023-38732-x

Partha Radhakrishnan Santhakumari, KanagaVijayan Dhanabalan, Saniya Virani, Amber S. Hopf-Jannasch, Joshua B. Benoit, Gaurav Chopra, Ramaswamy Subramanian, "Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins," PLoS One 18 (6), e0280009 (2023). DOI: 10.1371/journal.pone.0280009

Huong T. Kratochvil, Laura C. Watkins, Marco Mravic, Jessica L. Thomaston, John M. Nicoludis, Noah H. Somberg, Lijun Liu, Mei Hong, Gregory A. Voth, William F. DeGrado, "Transient water wires mediate selective proton transport in designed channel proteins," Nat. Chem. 15, 1012-1021 (2023). DOI: 10.1038/s41557-023-01210-4

Collin Joyce, Sasha Murrell, Ben Murrell, Oluwarotimi Omorodion, Lorena S. Ver, Nancy Carrico, Raiza Bastidas, Rebecca Nedellec, Michael Bick, Jordan Woehl, Fangzhu Zhao, Alison Burns, Shawn Barman, Michael Appel, Alejandra Ramos, Lalinda Wickramasinghe, Kemal Eren, Thomas Vollbrecht, Davey M. Smith, Sergei L.Kosakovsky Pond, Ryan McBride, Charli Worth, Facundo Batista, Devin Sok, Pascal Poignard, Bryan Briney, Ian A. Wilson, Elise Landais, Dennis R. Burton, "Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies," PLoS Patho. 19 (6), e1011416 (2023). DOI: 10.1371/journal.ppat.1011416

Viet Q. Le, Bo Zhao, Siddanth Ramesh, Cameron Toohey, Adam DeCosta, Julian Mintseris, Xinyue Liu, Steven Gygi, Timothy A. Springer, "A specialized integrin-binding motif enables proTGF-[beta]2 activation by integrin [alpha]V[beta]6 but not [alpha]V[beta]8," Proc. Natl. Acad. Sci. USA 120 (24), e2304874120 (2023). DOI: 10.1073/pnas.2304874120

Phillip M. Danby, Andrew Jeong, Lyann Sim, Ryan P. Sweeney, Jacob F. Wardman, Ryan Karimi, Andreas Geissner, Liam J. Worrall, Jolene.P. Reid, Natalie C.J. Strynadka, Stephen G. Withers, "Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors," Angew. Chem. Int. Ed. 62 (21), e202301258 (2023). DOI: 10.1002/anie.202301258

Adam D. Lietzan, Joshua B. Simpson, William G. Walton, Parth B. Jariwala, Yongmei Xu, Marcella H. Boynton, Jian Liu, Matthew R. Redinbo, "Microbial [beta]-glucuronidases drive human periodontal disease etiology," Sci. Advances 9 (18), eadg3390 (2023). DOI: 10.1126/sciadv.adg3390

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Yupeng Feng, Meng Yuan, John M. Powers, Mengyun Hu, Jennifer E. Munt, Prabhu S. Arunachalam, Sarah R. Leist, Lorenza Bellusci, JungHyun Kim, Kaitlin R. Sprouse, Lily E. Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa M. Shirreff, Michael L. Mallory, Trevor D. Scobey, Alberto Moreno, Derek T. O’Hagan, Harry Kleanthous, Francois J. Villinger, David Veesler, Neil P. King, Mehul S. Suthar, Surender Khurana, Ralph S. Baric, Ian A. Wilson, Bali Pulendran, "Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine," Sci. Transl. Med. 15 (695), eadg7404 (2023). DOI: 10.1126/scitranslmed.adg7404

Audrey Kassardjian, Eric Sun, Jamie Sookhoo, Krithika Muthuraman, Kayluz Frias Boligan, Iga Kucharska, Edurne Rujas, Arif Jetha, Donald R. Branch, Shawn Babiuk, Brian Barber, Jean-Philippe Julien, "Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses," Cell Reports 42 (4), 112391 (2023). DOI: 10.1016/j.celrep.2023.112391

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Nivea Pereira de Sa, Kalani Jayanetti, Dominick Rendina, Timothy Clement, Veronica Soares Brauer, Caroline Mota Fernandes, Iwao Ojima, Michael V Airola, Maurizio Del Poeta, "Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections," mBio 14 (2), e0033923 (2023). DOI: 10.1128/mbio.00339-23

Jian Liu, Carrie Hiser, Fei Li, Robert Hall, R. Michael Garavito, Shelagh Ferguson-Miller, "New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity," Biochemistry-US 62 (7), 1262-1273 (2023). DOI: 10.1021/acs.biochem.2c00612

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Cuizheng Zhang, Jiemin Zhao, Brandon Lu, Nadrian C. Seeman, Ruojie Sha, Nicholas Noinaj, Chengde Mao, "Engineering DNA Crystals toward Studying DNA–Guest Molecule Interactions," J. Am. Chem. Soc. 145 (8), 4853-4859 (2023). DOI: 10.1021/jacs.3c00081

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Vamseedhar Rayaprolu, Benjamin O. Fulton, Ashique Rafique, Emilia Arturo, Dewight Williams, Chitra Hariharan, Heather Callaway, Amar Parvate, Sharon L. Schendel, Diptiben Parekh, Sean Hui, Kelly Shaffer, Kristen E. Pascal, Elzbieta Wloga, Stephanie Giordano, Nicole Negron, Min Ni, Richard Copin, Gurinder S. Atwal, Matthew Franklin, Ruth Mabel Boytz, Callie Donahue, Robert Davey, Alina Baum, Christos A. Kyratsous, Erica Ollmann Saphire, "Structure of the Inmazeb cocktail and resistance to Ebola virus escape," Cell Host Microbe 31 (2), 260-272 (2023). DOI: 10.1016/j.chom.2023.01.002

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Wai Kwan Tang, Camila H Coelho, Kazutoyo Miura, Bergeline C Nguemwo Tentokam, Nichole D Salinas, David L Narum, Sara A Healy, Issaka Sagara, Carole A Long, Patrick E Duffy, Niraj H Tolia, "A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine," Immunity 56 (2), 433-443 (2023). DOI: 10.1016/j.immuni.2023.01.012

Anil Kumar Marapaka, Alessio Nocentini, Molly S. Youse, Weiwei An, Katrina J. Holly, Chittaranjan Das, Ravi Yadav, Mohamed N. Seleem, Claudiu T. Supuran, Daniel P. Flaherty, "Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae [alpha]-Carbonic Anhydrase," ACS Med. Chem. Lett. 14 (1), 103-109 (2023). DOI: 10.1021/acsmedchemlett.2c00471

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Brian J. Graham, Ian W. Windsor, Ronald T. Raines, "Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability," ACS Med. Chem. Lett. 14 (2), 171-175 (2023). DOI: 10.1021/acsmedchemlett.2c00464

Zhiwen Liu, Sebastian Rivera, Sean A. Newmister, Jacob N. Sanders, Qiuyue Nie, Shuai Liu, Fanglong Zhao, Joseph D. Ferrara, Hao-Wei Shih, Siddhant Patil, Weijun Xu, Mitchell D. Miller, George N. Phillips, K.N. Houk, David H. Sherman, Xue Gao, "An NmrA-like enzyme-catalysed redox-mediated Diels–Alder cycloaddition with anti-selectivity," Nat. Chem. 15, 526-534 (2023). DOI: 10.1038/s41557-022-01117-6

Cherrelle Dacon, Linghang Peng, Ting-Hui Lin, Courtney Tucker, Chang-Chun D. Lee, Yu Cong, Lingshu Wang, Lauren Purser, Andrew J.R. Cooper, Jazmean K. Williams, Chul-Woo Pyo, Meng Yuan, Ivan Kosik, Zhe Hu, Ming Zhao, Divya Mohan, Mary Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, Michael Murphy, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona S. Weinberg, Amarendra Pegu, Daniel E. Geraghty, Edgar Davidson, Benjamin J. Doranz, Iyadh Douagi, Susan Moir, Jonathan W. Yewdell, Connie Schmaljohn, Peter D. Crompton, John R. Mascola, Michael R. Holbrook, David Nemazee, Ian A. Wilson, Joshua Tan, "Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses," Cell Host Microbe 31 (1), 97-111 (2023). DOI: 10.1016/j.chom.2022.10.010

Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, Henry L. Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H. Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M. Levinson, Ernst Schönbrunn, Jon E. Hawkinson, Gunda I. Georg, "Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice," J. Med. Chem. 66 (3), 1928-1940 (2023). DOI: 10.1021/acs.jmedchem.2c01731

Hayley L. Knox, Erica K. Sinner, Craig A. Townsend, Amie K. Boal, Squire J. Booker, "Structure of a B[subscript 12]-dependent radical SAM enzyme in carbapenem biosynthesis," Nature 602, 343-348 (2022). DOI: 10.1038/s41586-021-04392-4

Dake Liu, Thisuri N. Wanniarachchi, Guangde Jiang, Gustavo Seabra, Shugeng Cao, Steven D. Bruner, Yousong Ding, "Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles," RSC Chem. Biol. 3 (4), 436-446 (2022). DOI: 10.1039/D1CB00238D

Samantha M. Horwitz, Tamra C. Blue, Joseph A. Ambarian, Shotaro Hoshino, Mohammad R. Seyedsayamdost, Katherine M. Davis, "Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines," RSC Chem. Biol. 3 (4), 420-425 (2022). DOI: 10.1039/D1CB00255D

John Blazeck, Christos S. Karamitros, Kyle Ford, Catrina Somody, Ahlam Qerqez, Kyle Murray, Nathaniel T. Burkholder, Nicholas Marshall, Anirudh Sivakumar, Wei-Cheng Lu, Bing Tan, Candice Lamb, Yuri Tanno, Menna Y. Siddiqui, Norah Ashoura, Silvia Coma, Xiaoyan M. Zhang, Karen McGovern, Yoichi Kumada, Yan Jessie Zhang, Mark Manfredi, Kenneth A. Johnson, Sheena D’Arcy, Everett Stone, George Georgiou, "Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme," Nat. Catalysis 5, 952-867 (2022). DOI: 10.1038/s41929-022-00856-6

Tim Springer, "Albert Lasker Basic Medical Research Award," (2022).

Hanjing Yang, Kyumin Kim, Shuxing Li, Josue Pacheco, Xiaojiang S. Chen, "Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G," Nat. Commun. 13, 7498 (2022). DOI: 10.1038/s41467-022-35201-9

Edward P. Harvey, Jung-Eun Shin, Meredith A. Skiba, Genevieve R. Nemeth, Joseph D. Hurley, Alon Wellner, Ada Y. Shaw, Victor G. Miranda, Joseph K. Min, Chang C. Liu, Debora S. Marks, Andrew C. Kruse, "An in silico method to assess antibody fragment polyreactivity," Nat. Commun. 13, 7554 (2022). DOI: 10.1038/s41467-022-35276-4

Travis J. Morgenstern, Neha Nirwan, Erick O. Hernández-Ochoa, Hugo Bibollet, Papiya Choudhury, Yianni D. Laloudakis, Manu Ben Johny, Roger A. Bannister, Martin F. Schneider, Daniel L. Minor Jr., Henry M. Colecraft, "Selective posttranslational inhibition of Ca[subscript V beta subscript 1]-associated voltage-dependent calcium channels with a functionalized nanobody," Nat. Commun. 13, 7556 (2022). DOI: 10.1038/s41467-022-35025-7

Pratik R. Chheda, Nicholas Nieto, Supreet Kaur, John M. Beck, Josh R. Beck, Richard Honzatko, Robert J. Kerns, Scott W. Nelson, "Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum," Eur. J. Med. Chem. 243, 114751 (2022). DOI: 10.1016/j.ejmech.2022.114751

Sherry Bermeo, Andrew Favor, Ya-Ting Chang, Andrew Norris, Scott E. Boyken, Yang Hsia, Hugh K. Haddox, Chunfu Xu, T.J. Brunette, Vicki H. Wysocki, Gira Bhabha, Damian C. Ekiert, David Baker, "De novo design of obligate ABC-type heterotrimeric proteins," Nat. Struct. Mol. Biol. 29, 1266-1276 (2022). DOI: 10.1038/s41594-022-00879-4

Gautam Srivastava, Rakhi Bajaj, Ganesan Senthil Kumar, Antoine Gaudreau-Lapierre, Hannah Nicolas, Delphine Chamousset, Dale Kreitler, Wolfgang Peti, Laura Trinkle-Mulcahy, Rebecca Page, "The ribosomal RNA processing 1B:protein phosphatase 1 holoenzyme reveals non-canonical PP1 interaction motifs," Cell Reports 41 (9), 111726 (2022). DOI: 10.1016/j.celrep.2022.111726

Shoucheng Du, John J. Alvarado, Thomas E. Wales, Jamie A. Moroco, John R. Engen, Thomas E. Smithgall, "ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr," Structure 30 (11), 1508-1517 (2022). DOI: 10.1016/j.str.2022.08.008

Benjamin C. Campbell, Maria G. Paez-Segala, Loren L. Looger, Gregory A. Petsko, Ce Feng Liu, "Chemically stable fluorescent proteins for advanced microscopy," Nat. Methods 19, 1612-1621 (2022). DOI: 10.1038/s41592-022-01660-7

Vinayak Singh, Anna E. Grzegorzewicz, Stephen Fienberg, Rudolf Müller, Lutete Peguy Khonde, Olalla Sanz, Salvatore Alfonso, Beatriz Urones, Gerard Drewes, Marcus Bantscheff, Sonja Ghidelli-Disse, Thomas R. Ioerger, Bhanupriya Angala, Jiuyu Liu, Richard E. Lee, James C. Sacchettini, Inna V. Krieger, Mary Jackson, Kelly Chibale, Sandeep R. Ghorpade, "1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis," ACS Infect. Dis. 8 (11), 2315-2326 (2022). DOI: 10.1021/acsinfecdis.2c00392

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Jinuk Kim, Wonhee Han, Taeyong Park, Eun Jin Kim, Injin Bang, Hyun Sik Lee, Yejing Jeong, Kyeonghwan Roh, Jeesoo Kim, Jong-Seo Kim, Chanhee Kang, Chaok Seok, Jin-Kwan Han, Hee-Jung Choi, "Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains," Nat. Commun. 11, 5357 (2020). DOI: 10.1038/s41467-020-19155-4

Marco Lolicato, Andrew M. Natale, Fayal Abderemane-Ali, David Crottès, Sara Capponi, Ramona Duman, Armin Wagner, John M. Rosenberg, Michael Grabe, Daniel L. Minor Jr., "K[subscript 2P] channel C-type gating involves asymmetric selectivity filter order-disorder transitions," Sci. Advances 6 (44), eabc9174 (2020). DOI: 10.1126/sciadv.abc9174

Jessica E. Besaw, Wei-Lin Ou, Takefumi Morizumi, Bryan T. Eger, Juan D. Sanchez Vasquez, Jessica H.Y. Chu, Andrew Harris, Leonid S. Brown, R.J. Dwayne Miller, Oliver P. Ernst, "The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants," J. Biol. Chem. 295 (44), 14793-14804 (2020). DOI: 10.1074/jbc.RA120.014118

Rafael Maldonado-Hernándezac, Orestes Quesada, José A. Lasalde-Dominiccia, "Biophysical characterization dataset of native nicotinic acetylcholine receptor in lipid-like detergent complexes," Data in Brief 32, 106230 (2020). DOI: 10.1016/j.dib.2020.106230

Qingpin Xiao, Lei Wang, Shreyas Supekar, Tao Shen, Heng Liu, Fei Ye, Junzhou Huang, Hao Fan, Zhiyi Wei, Cheng Zhang, "Structure of human steroid 5[alpha]-reductase 2 with the anti-androgen drug finasteride," Nat. Commun. 11, 5430 (2020). DOI: 10.1038/s41467-020-19249-z

Jeremy Guerin, Istvan Botos, Zijian Zhang, Karl Lundquist, James C Gumbart, Susan K Buchanan, "Structural insight into toxin secretion by contact-dependent growth inhibition transporters," eLIFE J. 9, e58100 (2020). DOI: 10.7554/eLife.58100

Chengcheng Fan, Douglas C. Rees, "Crystal structure of the Escherichia coli transcription termination factor Rho," Acta Crystallogr. F 76 (9), 398-405 (2020). DOI: 10.1107/S2053230X20010572

Samantha M. Ervin, Joshua B. Simpson, Morgan E. Gibbs, Benjamin C. Creekmore, Lauren Lim, William G. Walton, Raad Z. Gharaibeh, Matthew R. Redinbo, "Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases," Biochemistry-US 59 (40), 3939-3950 (2020). DOI: 10.1021/acs.biochem.0c00711

Anil R. Mhashal, Adrian Romero-Rivera, Lisa S. Mydy, Judith R. Cristobal, Andrew M. Gulick, John P. Richard, Shina C.L. Kamerlin, "Modeling the Role of a Flexible Loop and Active Site Side Chains in Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase," ACS Catal. 10 (19), 11253-11267 (2020). DOI: 10.1021/acscatal.0c02757

Sonu Kumar, Bin Ju, Benjamin Shapero, Xiaohe Lin, Li Ren, Lei Zhang, Dan Li, Zehua Zhou, Yi Feng, Cindy Sou, Colin J. Mann, Yanling Hao, Anita Sarkar, Jiali Hou, Christian Nunnally, Kunxue Hong, Shuo Wang, Xiangyang Ge, Bin Su, Elise Landais, Devin Sok, Michael B. Zwick, Linling He, Jiang Zhu, Ian A. Wilson, Yiming Shao, "A V[subscript H]1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersit," Sci. Advances 6 (38), eabb1328 (2020). DOI: 10.1126/sciadv.abb1328

Xiomaris M. Cotto-Rios, Bogos Agianian, Nadege Gitego, Emmanouil Zacharioudakis, Orsi Giricz, Yang Wu, Yiyu Zou, Amit Verma, Poulikos I. Poulikakos, Evripidis Gavathiotis, "Inhibitors of BRAF dimers using an allosteric site," Nat. Commun. 11, 4370 (2020). DOI: 10.1038/s41467-020-18123-2

Jun Liu, Rujin Cheng, Ned Van Eps, Nanxi Wang, Takefumi Morizumi, Wei-Lin Ou, Paul C. Klauser, Sharon Rozosky, Oliver P. Ernst, Lei Wang, "Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents," J. Am. Chem. Soc. 142 (40), 17057-17068 (2020). DOI: 10.1021/jacs.0c06820

Julia Greenfield, Xiaoran Shang, Heng Luo, Yan Zhou, Sara B. Linden, Ryan D. Heselpoth, Petr G. Leiman, Daniel C. Nelson, Osnat Herzberg, "Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7," Sci. Rep. 10, 15402 (2020). DOI: 10.1038/s41598-020-72373-0

Sandeep K. Ravala, Jesse B. Hopkins, Caoline B. Plescia, Samantha R. Allgood, Madison A. Kane, Jennifer N. Cash, Robert V. Stahelin, John J.G. Tesmer, "The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding," J. Biol. Chem. 295 (36), 12635-12647 (2020). DOI: 10.1074/jbc.RA120.014534

Kuglae Kim, Tao Che, Ouliana Panova, Jeffrey F. Di Berto, Jiankun Lyu, Brian E. Krumm, Daniel Wacker, Michael J. Robertson, Alpay B. Seven, David E. Nichols, Brian K. Shoichet, Georgios Skiniotis, Bryan L.Roth, "Structure of a Hallucinogen-Activated Gq-Coupled 5-HT[subscript 2A] Serotonin Receptor," Cell 182 (6), 1574-1588 (2020). DOI: 10.1016/j.cell.2020.08.024

Jose P. Llongueras, Samir Das, Jolien De Waele, Lucio Capulzini, Antonio Sorgente, Filip Van Petegem, Frank Bosmans, "Biophysical Investigation of Sodium Channel Interaction with [beta]-Subunit Variants Associated with Arrhythmias," Bioelectricity 2 (3), 269-278 (2020). DOI: 10.1089/bioe.2020.0030

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Xiao Lei, Jun Zhao, Jared M. Sagendorf, Niroop Rajashekar, Jiang Xu, Ana Carolina Dantas Machado, Chandani Sen, Remo Rohs, Pinghui Feng, Lin Chen, "Crystal Structures of Ternary Complexes of MEF2 and NKX2–5 Bound to DNA Reveal a Disease Related Protein–Protein Interaction Interface," J. Mol. Biol. 432 (19), 5499-5508 (2020). DOI: 10.1016/j.jmb.2020.07.004

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Yao Yao, Rameshwar U. Kadam, Chang-Chun David Lee, Jordan L. Woehl, Nicholas C. Wu, Xueyong Zhu, Seiya Kitamura, Ian A. Wilson, Dennis W. Wolan, "An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen," Proc. Natl. Acad. Sci. USA 117 (31), 18431-18438 (2020). DOI: 10.1073/pnas.2006893117

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Miriam L. Fichtner, Casey Vieni, Rachel L. Redler, Ljuvica Kolich, Ruoyi Jiang, Kazushiro Takata, Panos Stathopoulos, Pablo A. Suarez, Richard J. Nowak, Steven J. Burden, Damian C. Ekiert, Kevin C. O'Connor, "Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis," J. Exp. Med. 217 (12), e20200513 (2020). DOI: 10.1084/jem.20200513

Vikram V. Shende, Yogan Khatri, Sean A. Newmister, Jacob N. Sanders, Petra Lindovska, Fengan Yu, Tyler J. Doyon, Justin Kim, K.N. Houk, Mohammad Movassaghi, David H. Sherman, "Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase," J. Am. Chem. Soc. 142 (41), 17413-17424 (2020). DOI: 10.1021/jacs.0c06312

Britany Rufenach, Darren Christy, Bernhard E. Flucher, Jennifer M. Bui, Jörg Gsponer, Marta Campiglio, Filip Van Petegem, "Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling," Structure 28 (8), 922-932 (2020). DOI: 10.1016/j.str.2020.05.005

Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua Wofford, Inna Krieger, Ashutosh Tripathi, John W. Patrick, Debra M. Eckert, Arthur Laganowsky, James Sacchettini, Paul Lindahl, Vytas A. Bankaitis, "A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins," eLIFE J. 9, e57081 (2020). DOI: 10.7554/eLife.57081

Christopher A. Cottrell, Jelle van Schooten, Charles A. Bowman, Meng Yuan, David Oyen, Mia Shin, Robert MorpurgoI, Patricia van der Woude, Marie ¨lle van Breemen, Jonathan L. Torres, Raj Patel, Justin Gross, Leigh M. Sewal, Jeffrey Copps, Gabriel OzorowskiI, Bartek NogalI, Devin SokI, Eva G. Rakasz, Celia LabrancheI, Vladimir Vigdorovich, Scott Christley, Diane G. Carnathan, Noah Sather, David Montefiori, Guido SilvestriI, Dennis R. Burton, John P. Moore, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J.van Gils, "Mapping the immunogenic landscape of nearnative HIV-1 envelope trimers in non-human primate," Pathog. Dis. 16 (8), e1008753 (2020). DOI: 10.1371/ journal.ppat.1008753

Chun-Liang Chen, Lake N. Paul, James C. Mermoud, Calvin Nicklaus Steussy, Cynthia V. Stauffacher, "Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase," Nat. Commun. 11, 3969 (2020). DOI: 10.1038/s41467-020-17733-0

Sarah A.H. Hulgan, Abhishek A. Jalan, I-Che Li, Douglas R. Walker, Mitchell D. Miller, Abigael J. Kosgei, Weijun Xu, George N. Phillips Jr., Jeffrey D. Hartgerink, "Covalent Capture of Collagen Triple Helices Using Lysine–Aspartate and Lysine–Glutamate Pairs," Biomacromolecules 21 (9), 3772-3781 (2020). DOI: 10.1021/acs.biomac.0c00878

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Nemanja Vuksanovic, Xuechen Zhu, Dante A. Serrano, Vilja Siitonen, Mikko Metsä-Ketelä, Charles E. Melançon III, Nicholas R. Silvaggi, "Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis," Acta Crystallogr. F 76 (8), 372-383 (2020). DOI: 10.1107/S2053230X20009814

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Thomas C. Chamberlain, Sylvia T. Cheung, Jeff S.J. Yoon, Andrew Ming-Lum, Bernd R. Gardill, Soroush Shakibakho, Edis Dzananovic, Fuqiang Ban, Abrar Samiea, Kama ldeep Jawanda, John Priatel, Gerald Krystal, Christopher J. Ong, Artem Cherkasov, Raymond J. Andersen, Sean A. McKenna, Filip Van Petegem, Alice L-F. Mui, "Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes," iScience 23 (8), 101433 (2020). DOI: 10.1016/j.isci.2020.101433

Ngango Y. Rugema, Elisabeth E. Garland-Kuntz, Monita Sieng, Kaushik Muralidharan, Michelle M. Van Camp, Hannah O’Neill, William Mbongo, Arielle F. Selvia, Andrea T. Marti, Amanda Everly, Emmanda McKenzie, Angeline M. Lyon, "Structure of phospholipase C[epsilon] reveals an integrated RA1 domain and previously unidentified regulatory elements," Commun. Biol. 3, 445 (2020). DOI: 10.1038/s42003-020-01178-8

Carmen Schwechheimer, Kassidy Hebert, Sarvind Tripathi, Praveen K. Singh, Kyle A. Floyd, Elise R. Brown, Monique E. Porcella, Jacqueline Osorio, Joseph T.M. Kiblen, Fernando A. Pagliai, Knut Drescher, Seth M. Rubin, Fitnat H. Yildiz, "A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae," PLoS Patho. 16 (8), e1008745 (2020). DOI: 10.1371/journal.ppat.1008745

Inna V. Krieger, Vladimir Kuznetsov, Jeng-Yih Chang, Junjie Zhang, Samir H. Moussa, Ryland F. Young, James C. Sacchettini, "The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition," J. Mol. Biol. 432 (16), 4623-4636 (2020). DOI: 10.1016/j.jmb.2020.06.013

Christina A. Le, Daniel S. Harvey, Stephen G. Aller, "Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein," IUCrJ 7 (4), 663-672 (2020). DOI: 10.1107/S2052252520005709

Shoji Maeda, Jun Xu, Francois Marie N. Kadji, Mary J. Clark, Jiawei Zhao, Naotaka Tsutsumi, Junken Aoki, Roger K. Sunahara, Asuka Inoue, K. Christopher Garcia, Brian K. Kobilka, "Structure and selectivity engineering of the M[subscript 1] muscarinic receptor toxin complex," Science 369, 161-167 (2020). DOI: 10.1126/science.aax2517

Yuta Tanaka, Osamu Kurasawa, Akihiro Yokota, Michael G. Klein, Bunnai Saito, Shigemitsu Matsumoto, Masanori Okaniwa, Geza Ambrus-Aikelin, Noriko Uchiyama, Daisuke Morishita, Hiromichi Kimura, Shinichi Imamura, "New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase," ACS Med. Chem. Lett. 11 (8), 1645-1652 (2020). DOI: 10.1021/acsmedchemlett.0c00331

Rochelle R. Dotas, Trang T. Nguyen, Charles E. Stewart Jr, Rodolfo Ghirlando, Davit A. Potoyan, Vincenzo Venditti, "Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I," J. Mol. Biol. 432 (16), 4481-4498 (2020). DOI: 10.1016/j.jmb.2020.05.024

Zhonghua Liu, Chuanping Wang, Jie Yang, Yinghua Chen, Bowen Zhou, Derek W. Abbott, Tsan Sam Xiao, "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage," Immunity 53 (4), 106-114 (2020). DOI: 10.1016/j.immuni.2020.06.007

Ian J. Campbell, Olmos Jose Luis Jr., Weijun Xu, Dimithree Kahanda, Joshua T. Atkinson, Othneil Noble Sparks, Mitchell D. Miller, George N. Phillips Jr., George N. Bennett, Jonathan J. Silberg, "Prochlorococcus phage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases," J. Biol. Chem. 295 (31), 10610-10623 (2020). DOI: 10.1074/jbc.RA120.013501

Linah N. Rusere, Gordon J. Lockbaum, Mina Henes, Sook-Kyung Lee, Ean Spielvogel, Desaboini Nageswara Rao, Klajdi Kosovrasti, Ellen A. Nalivaika, Ronald Swanstrom, Nese Kurt Yilmaz, Celia A. Schiffer, Akbar Ali, "Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere," J. Med. Chem. 63 (15), 8296-8313 (2020). DOI: 10.1021/acs.jmedchem.0c00529

Jan Hellmann, Matthäus Drabek, Jie Yin, Jakub Gunera, Theresa Pröll, Frank Kraus, Christopher J. Langmead, Harald Hübner, Dorothee Weikert, Peter Kolb, Daniel M. Rosenbaum, Peter Gmeiner, "Structure-based development of a subtype-selective orexin 1 receptor antagonist," Proc. Natl. Acad. Sci. USA 117 (30), 18059-18067 (2020). DOI: 10.1073/pnas.2002704117

Tsung-Han Chou, Nami Tajima, Annabel Romero-Hernandez, Hiro Furukawa, "Structural basis of functional transitions in mammalian NMDA receptors," Cell 182 (2), 357-371 (2020). DOI: 10.1016/j.cell.2020.05.052

Netanel Tzarum, Erick Giang, Rameshwar U. Kadam, Fang Chen, Kenna Nagy, Elias H. Augestad, Rodrigo Velázquez-Moctezuma, Zhen-Yong Keck, Yuanzi Hua, Robyn L. Stanfield, Marlene Dreux, Jannick Prentoe, Steven K.H. Foung, Jens Bukh, Ian A. Wilson, Mansun Law, "An alternate conformation of HCV E2 neutralizing face as an additional vaccine target," Sci. Advances 6 (30), eabb5642 (2020). DOI: 10.1126/sciadv.abb5642

Dongxing Chen, Cheng Dong, Guangping Dong, Karthik Srinivasan, Jinrong Min, Nicholas Noinaj, Rong Huang, "Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues," J. Med. Chem. 63 (15), 8419-8431 (2020). DOI: 10.1021/acs.jmedchem.0c00770

Brianna D. Mackie, Dongxing Chen, Guangping Dong, Cheng Dong, Haley Parker, Christine E. Schaner Tooley, Nicholas Noinaj, Jinrong Min, Rong Huang, "Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies," J. Med. Chem. 63 (17), 9512-9522 (2020). DOI: 10.1021/acs.jmedchem.0c00689

Sohyoung Lee, Yi-An Yang, Shawn K. Milano, Tri Nguyen, Changhwan Ahn, Ji Hyun Sim, Andrew J. Thompson, Eric C. Hillpot, Gyeongshik Yoo, James C. Paulson, Jeongmin Song, "Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence," Cell Host Microbe 27 (6), 937-949 (2020). DOI: 10.1016/j.chom.2020.04.005

Eliza Ruben, William Planer, Mathivanan Chinnaraj, Zhiwei Chen, Xiaobing Zuo, Vittorio Pengo, Vincenzo De Filippis, Ravi K. Alluri, Keith R. McCrae, Paolo Macor, Francesco Tedesco, Nicola Pozzi, "The J-elongated conformation of [beta]2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome," J. Biol. Chem. 295 (31), 10794-10806 (2020). DOI: 10.1074/jbc.RA120.013939

Evan M. Alexander, Dale F. Kreitler, Valeria Guidolin, Alexander K. Hurben, Eric Drake, Peter W. Villalta, Silvia Balbo, Andrew M. Gulick, Courtney C. Aldrich, "Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca," ACS Infect. Dis. 6 (7), 1976-1997 (2020). DOI: 10.1021/acsinfecdis.0c00326

Wei-Cheng Lu, Achinto Saha, Wupeng Yan, Kendra Garrison, Candice Lamb, Renu Pandey, Seema Irani, Alessia Lodi, Xiyuan Lu, Stefano Tiziani, Yan Jessie Zhang, George Georgiou, John DiGiovanni, Everett Stone, "Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity," Proc. Natl. Acad. Sci. USA 117 (23), 13000-13011 (2020). DOI: 10.1073/pnas.1917362117

Daichao Wu, D. Travis Gallagher, Ragul Gowthaman, Brian G. Pierce, Roy A. Mariuzza, "Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen," Nat. Commun. 11, 2908 (2020). DOI: 10.1038/s41467-020-16755-y

Bryan J. Jones, Robert L. Evans III, Nathan J. Mylrea, Debayan Chaudhury, Christine Luo, Bo Guan, Colin T. Pierce, Wendy R. Gordon, Carrie M. Wilmot, Romas J. Kazlauskas, "Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity," PLoS One 15 (6), e0235341 (2020). DOI: 10.1371/journal.pone.0235341

Lee Makowski, "The Structural Basis of Amyloid Strains in Alzheimer’s Disease," ACS Biomater. Sci. Eng. 6 (5), 2498-2505 (2020). DOI: 10.1021/acsbiomaterials.9b01302

Robyn L. Stanfield, Zachary T. Berndsen, Ruiqi Huang, Devin Sok, Gabrielle Warner, Jonathan L. Torres, Dennis R. Burton, Andrew B. Ward, Ian A. Wilson, Vaughn V. Smider, "Structural basis of broad HIV neutralization by a vaccine-induced cow antibody," Sci. Advances 6 (22), eaba0468 (2020). DOI: 10.1126/sciadv.aba0468

Rajagopal Murugan, Stephen W. Scally, Giulia Costa, Ghulam Mustafa, Elaine Thai, Tizian Decker, Alexandre Bosch, Katherine Prieto, Elena A. Levashina, Jean-Philippe Julien, Hedda Wardemann, "Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs," Nat. Med. 26, 1135-1145 (2020). DOI: 10.1038/s41591-020-0881-9

Hala Ouzon-Shubeita, Hunmin Jung, Michelle H. Lee, Myong-Chul Koag, Seongmin Lee, "Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4," Biochem. J. 477 (9), 1601-1612 (2020). DOI: 10.1042/BCJ20200125

Shannon R. Esswein, Harry B. Gristick, Andrea Jurado, Avery Peace, Jennifer R. Keeffe, Yu E. Lee, Alisa V. Voll, Mohsan Saeed, Michel C. Nussenzweig, Charles M. Rice, Davide F. Robbiani, Margaret R. MacDonald, Pamela J. Bjorkman, "Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody," Proc. Natl. Acad. Sci. USA 117 (18), 9865-9875 (2020). DOI: 10.1073/pnas.1919269117

Ying Ye, Lei Du, Xingwang Zhang, Sean A. Newmister, Morgan McCauley, Juan V. Alegre-Requena, Wei Zhang, Shuai Mu, Atsushi Minami, Amy E. Fraley, Maria L. Adrover-Castellano, Nolan A. Carney, Vikram V. Shende, Feifei Qi, Hideaki Oikawa, Hikaru Kato, Sachiko Tsukamoto, Robert S. Paton, Robert M. Williams, David H. Sherman, Shengying Li, "Fungal-derived brevianamide assembly by a stereoselective semipinacolase," Nat. Catalysis 3, 497-506 (2020). DOI: 10.1038/s41929-020-0454-9

Weihong Zeng, Huan Ma, Weirong Fan, Yunru Yang, Caiying Zhang, John Arnaud KOMBE KOMBE, Xiaojiao Fan, Yuzhu Zhang, Zhongjun Dong, Zhen Shen, Ying Zhou, Meixiang Yang, Tengchuan Jin, "Structure determination of CAMP factor of Mobiluncus curtisii and insights into structural dynamics," Int. J. Biol. Macromol. 150, 1027-1036 (2020). DOI: 10.1016/j.ijbiomac.2019.10.107

Mateusz P. Czub, Katarzyna B. Handing, Barat S. Venkataramany, David R. Cooper, Ivan G. Shabalin, Wladek Minor, "Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma," J. Med. Chem. 63 (13), 6847-6862 (2020). DOI: 10.1021/acs.jmedchem.0c00225

Christian Holt, Louise Hamborg, Kelvin Lau, Malene Brohus, Anders Bundgaard Sørensen, Kamilla Taunsig Larsen, Cordula Sommer, Filip Van Petegem, Michael Toft Overgaard, Reinhard Wimmer, "The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor," J. Biol. Chem. 295 (22), 7620-7634 (2020). DOI: 10.1074/jbc.RA120.013430

Linling He, Netanel Tzarum, Xiaohe Lin, Benjamin Shapero, Cindy Sou, Colin J. Mann, Armando Stano, Lei Zhang, Kenna Nagy, Erick Giang, Mansun Law, Ian A. Wilson, Jiang Zhu, "Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines," Sci. Advances 6 (16), eaaz6225 (2020). DOI: 10.1126/sciadv.aaz6225

John M. Hausman, Sebastian Kenny, Shalini Iyer, Aditya Babar, Jiazhang Qiu, Jiaqi Fu, Zhao-Qing Luo, Chittaranjan Das, "The Two Deubiquitinating Enzymes from Chlamydia trachomatis Have Distinct Ubiquitin Recognition Properties," Biochemistry-US 59 (16), 1604-1617 (2020). DOI: 10.1021/acs.biochem.9b01107

Brenda P. Medellin, Emily B. Lancaster, Shoshana D. Brown, Swanand Rakhade, Patricia C. Babbitt, Christian P. Whitman, Yan Jessie Zhang, "Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer," Biochemistry-US 59 (16), 1592-1603 (2020). DOI: 10.1021/acs.biochem.0c00211

Robert S. Jansen, Lungelo Mandyoli, Ryan Hughes, Shoko Wakabayashi, Jessica T. Pinkham, Bruna Selbach, Kristine M. Guinn, Eric J. Rubin, James C. Sacchettini, Kyu Y. Rhee, "Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis," Nat. Commun. 11, 1960 (2020). DOI: 10.1038/s41467-020-15876-8

Ling Zhang, Ying-Hui Wang, Xing Zhang, Laura Lancaster, Jie Zhou, Harry F. Noller, "The structural basis for inhibition of ribosomal translocation by viomycin," Proc. Natl. Acad. Sci. USA 117 (19), 10271-10277 (2020). DOI: 10.1073/pnas.2002888117

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Jianchuan Wang, Yang Su, Roxana E. Iacob, John R. Engen, Timothy A. Springer, "General structural features that regulate integrin affinity revealed by atypical [alpha]V[beta]8," Nat. Commun. 10, 5481-1-5481 (2019). DOI: 10.1038/s41467-019-13248-5

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Jill F. Ellenbarger, Inna V. Krieger, Hsiao-ling Huang, Silvia Gómez-Coca, Thomas R. Ioerger, James C. Sacchettini, Steven E. Wheeler, Kim R. Dunbar, "Anion-[pi] Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids," J. Chem. Inf. Model. 58 (10), 2085-2091 (2018). DOI: 10.1021/acs.jcim.8b00417

Rakhi Bajaj, Mathieu Bollen, Wolfgang Peti, Rebecca Page, "KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive," Structure 26 (10), 1327-1336 (2018). DOI: 10.1016/j.str.2018.06.013

Gregory C. Campanello, Markus Ruetz, Greg J. Dodge, Harsha Gouda, Aditi Gupta, Umar T. Twahir, Michelle M. Killian, David Watkins, David S. Rosenblatt, Thomas C. Brunold, Kurt Warncke, Janet L. Smith, Ruma Banerjee, "Sacrificial Cobalt–Carbon Bond Homolysis in Coenzyme B[subscript 12] as a Cofactor Conservation Strategy," J. Am. Chem. Soc. 140 (41), 13205-13208 (2018). DOI: 10.1021/jacs.8b08659

Lei Wang, Dandan Yao, R.N.V. Krishna Deepak, Heng Liu, Qingpin Xiao, Hao Fan, Weimin Gong, Zhiy Wei, Cheng Zhang, "Structures of the Human PGD[subscript 2] Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition," Mol. Cell 72 (1), 48-59 (2018). DOI: 10.1016/j.molcel.2018.08.009

Abhishek Bandyopadhyay, Ned Van Eps, Bryan T. Eger, Sarah Rauscher, Ravikiran S. Yedidi, Tina Moroni, Graham M. West, Kelly Ann Robinson, Patrick R. Griffin, Jane Mitchell, Oliver P. Ernst, "A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin," J. Mol. Biol. 430 (21), 4102-4118 (2018). DOI: 10.1016/j.jmb.2018.08.009

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S. Kundhavai Natchiar, Sangita Venkataraman, Tina-Marie Mullen, Glen R. Nemerow, Vijay S. Reddy, "Revised Crystal Structure of Human Adenovirus Reveals the Limits on Protein IX Quasi-Equivalence and on Analyzing Large Macromolecular Complexes," J. Mol. Biol. 430 (21), 4132-4141 (2018). DOI: 10.1016/j.jmb.2018.08.011

Lisha Ha, Jennifer Colquhoun, Nicholas Noinaj, Chittaranjan Das, Paul M. Dunman, Daniel P. Flaherty, "Crystal structure of the ribonuclease-P-protein subunit from Staphylococcus aureus," Acta Crystallogr. F 74 (10), 632-637 (2018). DOI: 10.1107/S2053230X18011512

Thomas M. Moon, Éverton D. D'Andréa, Christopher W. Lee, Alexei Soares, Jean Jakoncic, Charlene Desbonnet, Monica Garcia-Solache, Lou B. Rice, Rebecca Page, Wolfgang Peti, "The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into [beta]-lactam resistance," J. Biol. Chem. 293 (48), 18574-18584 (2018). DOI: 10.1074/jbc.RA118.006052

Shao-Qing Zhang, Hai Huang, Junjiao Yang, Huong T. Kratochvil, Marco Lolicato, Yanxin Liu, Xiaokun Shu, Lijun Liu, William F. DeGrado, "Designed peptides that assemble into cross-[alpha] amyloid-like structures," Nat. Chem. Biol. 14, 870-875 (2018). DOI: 10.1038/s41589-018-0105-5

Mariia Novikova, Lucas J. Adams, Juan Fontana, Anna T. Gres, Muthukumar Balasubramaniam, Dennis C. Winkler, Sagar B. Kudchodkar, Ferri Soheilian, Stefan G. Sarafianos, Alasdair C. Steven, Eric O. Freeda, "Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation," mBio 9 (5), e01567-1-e01567-18 (2018). DOI: 10.1128/mBio.01567-18

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Greg Hicks, Zongchao Jia, "Structural Basis for the Lipopolysaccharide Export Activity of the Bacterial Lipopolysaccharide Transport System," Int. J. Mol. Sci. 19 (9), 2680-1-2680-12 (2018). DOI: 10.3390/ijms19092680

Greg J. Dodge, Danialle Ronnow, Richard E. Taylor, Janet L. Smith, "Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase," ACS Chem. Biol. 13 (9), 2699-2707 (2018). DOI: 10.1021/acschembio.8b00645

John D. McCorvy, Daniel Wacker, Sheng Wang, Bemnat Agegnehu, Jing Liu, Katherine Lansu, Alexandra R. Tribo, Reid H.J. Olsen, Tao Che, Jian Jin, Bryan L. Roth, "Structural determinants of 5-HT[subscript 2B] receptor activation and biased agonism," Nat. Struct. Mol. Biol. 25, 787-796 (2018). DOI: 10.1038/s41594-018-0116-7

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Brandyn R. West, Crystal L. Moyer, Liam B. King, Marnie L. Fusco, Jacob C. Milligan, Sean Hui, Erica Ollmann Saphire, "Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope," mBio 9 (5), e01674-1-e01674-18 (2018). DOI: 10.1128/mBio.01674-18

Bing-Rui Zhou, Jiansheng Jiang, Rodolfo Ghirlando, Davood Norouzi, K.N. Sathish Yadav, Hanqiao Feng, Rui Wang, Ping Zhang, Victor Zhurkin, Yawen Bai, "Revisit of Reconstituted 30-nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures," J. Mol. Biol. 430 (18B), 3093-3110 (2018). DOI: 10.1016/j.jmb.2018.06.020

Gopal P. Dahal, Ronald E. Viola, "Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase," Biochem. Biophys. Res. Commun. 503 (4), 2848-2854 (2018). DOI: 10.1016/j.bbrc.2018.08.053

Ti-Yen Lan, Jennifer L. Wierman, Mark W. Tate, Hugh T. Philipp, Jose M. Martin-Garcia, Lan Zhu, David Kissick, Petra Fromme, Robert F. Fischetti, Wei Liu, Veit Elser, Sol M. Gruner, "Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source," IUCrJ 5 (5), 548-558 (2018). DOI: 10.1107/S205225251800903X

Yun Ho Kim, David S. Gogerty, Bryce V. Plapp, "Substitutions of a buried glutamate residue hinder the conformational change in horse liver alcohol dehydrogenase and yield a surprising complex with endogenous 3′-Dephosphocoenzyme A," Arch. Biochem. Biophys. 653, 97-106 (2018). DOI: 10.1016/j.abb.2018.07.003

Benoît Desguin, Matthias Fellner, Olivier Riant, Jian Hu, Robert P. Hausinger, Pascal Hols, Patrice Soumillion, "Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase," J. Biol. Chem. 293 (32), 12303-12317 (2018). DOI: 10.1074/jbc.RA118.003741

Ashootosh Tripathi, Sung Ryeol Park, Andrew P. Sikkema, Hyo Je Cho, Jianfeng Wu, Brian Lee, Chuanwu Xi, Janet L. Smith, David H. Sherman, "A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit–Activating Enzyme CahJ," ChemBioChem 19 (15), 1595-1600 (2018). DOI: 10.1002/cbic.201800233

Daniel J. Falconer, Ganesh P. Subedi, Aaron M. Marcella, Adam W. Barb, "Antibody Fucosylation Lowers the Fc[gamma]RIIIa/CD16a Affinity by Limiting the Conformations Sampled by the N162-Glycan," ACS Chem. Biol. 13 (8), 2179-2189 (2018). DOI: 10.1021/acschembio.8b00342

Brandon R. Goblirsch, Buenafe T. Arachea, Daniel J. Councell, Michael C. Wiener, "Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24," Acta Crystallogr. D 74 (8), 739-747 (2018). DOI: 10.1107/S2059798318003431

Ignacio Mir-Sanchis, Ying Zhang Pigli, Phoebe Ann Rice, "Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements," Structure 26 (8), 1144-1150 (2018). DOI: 10.1016/j.str.2018.05.016

Matteo Bianchi, Hannah L. Turner, Bartek Nogal, Christopher A. Cottrell, David Oyen, Matthias Pauthner, Raiza Bastidas, Rebecca Nedellec, Laura E. McCoy, Ian A. Wilson, Dennis R. Burton, Andrew B. Ward, Lars Hangartner, "Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization," Immunity 49 (2), 288-300 (2018). DOI: 10.1016/j.immuni.2018.07.009

Thandeka Moyo, June Ereño-Orbea, Rajesh Abraham Jacob, Clara E. Pavillet, Samuel Mundia Kariuki, Emily N. Tangie, Jean-Philippe Julien, Jeffrey R. Dorfman, "Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11," J. Virol. 92 (14), e02261-1 -e02261-17 (2018). DOI: 10.1128/JVI.02261-17

Yajuan Li, Yi Huang, Xiaocong Cao, Xueying Yin, Xiangyu Jin, Sheng Liu, Jiansheng Jiang, Wei Jiang, Tsan Sam Xiao, Rongbin Zhou, Gang Cai, Bing Hu, Tengchuan Jin, "Functional and structural characterization of zebrafish ASC," FEBS J. 285 (14), 2691-2707 (2018). DOI: 10.1111/febs.14514

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Pengxiang Huang, Sanduo Zheng, Bradley M. Wierbowski, Youngchang Kim, Daniel Nedelcu, Laura Aravena, Jing Liu, Andrew C. Kruse, Adrian Salic, "Structural Basis of Smoothened Activation in Hedgehog Signaling," Cell 174 (2), 312-324 (2018). DOI: 10.1016/j.cell.2018.04.029

Chao Fan, Minrui Fan, Benjamin J. Orlando, Nathan M. Fastman, Jinru Zhang, Yan Xu, Melissa G. Chambers, Xiaofang Xu, Kay Perry, Maofu Liao, Liang Feng, "X-ray and cryo-EM structures of the mitochondrial calcium uniporter," Nature 559, 575-579 (2018). DOI: 10.1038/s41586-018-0330-9

Tengchuan Jin, Eric Brefo-Mensah, Weirong Fan, Weihong Zeng, Yajuan Li, Yuzhu Zhang, Michael Palmer, "Crystal structure of the Streptococcus agalactiae CAMP factor provides insights into its membrane-permeabilizing activity," J. Biol. Chem. 293 (30), 11867-11877 (2018). DOI: 10.1074/jbc.RA118.002336

Colin Havenar-Daughton, Anita Sarkar, Daniel W. Kulp, Laura Toy, Xiaozhen Hu, Isaiah Deresa, Oleksandr Kalyuzhniy, Kirti Kaushik, Amit A. Upadhyay, Sergey Menis, Elise Landais, Liwei Cao, Jolene K. Diedrich, Sonu Kumar, Torben Schiffner, Samantha M. Reiss, Grégory Seumois, John R. Yates, James C. Paulson, Steven E. Bosinger, Ian A. Wilson, William R. Schief, Shane Crotty, "The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen," Sci. Transl. Med. 10 (448), eaat0381-1-eaat0381 (2018). DOI: 10.1126/scitranslmed.aat0381

Celine Bergonzi, Michael Schwab, Tanushree Naik, David Daudé, Eric Chabrière, Mikael Elias, "Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties," Sci. Rep. 8, 11262-1-11262-13 (2018). DOI: 10.1038/s41598-018-28988-5

Samuel J. Pellock, Benjamin C. Creekmore, William G. Walton, Naimee Mehta, Kristen A. Biernat, Andrew P. Cesmat, Yamuna Ariyarathna, Zachary D. Dunn, Bo Li, Jian Jin, Lindsey I. James, Matthew R. Redinb, "Gut Microbial [beta]-Glucuronidase Inhibition via Catalytic Cycle Interception," ACS Central Sci. 4 (7), 868-879 (2018). DOI: 10.1021/acscentsci.8b00239

Fernando Aleman, Netanel Tzarum, Leopold Kong, Kenna Nagy, Jiang Zhu, Ian A. Wilson, Mansun Law, "Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors," Proc. Natl. Acad. Sci. USA 115 (29), 7569-7574 (2018). DOI: 10.1073/pnas.1802378115

Joel A. Rankin, Robert C. Mauban, Matthias Fellner, Benoît Desguin, John McCracken, Jian Hu, Sergey A. Varganov, Robert P. Hausinger, "Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism," Biochemistry-US 57 (23), 3244-3251 (2018). DOI: 10.1021/acs.biochem.8b00100

Kimmo Rantalainen, Zachary T. Berndsen, Sasha Murrell, Liwei Cao, Oluwarotimi Omorodion, Jonathan L. Torres, Mengyu Wu, Jeffrey Umotoy, Jeffrey Copps, Pascal Poignard, Elise Landais, James C. Paulson, Ian A. Wilson, Andrew B. Ward, "Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design," Cell Reports 23 (11), 3249-3261 (2018). DOI: 10.1016/j.celrep.2018.05.046

Alan T. Culbertson, Jacqueline J. Ehrlich, Jun-Yong Choe, Richard B. Honzatko, Olga A. Zabotina, "Structure of xyloglucan xylosyltransferase 1 reveals simple steric rules that define biological patterns of xyloglucan polymers," Proc. Natl. Acad. Sci. USA 115 (23), 6064-6069 (2018). DOI: 10.1073/pnas.1801105115

Lilian González-Segura, Carlos Mújica-Jiménez, Javier Andrés Juárez-Díaz, Rodrigo Güémez-Toro, León P. Martinez-Castilla, Rosario A. Muñoz-Clares, "Identification of the allosteric site for neutral amino acids in the maize C4 isozyme of phosphoenolpyruvate carboxylase: The critical role of Ser-100," J. Biol. Chem. 293 (26), 9945-9957 (2018). DOI: 10.1074/jbc.RA118.002884

Marianne Goris, Robert S. Magin, Håvard Foyn, Line M. Myklebust, Sylvia Varland, Rasmus Ree, Adrian Drazic, Parminder Bhambra, Svein I. Støve, Markus Baumann, Bengt Erik Haug, Ronen Marmorstein, Thomas Arnesen, "Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80," Proc. Natl. Acad. Sci. USA 115 (17), 4405-4410 (2018). DOI: 10.1073/pnas.1719251115

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Sanduo Zheng, Lok-To Sham, Frederick A. Rubino, Kelly P. Brock, William P. Robins, John J. Mekalanos, Debora S. Marks, Thomas G. Bernhardt, Andrew C. Kruse, "Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli," Proc. Natl. Acad. Sci. USA 115 (26), 6709-6714 (2018). DOI: 10.1073/pnas.1802192115

Katharina Imkeller, Stephen W. Scally, Alexandre Bosch, Gemma Pidelaserra Martí, Giulia Costa, Gianna Triller, Rajagopal Murugan, Valerio Renna, Hassan Jumaa, Peter G. Kremsner, B. Kim Lee Sim, Stephen L. Hoffman, Benjamin Mordmüller, Elena Levashina, Jean-Philippe Julien, Hedda Wardemann, "Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope," Science 360, 1358-1362 (2018). DOI: 10.1126/science.aar5304

Egor Svidritskiy, Andrei A. Korostelev, "Conformational Control of Translation Termination on the 70S Ribosome," Structure 26 (6), 821-828 (2018). DOI: 10.1016/j.str.2018.04.001

Heng Liu, Hee Ryung Kim, R.N. Deepak, Lei Wang, Ka Young Chung, Hao Fan, Zhiyi Wei, Cheng Zhang, "Orthosteric and allosteric action of the C5a receptor antagonists," Nat. Struct. Mol. Biol. 25, 472-481 (2018). DOI: 10.1038/s41594-018-0067-z

Scott T. Aoki, Douglas F. Porter, Aman Prasad, Marvin Wickens, Craig A. Bingman, Judith Kimble, "An RNA-Binding Multimer Specifies Nematode Sperm Fate," Cell Reports 23 (13), 3769-3775 (2018). DOI: 10.1016/j.celrep.2018.05.095

Timothy F. Miles, Katja Spiess, Kevin M. Jude, Naotaka Tsutsumi, John S. Burg, Jessica R. Ingram, Deepa Waghray, Gertrud M. Hjorto, Olav Larsen, Hidde L. Ploegh, Mette M. Rosenkilde, K. Christopher Garcia, "Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy," eLIFE J. 7, e35850-1-e35850-23 (2018). DOI: 10.7554/eLife.35850

Raoul De Gasparo, Elke Brodbeck‐Persch, Steve Bryson, Nina B. Hentzen, Marcel Kaiser, Emil F. Pai, R. Luise Krauth‐Siegel, François Diederich, "Biological Evaluation and X-Ray Co-Crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma," ChemMedChem 13 (9), 957-967 (2018). DOI: 10.1002/cmdc.201800067

Zhonghua Liu, Chuanping Wang, Joseph K. Rathkey, Jie Yang, George R. Dubyak, Derek W. Abbott, Tsan Sam Xiao, "Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition," Structure 26 (5), 778-784 (2018). DOI: 10.1016/j.str.2018.03.002

Daniel C. Bailey, Evan Alexander, Matthew R. Rice, Eric J. Drake, Lisa S. Mydy, Courtney C. Aldrich, Andrew M. Gulick, "Structural and functional delineation of aerobactin biosynthesis in hypervirulent Klebsiella pneumoniae," J. Biol. Chem. 293 (20), 7841-7852 (2018). DOI: 10.1074/jbc.RA118.002798

Ke Liu, Chao Xu, Ming Lei, Ally Yang, Peter Loppnau, Timothy R. Hughes, Jinrong Min, "Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA," J. Biol. Chem. 293 (19), 7344-7354 (2018). DOI: 10.1074/jbc.RA118.001785

Seema Irani, Nathchar Naowarojna, Yang Tang, Karan R. Kathuria, Shu Wang, Anxhela Dhembi, Norman Lee, Wupeng Yan, Huijue Lyu, Catherine E. Costello, Pinghua Liu, Yan Jessie Zhang, "Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism," Cell Chem. Biol. 25 (5), 519-529 (2018). DOI: 10.1016/j.chembiol.2018.02.002

Michael S. Little, Matthew R. Redinbo, "Crystal structure of the mouse innate immunity factor bacterial permeability-increasing family member A1," Acta Crystallogr. F 74 (5), 268-276 (2018). DOI: 10.1107/S2053230X18004600

Raoul De Gasparo, Elke Brodbeck‐Persch, Steve Bryson, Nina B. Hentzen, Marcel Kaiser, Emil F. Pai, "Biological Evaluation and X‐ray Co‐crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma," ChemMedChem 13 (9), 957-967 (2018). DOI: 10.1002/cmdc.201800067

Daniel C. Bailey, Evan Alexander, Matthew R. Rice, Eric J. Drake, Lisa S Mydy, Courtney C. Aldrich, Andrew M. Gulick, "Structural and Functional Delineation of Aerobactin Biosynthesis in Hypervirulentklebsiella Pneumoniae," J. Biol. Chem. 293 (20), 7841-7852 (2018). DOI: 10.1074/jbc.RA118.002798

Sneha Ray, Dale F. Kreitler, Andrew M. Gulick, Andrew S. Murkin, "The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition," ACS Chem. Biol. 13 (6), 1470-1473 (2018). DOI: 10.1021/acschembio.8b00225

Gongrui Guo, Martin R. Fuchs, Wuxian Shi, John Skinner, Evanna Berman, Craig M. Ogata, Wayne A. Hendrickson, Sean McSweeney, Qun Liu, "Sample manipulation and data assembly for robust microcrystal synchrotron crystallography," IUCrJ 5 (3), 238-246 (2018). DOI: 10.1107/S2052252518005389

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Daniel A. Bonsor, Qing Zhao, Barbara Schmidinger, Evelyn Weiss, Jingheng Wang, Daniel Deredge, Robert Beadenkopf, Blaine Dow, Wolfgang Fischer, Dorothy Beckett, Patrick L. Wintrode, Rainer Haas, Eric J. Sundberg, "The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA," EMBO J. 37 (13), e98664-1-e98664-17 (2018). DOI: 10.15252/embj.201798664

Mackenzie J. Parkera, Ailiena O. Maggiolob, William C. Thomasc, Albert Kima, Steve P. Meisburgerc, Nozomi Andoc, Amie K. Boalb, JoAnne Stubbe, "An endogenous dAMP ligand in Bacillus subtilis class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP," Proc. Natl. Acad. Sci. USA 115 (20), 4594-4603 (2018). DOI: 10.1073/pnas.1800356115

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Qifan Zhou, Chen Peng, Fangyu Du, Linbo Zhou, Yajie Shi, Yang Du, Dong dong Liu, Wenjiao Sun, Meixia Zhang, Guoliang Chen, "Design, synthesis and activity of BBI608 derivatives targeting on stem cells," Eur. J. Med. Chem. 151, 39-50 (2018). DOI: 10.1016/j.ejmech.2018.03.054

Robin J. Gunn, Brantley R. Herrin, Sharmistha Acharya, Max D. Cooper, Ian A. Wilson, "VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies," J. Mol. Biol. 430 (9), 1350-1367 (2018). DOI: 10.1016/j.jmb.2018.03.016

Nanette L.S. Que, Vincent M. Crowley, Adam S. Duerfeldt, Jinbo Zhao, Caitlin N. Kent, Brian S.J. Blagg, Daniel T. Gewirth, "Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Bindin," J. Med. Chem. 61 (7), 2793-2805 (2018). DOI: 10.1021/acs.jmedchem.7b01608

Rameshwar U. Kadam, Ian A. Wilson, "A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin," Proc. Natl. Acad. Sci. USA 115 (16), 4240-4245 (2018). DOI: 10.1073/pnas.1801999115

C.A. Starbird, Thomas M. Tomasiak, Prashant K. Singh, Victoria Yankovskaya, Elena Maklashina, Michael Eisenbach, Gary Cecchini, T.M. Iverson, "New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement," J. Struct. Biol. 202 (1), 100-104 (2018). DOI: 10.1016/j.jsb.2017.11.004

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Xiao Lei, Yi Kou, Yang Fu, Niroop Rajashekar, Haoran Shi, Fang Wu, Jiang Xu, Yibing Luo, Lin Chen, "The Cancer Mutation D83V Induces an [alpha]-Helix to [beta]-Strand Conformation Switch in MEF2B," J. Mol. Biol. 430 (8), 1157-1172 (2018). DOI: 10.1016/j.jmb.2018.02.012

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Harrison G. Jones, Tina Ritschel, Gabriel Pascual, Just P.J. Brakenhoff, Elissa Keogh, Polina Furmanova-Hollenstein, Ellen Lanckacker, Jehangir S. Wadia, Morgan S.A. Gilman, R. Anthony Williamson, Dirk Roymans, Angelique B. van t Wout, Johannes P. Langedijk, Jason S. McLellan, "Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies," PLoS Patho. 14 (3), e1006935-1-e1006935-23 (2018). DOI: 10.1371/journal.ppat.1006935

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Qilu Ye, Robert L. Campbell, Peter L. Davies, "Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation," J. Biol. Chem. 293 (11), 4056-4070 (2018). DOI: 10.1074/jbc.RA117.001097

Nicholas C. Wu, Andrew J. Thompson, Jia Xie, Chih-Wei Lin, Corwin M. Nycholat, Xueyong Zhu, Richard A. Lerner, James C. Paulson, Ian A. Wilson, "A Complex Epistatic Network Limits the Mutational Reversibility in the Influenza Hemagglutinin Receptor-Binding Site," Nat. Commun. 9 (1), 1264-1264 (2018). DOI: 10.1038/s41467-018-03663-5

Conor McMahon, Alexander S. Baier, Roberta Pascolutti, Marcin Wegrecki, Sanduo Zheng, Janice X. Ong, Sarah C. Erlandson, Daniel Hilger, Søren G.F. Rasmussen, Aaron M. Ring, Aashish Manglik, Andrew C. Kruse, "Yeast surface display platform for rapid discovery of conformationally selective nanobodies," Nat. Struct. Mol. Biol. 25, 289-296 (2018). DOI: 10.1038/s41594-018-0028-6

Egor Svidritskiy, Andrei A. Korostelev, "Mechanism of inhibition of translation termination by blasticidin S," J. Mol. Biol. 430 (5), 591-593 (2018). DOI: 10.1016/j.jmb.2018.01.007

Matthew R. Jensen, Brandon R. Goblirsch, Morgan A. Esler, James K. Christenson, Fatuma A. Mohamed, Lawrence P. Wackett, Carrie M. Wilmot, "The role of OleA His285 in orchestration of long‐chain acyl‐coenzyme A substrates," FEBS Lett. 592 (6), 987-998 (2018). DOI: 10.1002/1873-3468.13004

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Tyler M.M. Stack, Wenzong Li, William H. Johnson, Jr., Yan Jessie Zhang, Christian P. Whitman, "Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates," Biochemistry-US 57 (6), 1012-1021 (2018). DOI: 10.1021/acs.biochem.7b00899

Benjamin C. Campbell, Gregory A. Petsko, Ce Feng Liu, "Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors," Structure 26 (2), 225-237 (2018). DOI: 10.1016/j.str.2017.12.006

Aram Chang, Fayal Abderemane-Ali, Greg L. Hura, Nathan D. Rossen, Rachel E. Gate, Daniel L. Minor Jr., "A Calmodulin C-Lobe Ca[superscript 2+]-Dependent Switch Governs Kv7 Channel Function," Neuron 97 (4), 836-852 (2018). DOI: 10.1016/j.neuron.2018.01.035

Bo Zhao, Shutong Xu, Xianchi Dong, Chafen Lu, Timothy A. Springer, "Prodomain-growth factor swapping in the structure of pro-TGF-[beta]1," J. Biol. Chem. 293 (5), 1579-1589 (2018). DOI: 10.1074/jbc.M117.809657

Lauren K. Ely, Marco Lolicato, Tovo David, Kate Lowe, Yun Cheol Kim, Dharmaraj Samuel, Paul Bessette, Jorge L. Garcia, Thomas Mikita, Daniel L. Minor Jr., Shaun R. Coughlin, "Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent," Structure 26 (2), 187-198 (2018). DOI: 10.1016/j.str.2017.12.010

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Kate L. White, Matthew T. Eddy, Zhan-Guo Gao, Gye Won Han, Tiffany Lian, Alexander Deary, Nilkanth Patel, Kenneth A. Jacobson, Vsevolod Katritch, Raymond C. Stevens, "Structural Connection between Activation Microswitch and Allosteric Sodium Site in Gpcr Signaling," Structure 26 (2), 259-269 (2018). DOI: 10.1016/j.str.2017.12.013

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Daniel J. Falconer, Adam W. Barb, "Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1," PLoS One 13 (2), e0192123-1-e0192123-17 (2018). DOI: 10.1371/journal.pone.0192123

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Kazuhiro Yamadaa, Markos Koutmos, "The folate-binding module of Thermus thermophilus cobalamin-dependent methionine synthase displays a distinct variation of the classical TIM barrel: a TIM barrel with a ‘twist’," Acta Crystallogr. D 74 (1), 41-51 (2018). DOI: 10.1107/S2059798317018290

Liam B. King, Marnie L. Fusco, Andrew I. Flyak, Philipp A. Ilinykh, Kai Huang, Bronwyn Gunn, Robert N. Kirchdoerfer, Kathryn M. Hastie, Amandeep K. Sangha, Jens Meiler, Galit Alter, Alexander Bukreyev, James E. Crowe Jr., Erica Ollmann Saphire, "The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding," Cell Host Microbe 23 (1), 101-109 (2018). DOI: 10.1016/j.chom.2017.12.003

Eric M. Lewandowski, Kathryn G. Lethbridge, Ruslan Sanishvili, Joanna Skiba, Konrad Kowalski, Yu Chen, "Mechanisms of proton relay and product release by Class A [beta]‐lactamase at ultrahigh resolution," FEBS J. 285 (1), 87-100 (2018). DOI: 10.1111/febs.14315

Lingfei Liang, Haiyan Zhao, Bowen An, Liang Tang, "High-resolution structure of podovirus tail adaptor suggests repositioning of an octad motif that mediates the sequential tail assembly," Proc. Natl. Acad. Sci. USA 115 (2), 313-318 (2018). DOI: 10.1073/pnas.1706846115

Michael S. Little, Samuel J. Pellock, William G. Walton, Ashutosh Tripathy, Matthew R. Redinbo, "Structural basis for the regulation of [beta]-glucuronidase expression by human gut Enterobacteriaceae," Proc. Natl. Acad. Sci. USA 115 (2), E152-E161 (2018). DOI: 10.1073/pnas.1716241115

Tao Che, Susruta Majumdar, Saheem A. Zaidi, Pauline Ondachi, John D. McCorvy, Sheng Wang, Philip D. Mosier, Rajendra Uprety, Eyal Vardy, Brian E. Krumm, Gye Won Han, Ming-Yue Lee, Els Pardon, Jan Steyaert, Xi-Ping Huang, Ryan T. Strachan, Alexandra R. Tribo, Gavril W. Pasternak, F. Ivy Carroll, Raymond C. Stevens, Vadim Cherezov, Vsevolod Katritch, Daniel Wacker, Bryan L. Roth, "Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor," Cell 172 (1-2), 55-67 (2018). DOI: 10.1016/j.cell.2017.12.011

Tengchuan Jin, Mo Huang, Jiansheng Jiang, Patrick Smith, Tsan Sam Xiao, "Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction," PLoS One 13 (1), e0190547-1-e0190547-11 (2018). DOI: https://doi.org/10.1371/journal.pone.0190547

Aleksandra E. Sikora, Igor H. Wierzbicki, Ryszard A. Zielke, Rachael F. Ryner, Konstantin V. Korotkov, Susan K. Buchanan, Nicholas Noinaj, "Structural and functional insights into the role of BamD and BamE within the [beta]-barrel assembly machinery in Neisseria gonorrhoeae," J. Biol. Chem. 293 (4), 1106-1119 (2018). DOI: 10.1074/jbc.RA117.000437

Matthew T. Eddy, Ming-Yue Lee, Zhan-Guo Gao, Kate L. White, Tatiana Didenko, Reto Horst, Martin Audet, Pawel Stanczak, Kyle M. McClary, Gye Won Han, Kenneth A. Jacobson, Raymond C. Stevens, Kurt Wüthrich, "Allosteric Coupling of Drug Binding and Intracellular Signaling in the A[subscript 2A] Adenosine Receptor," Cell 172 (1-2), 68-80 (2018). DOI: 10.1016/j.cell.2017.12.004

Yao Fang, Xiao Xiao, Shu-Xing Li, Aaron Wolfe, Xiaojiang S. Chen, "Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA," J. Mol. Biol. 430 (1), 87-101 (2018). DOI: 10.1016/j.jmb.2017.11.007

Walter A. Bogdanoff, Edmundo I. Perez, Tomás López, Carlos F. Arias, Rebecca M. DuBois, "Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design," J. Virol. 92 (1), e01546-1-e01546-17 (2018). DOI: 10.1128/JVI.01546-17

Guennadi Kozlov, Kathy Wong, Wenxuan Wang, Pavol Skubák, Juliana Muñoz-Escobar, Yue Liu, Nadeem Siddiqui, Navraj S. Pannu, Kalle Gehring, "Ankyrin repeats as a dimerization module," Biochem. Biophys. Res. Commun. 495 (1), 1002-1007 (2018). DOI: 10.1016/j.bbrc.2017.11.135

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Melinda M. Diver, Leanne Pedi, Akiko Koide, Shohei Koide, Stephen B. Long, "Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT," Nature 553, 526-529 (2018). DOI: 10.1038/nature25439

Megan P.D. Zahniser, Shreenath Prasad, Malea M. Kneen, Cheryl A. Kreinbring, Gregory A. Petsko, Dagmar Ringe, Michael J. McLeish, "Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily," Protein Eng. Des. Sel. 30 (3), 271-278 (2017). DOI: https://doi.org/10.1093/protein/gzx015

Xiao Xiao, Hanjing Yang, Vagan Arutiunian, Yao Fang, Guillaume Besse, Cherie Morimoto, Brett Zirkle, Xiaojiang S. Chen, "Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation," Nucleic Acids Res. 45 (12), 7494-7506 (2017). DOI: 10.1093/nar/gkx362 Cited 29 times

Renata Z. Jurkowska, Su Qin, Goran Kungulovski, Wolfram Tempel, Yanli Liu, Pavel Bashtrykov, Judith Stiefelmaier, Tomasz P. Jurkowski, Srikanth Kudithipudi, Sara Weirich, Raluca Tamas, Hong Wu, Ludmila Dombrovski, Peter Loppnau, Richard Reinhardt, Jinrong Min, Albert Jeltsch, "H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1," Nat. Commun. 8, 2057-1-2057-13 (2017). DOI: 10.1038/s41467-017-02259-9

Ryan G. Walker, Magdalena Czepnik, Erich J. Goebel, Jason C. McCoy, Ana Vujic, Miook Cho, Juhyun Oh, Senem Aykul, Kelly L. Walton, Gauthier Schang, Daniel J. Bernard, Andrew P. Hinck, Craig A. Harrison, Erik Martinez-Hackert, Amy J. Wagers, Richard T. Lee, Thomas B. Thompson, "Structural basis for potency differences between GDF8 and GDF11," BMC Biology 15, 19-1-19-22 (2017). DOI: 10.1186/s12915-017-0350-1 Cited 71 times

Brian J. McMillan, Brandon Zimmerman, Emily D. Egan, Michael Lofgren, Xiang Xu, Anthony Hesser, Stephen C. Blacklow, "Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations," Glycobiology 27 (8), 777-786 (2017). DOI: 10.1093/glycob/cwx020 Cited 35 times

Zinaida Polonskaya, Shenglou Deng, Anita Sarkar, Lisa Kain, Marta Comellas-Aragones, Craig S. McKay, Katarzyna Kaczanowska, Marie Holt, Ryan McBride, Valle Palomo, Kevin M. Self, Seth Taylor, Adriana Irimia, Sanjay R. Mehta, Jennifer M. Dan, Matthew Brigger, Shane Crotty, Stephen P. Schoenberger, James C. Paulson, Ian A. Wilson, Paul B. Savage, M.G. Finn, Luc Teyton, "T cells control the generation of nanomolar-affinity anti-glycan antibodies," J. Clin. Invest. 127 (4), 1491-1504 (2017). DOI: 10.1172/JCI91192 Cited 49 times

Alayna M. George Thompson, Cristina V. Iancu, Kenneth E. Neet, John V. Dean, Jun-yong Choe, "Differences in salicylic acid glucose conjugations by UGT74F1 and UGT74F2 from Arabidopsis thaliana," Sci. Rep. 7, 46629-1-46629-11 (2017). DOI: 10.1038/srep46629 Cited 78 times

Ralph Pantophlet, Nino Trattnig, Sasha Murrell, Naiomi Lu, Dennis Chau, Caitlin Rempel, Ian A. Wilson, Paul Kosma, "Bacterially Derived Synthetic Mimetics of Mammalian Oligomannose Prime Antibody Responses That Neutralize Hiv Infectivity," Nat. Commun. 8 (1), 1601-1-1601-12 (2017). DOI: 10.1038/s41467-017-01640-y

Ruslan Sanishvili, Robert F. Fischetti, "Applications of X-Ray Micro-Beam for Data Collection," Protein Crystallography: Methods and Protocols, A. Wlodawer, Z. Dauter, M. Jaskolski, eds., Humana Press, 2017, 219 - 238. DOI: 10.1007/978-1-4939-7000-1_9

Chun-Liang Chen, James C. Mermoud, Lake N. Paul, Calvin Nicklaus Steussy, Cynthia V. Stauffacher, "Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis," J. Biol. Chem. 292 (52), 21340-21351 (2017). DOI: 10.1074/jbc.M117.802223

Kelly A. Manthei, Joomi Ahn, Alisa Glukhova, Wenmin Yuan, Christopher Larkin, Taylor D. Manett, Louise Chang, James A. Shayman, Milton J. Axley, Anna Schwendeman, John J.G. Tesmer, "A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I," J. Biol. Chem. 292, 20313-20327 (2017). DOI: 10.1074/jbc.M117.802736

Matthew R. Jensen, Brandon R. Goblirsch, James K. Christenson, Morgan A. Esler, Fatuma A. Mohamed, Lawrence P. Wackett, Carrie M. Wilmot, "OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis," Biochem. J. 474 (23), 3871-3886 (2017). DOI: 10.1042/BCJ20170642

Jayakanth Kankanala, Karen A. Kirby, Andrew D. Huber, Mary C. Casey, Daniel J. Wilson, StefanG. Sarafianos, Zhengqiang Wang, "Design, Synthesis and Biological Evaluations of N-Hydroxy Thienopyrimidine-2,4-Diones as Inhibitors of Hiv Reverse Transcriptase-Associated Rnase H," Eur. J. Med. Chem. 141, 149-161 (2017). DOI: 10.1016/j.ejmech.2017.09.054

Erik H. Klontz, Adam D. Tomich, Sebastian Gunther, Justin A. Lemkul, Daniel Deredge, Zach Silverstein, JoAnna F. Shaw, Christi McElheny, Yohei Doi, Patrick L. Wintrode, Alexander D. MacKerell, Nicholas Sluis-Kremer, Eric J. Sundberg, "Structure and Dynamics of Fosa-Mediated Fosfomycin Resistance in Klebsiella Pneumoniae and Escherichia Coli," Antimicrob. Agents Ch. 61 (11), e01572-1-e01572-13 (2017). DOI: 10.1128/AAC.01572-17

Ryan P. Emptage, Megan J. Schoenberger, Kathryn M. Ferguson, Ronen Marmorstein, "Intramolecular Autoinhibition of Checkpoint Kinase 1 Is Mediated by Conserved Basic Motifs of the C-Terminal Kinase-Associated 1 Domain," J. Biol. Chem. 292 (46), 19024-19033 (2017). DOI: 10.1074/jbc.M117.811265

Meredith A. Skiba, Andrew P. Sikkema, Nathan A. Moss, Collin L. Tran, Rebecca M. Sturgis, Lena Gerwick, William H. Gerwick, David H. Sherman, Janet L. Smith, "A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin a Polyketide Starter Unit," ACS Chem. Biol. 12 (12), 3039-3048 (2017). DOI: 10.1021/acschembio.7b00746

Hee-Won Park, Zhujun Ma, Haizhong Zhu, Shimin Jiang, Robert C. Robinson, Sharyn A. Endow, "Structural Basis of Small Molecule Atpase Inhibition of a Human Mitotic Kinesin Motor Protein," Sci. Rep. 7, 15121-1-15121-12 (2017). DOI: 10.1038/s41598-017-14754-6

Elise Landais, Ben Murrell, Bryan Briney, Sasha Murrell, Kimmo Rantalainen, Zachary T. Berndsen, Alejandra Ramos, Lalinda Wickramsingh, Melissa Laird Smith, Kernal Eren, Natalia de Val, Mengyu Wu, Audrey Cappelletti , Jeffrey Umotoy, Yolanda Lie, Terri Wrin, Paul Algate, Po-Ying Chan-Hui , Etienne Karita, Andrew B. Ward, Ian Wilson, Dennis R. Burton, Davey Smith, Sergei L. Kosakovsky Pond, Pascal Poignard, "Hiv Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage," Immunity 47 (5), 990-1003 (2017). DOI: 10.1016/j.immuni.2017.11.002

Christopher D. Radka, Dongquan Chen, Lawrence J. DeLucas, Stephen G. Aller, "The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal," Acta Crystallogr. D 73 (11), 921-939 (2017). DOI: 10.1107/S2059798317015236

Jiansheng Jiang, Kannan Natarajan, Lisa F. Boyd, Giora I. Morozov, Michael G. Mage, David H. Margulies, "Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation," Science 358, 1064-1068 (2017). DOI: 10.1126/science.aao5154

David Oyen, Jonathan L. Torres, Ulrike Wille-Reece, Christian F. Ockenhouse, Daniel Emerling, Jacob Glanville, Wayne Volkmuth, Yevel Flores-Garcia, Fidel Zavala, Andrew B. Ward, C. Richter King, Ian A. Wilson, "Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein," Proc. Natl. Acad. Sci. USA 114 (48), E10438-E10445 (2017). DOI: 10.1073/pnas.1715812114

Siobhan M.Wong King Yuen, Marta Campiglio, Ching-Chieh Tung, Bernhard E. Flucher, Filip Van Petegem, "Structural insights into binding of STAC proteins to voltage-gated calcium channels," Proc. Natl. Acad. Sci. USA 114 (45), E9520-E9528 (2017). DOI: 10.1073/pnas.1708852114

Bernard C. Collins, Robin J. Gunn, Tanya R. McKitrick, Richard D. Cummings, Max D. Cooper, Brantley R. Herrin, Ian A. Wilson, "Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates," Structure 25 (11), 1667-1678 (2017). DOI: 10.1016/j.str.2017.09.003

Aaron M. Marcella, Sannie J. Culbertson, Michael A. Shogren-Knaak, Adam W. Barb, "Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex," J. Mol. Biol. 429 (23), 3763-3775 (2017). DOI: 10.1016/j.jmb.2017.10.015

Jennifer A. Bohn, Keyur Thummar, Ashley York, Alice Raymond, W. Clay Brown, Paul D. Bieniasz, Theodora Hatziioannou, Janet L. Smith, "APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA," Nat. Commun. 8, 1021-1-1021-9 (2017). DOI: 10.1038/s41467-017-01309-6

Brian G. Pierce, Elisabeth N. Boucher, Kurt H. Piepenbrink, Monir Ejemel, Chelsea A. Rapp, William D. Thomas Jr., Eric J. Sundberg, Zhiping Weng, Yang Wang, "Structure-Based Design of Hepatitis C Virus Vaccines That Elicit Neutralizing Antibody Responses to a Conserved Epitope," J. Virol. 91 (20), e01032-1-e01032-17 (2017). DOI: 10.1128/JVI.01032-17

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Jian Liu, Carrie Hiser, Shelagh Ferguson-Miller, "Role of Conformational Change and K-Path Ligands in Controlling Cytochrome C Oxidase Activity," Biochem. Soc. T. 45 (5), 1087-1095 (2017). DOI: 10.1042/BST20160138

Andrew J. Mitchell, Noah P. Dunham, Ryan J. Martinie, Jonathan A. Bergman, Christopher J. Pollock, Kai Hu, Benjamin D. Allen, Wei-chen Chang, Alexey Silakov, J. Martin Bollinger Jr., Carsten Krebs, Amie K. Boal, "Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase," J. Am. Chem. Soc. 139 (39), 13830-13836 (2017). DOI: 10.1021/jacs.7b07374

Nicholas C. Wu, Seth J. Zost, Andrew J. Thompson, David Oyen, Corwin M. Nycholat, Ryan McBride, James C. Paulson, Scott E. Hensley, Ian A. Wilson, "A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine," PLoS Patho. 13 (10), e1006682-1-e1006682-17 (2017). DOI: 10.1371/journal.ppat.1006682

Daniel M. Freed, Nicholas J. Bessman, Anatoly Kiyatkin, Emanuel Salazar-Cavazos, Patrick O. Byrne, Jason O. Moore, Christopher C. Valley, Kathryn M. Ferguson, Daniel J. Leahy, Diane S. Lidke, Mark A. Lemmon, "EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics," Cell 171 (3), 683-695 (2017). DOI: 10.1016/j.cell.2017.09.017 Cited 195 times

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Javier Guenaga, Fernando Garces, Natalia de Val, Robyn L. Stanfield, Viktoriya Dubrovskaya, Brett Higgins, Barbara Carrette, Andrew B. Ward, Ian A. Wilson, Richard T. Wyatt, "Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein," Immunity 46 (5), 792-803 (2017). DOI: 10.1016/j.immuni.2017.04.014 Cited 62 times

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Yamei Yu, Thomas Schürpf, Timothy A. Springer, "How Natalizumab Binds and Antagonizes [alpha subscript 4] Integrins," J. Biol. Chem. 288 (45), 32314-32325 (2013). DOI: 10.1074/jbc.M113.501668 Cited 57 times

Mehmet Sen, Koichi Yuki, Timothy A. Springer, "An internal ligand-bound, metastable state of a leukocyte integrin, [alpha subscript x beta subscript 2]," J. Cell Biol. 203 (4), 629 (2013). DOI: 10.1083/jcb.201308083 Cited 68 times

Hong Wu, Alena Siarheyeva, Hong Zeng, Robert Lam, Aiping Dong, Xian-Hui Wu, Yanjun Li, Matthieu Schapira, Masoud Vedadi, Jinrong Min, "Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2," FEBS Lett. 587 (23), 3859-3868 (2013). DOI: 10.1016/j.febslet.2013.10.020 Cited 37 times

Sunil Kumar Tewary, Haiyan Zhao, Weiran Shen, Jianming Qiu, Liang Tang, "Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human Bocavirus," J. Virol. 87 (21), 11487-11493 (2013). DOI: 10.1128/JVI.01770-13 Cited 23 times

Kenneth D. Clevenger, Rui Wu, Joyce A.V. Er, Dali Liu, Walter Fast, "Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme," ACS Chem. Biol. 8 (10), 2192-2200 (2013). DOI: 10.1021/cb400345h Cited 30 times

Michael Lofgren, Markos Koutmos, Ruma Banerjee, "Autoinhibition and Signaling by the Switch II Motif in the G-protein Chaperone of a Radical B[subscript 12] Enzyme," J. Biol. Chem. 288, 30980-30989 (2013). DOI: 10.1074/jbc.M113.499970 Cited 12 times

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Fabienne Furt, William J. Allen, Joshua R. Widhalm, Peter Madzelan, Robert C. Rizzo, Gilles Basset, Mark A. Wilson, "Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis," Acta Crystallogr. D 69 (10), 1876-1888 (2013). DOI: 10.1107/S0907444913015771 Cited 7 times

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Cristina V. Iancu, Jamillah Zamoon, Sang Bum Woo, Alexander Aleshin, Jun-yong Choe, "Crystal structure of a glucose/H[superscript +] symporter and its mechanism of action," Proc. Natl. Acad. Sci. USA 110 (44), 17862-17867 (2013). DOI: 10.1073/pnas.1311485110 Cited 95 times

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Haiyan Zhao, Theodore E. Christensen, Yvonne N. Kamau, Liang Tang, "Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage," Proc. Natl. Acad. Sci. USA 110 (20), 8075-8080 (2013). DOI: 10.1073/pnas.1301133110 Cited 51 times

Kap Lim, Liudmila Kulakova, Andrey Galkin, Osnat Herzberg, "Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP," PLoS One 8 (5), e64004-1-e64004-7 (2013). DOI: 10.1371/journal.pone.0064004 Cited 4 times

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Tengchuan Jin, Mo Huang, Patrick Smith, Jiansheng Jiang, T. Sam Xiao, "The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces," Acta Crystallogr. F 69 (5), 482-487 (2013). DOI: 10.1107/S1744309113010075 Cited 12 times

Greg A. Snyder, Christine Cirl, Jiansheng Jiang, Kang Chen, Anna Waldhuber, Patrick Smith, Franziska Römmler, Nathaniel Snyder, Theresa Fresquez, Susanne Dürr, Nico Tjandra, Thomas Miethke, Tsan Sam Xiao, "Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli," Proc. Natl. Acad. Sci. USA 110 (17), 6985-6990 (2013). DOI: 10.1073/pnas.1215770110 Cited 68 times

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Pavel Plevka, Rushika Perera, Moh Lan Yap, Jane Cardosa, Richard J. Kuhn, Michael G. Rossmann, "Structure of human enterovirus 71 in complex with a capsid-binding inhibitor," Proc. Natl. Acad. Sci. USA 110 (14), 5463-5467 (2013). DOI: 10.1073/pnas.1222379110 Cited 60 times

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Christoph Bieniossek, Tsuyoshi Imasaki, Yuichiro Takagi, Imre Berger, "MultiBac: expanding the research toolbox for multiprotein complexes," Trends Biochem. Sci. 37 (2), 49-57 (2012). DOI: 10.1016/j.tibs.2011.10.005 Cited 161 times

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Eun Young Yu, Jia Sun, Ming Lei, Neal F. Lue, "Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70," Mol. Cell Biol. 32 (1), 186-198 (2012). DOI: 10.1128/MCB.05875-11 Cited 26 times

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Siyang Sun, Song Gao, Kiran Kondabagil, Ye Xiang, Michael G. Rossmann, Venigalla B. Rao, "Structure and function of the small terminase component of the DNA packaging machine in T4-like bacteriophages," Proc. Natl. Acad. Sci. USA 109 (3), 817-822 (2012). DOI: 10.1073/pnas.1110224109 Cited 71 times

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Peder Cedervall, "Victor A. Bloomfield Fellowship," (2011).

Brandon Goblirsch, "Pauling Poster Prize," (2011).

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Anastasia A. Aksyuk, Lidia P. Kurochkina, Andrei Fokine, Farhad Forouhar, Vadim V. Mesyanzhinov, Liang Tong, Michael G. Rossmann, "Structural Conservation of the Myoviridae Phage Tail Sheath Protein Fold," Structure 19 (12), 1885-1894 (2011). DOI: 10.1016/j.str.2011.09.012 Cited 35 times

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Ismael Alicea, Jonathan S. Marvin, Aleksandr E. Miklos, Andrew D. Ellington, Loren L. Looger, Eric R. Schreiter, "Structure of the Escherichia coli Phosphonate Binding Protein PhnD and Rationally Optimized Phosphonate Biosensors," J. Mol. Biol. 414 (3), 356-369 (2011). DOI: 10.1016/j.jmb.2011.09.047 Cited 49 times

Robyn L. Stanfield, Jean-Philippe Julien, Robert Pejchal, Johannes S. Gach, Michael B. Zwick, Ian A. Wilson, "Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope," J. Mol. Biol. 414 (3), 460-476 (2011). DOI: 10.1016/j.jmb.2011.10.014 Cited 19 times

Tushar K. Maiti, Michelle Permaul, David A. Boudreaux, Christina Mahanic, Sarah Mauney, Chittaranjan Das, "Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme," FEBS J. 278 (24), 4917-4926 (2011). DOI: 10.1111/j.1742-4658.2011.08393.x Cited 34 times

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Srinivas Somarowthu, Heather R. Brodkin, J. Alejandro D’Aquino, Dagmar Ringe, Mary Jo Ondrechen, Penny J. Beuning, "A Tale of Two Isomerases: Compact versus Extended Active Sites in Ketosteroid Isomerase and Phosphoglucose Isomerase," Biochemistry-US 50 (43), 9283-9295 (2011). DOI: 10.1021/bi201089v Cited 29 times

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Claudiu M. Nelersa, Brad J. Schmier, Arun Malhotra, "Purification and crystallization of Bacillus subtilis NrnA, a novel enzyme involved in nanoRNA degradation," Acta Crystallogr. F 67 (10), 1235-1238 (2011). DOI: 10.1107/S1744309111026509 Cited 4 times

Brian Bae, Ryan E. Cobb, Matthew A. DeSieno, Huimin Zhao, Satish K. Nair, "New N-Acetyltransferase Fold in the Structure and Mechanism of the Phosphonate Biosynthetic Enzyme FrbF," J. Biol. Chem. 286 (41), 36132-36141 (2011). DOI: 10.1074/jbc.M111.263533 Cited 8 times

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Aram Chang, Shanteri Singh, Kate E. Helmich, Randal D. Goff, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr., "Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity," Proc. Natl. Acad. Sci. USA 108 (43), 17649-17654 (2011). DOI: 10.1073/pnas.1108484108 Cited 41 times

Nafez Abu Tarboush, Lyndal M.R. Jensen, Erik T. Yukl, Jiafeng Geng, Aimin Liu, Carrie M. Wilmot, Victor L. Davidson, "Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis," Proc. Natl. Acad. Sci. USA 108 (41), 16956-16961 (2011). DOI: 10.1073/pnas.1109423108 Cited 55 times

David B. Sauer, Weizhong Zeng, Srinivasan Raghunathan, Youxing Jiang, "Protein interactions central to stabilizing the K[superscript +] channel selectivity filter in a four-sited configuration for selective K[superscript +] permeation," Proc. Natl. Acad. Sci. USA 108 (40), 16634-16639 (2011). DOI: 10.1073/pnas.1111688108 Cited 36 times

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Paola Sette, Ruiling Mu, Vincent Dussupt, Jiansheng Jiang, Greg Snyder, Patrick Smith, Tsan Sam Xiao, Fadila Bouamr, "The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release," Structure 19 (10), 1485-1495 (2011). DOI: 10.1016/j.str.2011.07.016 Cited 22 times

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Kimihisa Yoshida, Hyuk-Soo Seo, Erik W. Debler, Günter Blobel, André Hoelz, "Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex," Proc. Natl. Acad. Sci. USA 108 (40), 16571-16576 (2011). DOI: 10.1073/pnas.1112846108 Cited 49 times

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Pierre Aller, Stéphanie Duclos, Susan S. Wallace, Sylvie Doublié, "A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex," J. Mol. Biol. 412 (1), 22-34 (2011). DOI: 10.1016/j.jmb.2011.07.007 Cited 25 times

Michael L. Oldham, Jue Chen, "Snapshots of the maltose transporter during ATP hydrolysis," Proc. Natl. Acad. Sci. USA 108 (37), 15152-15156 (2011). DOI: 10.1073/pnas.1108858108 Cited 156 times

Sulochanadevi Baskaran, Vimbai M. Chikwana, Christopher J. Contreras, Keri D. Davis, Wayne A. Wilson, Anna A. DePaoli-Roach, Peter J. Roach, Thomas D. Hurley, "Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen," J. Biol. Chem. 286 (39), 33999-34006 (2011). DOI: 10.1074/jbc.M111.264531 Cited 24 times

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Mark C. Hilgart, Ruslan Sanishvili, Craig M. Ogata, Michael Becker, Nagarajan Venugopalan, Sergey Stepanov, Oleg Makarov, Janet L. Smith, Robert F. Fischetti, "Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals," J. Synchrotron Rad. 18 (5), 717-722 (2011). DOI: 10.1107/S0909049511029918 Cited 52 times

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Pedro Brugarolas, Erica M. Duguid, Wen Zhang, Catherine B. Poor, Chuan He, "Structural and biochemical characterization of N[superscript 5]-carboxyaminoimidazole ribonucleotide synthetase and N[superscript 5]-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus," Acta Crystallogr. D 67 (8), 707-715 (2011). DOI: 10.1107/S0907444911023821 Cited 9 times

Andrei Fokine, Mohammad Z. Islam, Zhihong Zhang, Valorie D. Bowman, Venigalla B. Rao, Michael G. Rossmann, "Structure of the Three N-Terminal Immunoglobulin Domains of the Highly Immunogenic Outer Capsid Protein from a T4-Like Bacteriophage," J. Virol. 85 (16), 8141-8148 (2011). DOI: 10.1128/JVI.00847-11 Cited 52 times

Ning Shi, Weizhong Zeng, Sheng Ye, Yang Li, Youxing Jiang, "Crucial Points within the Pore as Determinants of K[superscript +] Channel Conductance and Gating," J. Mol. Biol. 411 (1), 27-35 (2011). DOI: 10.1016/j.jmb.2011.04.058 Cited 16 times

Monica Ilies, Luigi Di Costanzo, Daniel P. Dowling, Katherine J. Thorn, David W. Christianson, "Binding of [alpha, alpha]-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design," J. Med. Chem. 54 (15), 5432-5443 (2011). DOI: 10.1021/jm200443b Cited 58 times

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Hiroyuki Tanaka, Miki Senda, Nagarajan Venugopalan, Atsushi Yamamoto, Toshiya Senda, Tetsuo Ishida, Kihachiro Horiike, "Crystal Structure of a Zinc-dependent d-Serine Dehydratase from Chicken Kidney," J. Biol. Chem. 286 (31), 27548-27558 (2011). DOI: 10.1074/jbc.M110.201160 Cited 22 times

Johanne Le Coq, Partho Ghosh, "Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement," Proc. Natl. Acad. Sci. USA 108 (35), 14649-14652 (2011). DOI: 10.1073/pnas.1105613108 Cited 28 times

Markos Koutmos, Carmen Gherasim, Janet L. Smith, Ruma Banerjee, "Structural Basis of Multifunctionality in a Vitamin B[subscript 12]-processing Enzyme," J. Biol. Chem. 286 (34), 29780-29787 (2011). DOI: 10.1074/jbc.M111.261370 Cited 63 times

Reza Khayat, Nicholas Brunn, Jeffrey A. Speir, John M. Hardham, Robert G. Ankenbauer, Anette Schneemann, John E. Johnson, "The 2.3-Angstrom Structure of Porcine Circovirus 2," J. Virol. 85 (15), 7856-7862 (2011). DOI: 10.1128/JVI.00737-11 Cited 141 times

Sung-il Yoon, Minsun Hong, Ian A Wilson, "An unusual dimeric structure and assembly for TLR4 regulator RP105–MD-1," Nat. Struct. Mol. Biol. 18, 1028-1035 (2011). DOI: 10.1038/nsmb.2106 Cited 59 times

Jennifer Bridwell-Rabb, Andrew M. Winn, David P. Barondeau, "Structure–Function Analysis of Friedreich’s Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex," Biochemistry-US 50 (33), 7265-7274 (2011). DOI: 10.1021/bi200895k Cited 61 times

Tsuyoshi Imasaki, Guillermo Calero, Gang Cai, Kuang-Lei Tsai, Kentaro Yamada, Francesco Cardelli, Hediye Erdjument-Bromage, Paul Tempst, Imre Berger, Guy Lorch Kornberg, Francisco J. Asturias, Roger D. Kornberg, Yuichiro Takagi, "Architecture of the Mediator head module," Nature 475, 240-243 (2011). DOI: 10.1038/nature10162 Cited 90 times

Nicholas Noinaj, Mary A. Bosserman, M. Alexandra Schickli, Grzegorz Piszczek, Madan K. Kharel, Pallab Pahari, Susan K. Buchanan, Jürgen Rohr, "The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis," J. Biol. Chem. 286 (26), 23533-23543 (2011). DOI: 10.1074/jbc.M111.247833 Cited 21 times

Serdar Uysal, Luis G. Cuello, D. Marien Cortes, Shohei Koide, Anthony A. Kossiakoff, Eduardo Perozo, "Mechanism of activation gating in the full-length KcsA K[superscript +] channel," Proc. Natl. Acad. Sci. USA 108 (29), 11896-11899 (2011). DOI: 10.1073/pnas.1105112108 Cited 57 times

Nataliya Nady, Alexander Lemak, John R. Walker, George V. Avvakumov, Michael S. Kareta, Mayada Achour, Sheng Xue, Shili Duan, Abdellah Allali-Hassani, Xiaobing Zuo, Yun-Xing Wang, Christian Bronner, Frédéric Chédin, Cheryl H. Arrowsmith, Sirano Dhe-Paganon, "Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein," J. Biol. Chem. 286 (27), 24300-24311 (2011). DOI: 10.1074/jbc.M111.234104 Cited 152 times

Jinjin Zhang, Kimberly A. McCabe, Charles E. Bell, "Crystal structures of [lamda] exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity," Proc. Natl. Acad. Sci. USA 108 (29), 11872-11877 (2011). DOI: 10.1073/pnas.1103467108 Cited 67 times

Chi-Lin Tsai, Jennifer Bridwell-Rabb, David P. Barondeau, "Friedreich’s Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron–Sulfur Cluster Assembly Complex," Biochemistry-US 50 (29), 6478-6487 (2011). DOI: 10.1021/bi200666h Cited 38 times

Shanteri Singh, Aram Chang, Randal D. Goff, Craig A. Bingman, Sabine Grüschow, David H. Sherman, George N. Phillips, Jr., Jon S. Thorson, "Structural characterization of the mitomycin 7-O-methyltransferase," Proteins 79 (7), 2181-2188 (2011). DOI: 10.1002/prot.23040 Cited 24 times

Xin Liu, David A. Bushnell, Daniel-Adriano Silva, Xuhui Huang, Roger D. Kornberg, "Initiation Complex Structure and Promoter Proofreading," Science 33, 633-637 (2011). DOI: 10.1126/science.1206629 Cited 46 times

Karl E. Zahn, Egor P. Tchesnokov, Matthias Götte, Sylvie Doublié, "Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase," J. Biol. Chem. 286 (28), 25246-25255 (2011). DOI: 10.1074/jbc.M111.248864 Cited 42 times

Theresa Tiefenbrunn, Wei Liu, Ying Chen, Vsevolod Katritch, C. David Stout, James A. Fee, Vadim Cherezov, "High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment," PLoS One 6 (7), e22348-1-e22348-12 (2011). DOI: 10.1371/journal.pone.0022348 Cited 99 times

Qingping Xu, Neil D. Rawlings, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E. Klock, Mark W. Knuth, Mitchell D. Miller, Marc-Andre Elsliger, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites," PLoS One 6 (7), e22013-1-e22013-10 (2011). DOI: 10.1371/journal.pone.0022013 Cited 19 times

Janesh Kumar, Peter Schuck, Mark L. Mayer, "Structure and Assembly Mechanism for Heteromeric Kainate Receptors," Neuron 71 (2), 319-331 (2011). DOI: 10.1016/j.neuron.2011.05.038 Cited 94 times

Natallia Strushkevich, Farrell MacKenzie, Tatyana Cherkesova, Irina Grabovec, Sergey Usanov, Hee-Won Park, "Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system," Proc. Natl. Acad. Sci. USA 108 (25), 10139-10143 (2011). DOI: 10.1073/pnas.1019441108 Cited 218 times

Jiusheng Lin, Mark A. Wilson, "Escherichia coli Thioredoxin-like Protein YbbN Contains an Atypical Tetratricopeptide Repeat Motif and Is a Negative Regulator of GroEL," J. Biol. Chem. 286 (22), 19459-19469 (2011). DOI: 10.1074/jbc.M111.238741 Cited 11 times

Minlong Shi, Jianghai Zhu, Rui Wang, Xing Chen, Lizhi Mi, Thomas Walz, Timothy A. Springer, "Latent TGF-[beta] structure and activation," Nature 474, 343-349 (2011). DOI: 10.1038/nature10152 Cited 702 times

Kyle T. Dolan, Erica M. Duguid, Chuan He, "Crystal Structures of SlyA Protein, a Master Virulence Regulator of Salmonella, in Free and DNA-bound States," J. Biol. Chem. 286 (25), 22178-22185 (2011). DOI: 10.1074/jbc.M111.245258 Cited 68 times

E. Bridie Day, Carole Guillonneau, Stephanie Gras, Nicole L. La Gruta, Dario A.A. Vignali, Peter C. Doherty, Anthony W. Purcell, Jamie Rossjohn, Stephen J. Turner, "Structural basis for enabling T-cell receptor diversity within biased virus-specific CD[superscript 8+] T-cell responses," Proc. Natl. Acad. Sci. USA 108 (23), 9536-9541 (2011). DOI: 10.1073/pnas.1106851108

Jonathan R. Whicher, Galina Florova, Paulina K. Sydor, Renu Singh, Mamoun Alhamadsheh, Gregory L. Challis, Kevin A. Reynolds, Janet L. Smith, "Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor," J. Biol. Chem. 286 (25), 22558-22569 (2011). DOI: 10.1074/jbc.M110.213512 Cited 35 times

Pavel Plevka, Bärbel Kaufmann, Michael G. Rossmann, "Analysis of phases in the structure determination of an icosahedral virus," Acta Crystallogr. D 67 (6), 568-577 (2011). DOI: 10.1107/S090744491101448X Cited 6 times

Kunio S. Misono, John S. Philo, Tsutomu Arakawa, Craig M. Ogata, Yue Qiu, Haruo Ogawa, Howard S. Young, "Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase," FEBS J. 278 (11), 1818-1829 (2011). DOI: 10.1111/j.1742-4658.2011.08083.x Cited 69 times

Michael L. Oldham, Jue Chen, "Crystal Structure of the Maltose Transporter in a Pretranslocation Intermediate State," Science 332, 1202-1205 (2011). DOI: 10.1126/science.1200767 Cited 174 times

Heather R. Brodkin, Walter R.P. Novak, Amy C. Milne, J. Alejandro D’Aquino, N.M. Karabacak, Ilana G. Goldberg, Jeffrey N. Agar, Mark S. Payne, Gregory A. Petsko, Mary Jo Ondrechen, Dagmar Ringe, "Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida," Biochemistry-US 50 (22), 4923-4935 (2011). DOI: 10.1021/bi101761e Cited 40 times

Louis M. Lazar, S. Zoe Fisher, Aaron G. Moulin, Andrey Kovalevsky, Walter R.P. Novak, Paul Langan, Gregory A. Petsko, Dagmar Ringe, "Time-of-flight neutron diffraction study of bovine [gamma]-chymotrypsin at the Protein Crystallography Station," Acta Crystallogr. F 67 (5), 587-590 (2011). DOI: 10.1107/S1744309111009341 Cited 1 times

Qun Wan, Md Faiz Ahmad, James Fairman, Bonnie Gorzelle, María de la Fuente, Chris Dealwis, Michael E. Maguire, "X-Ray Crystallography and Isothermal Titration Calorimetry Studies of the Salmonella Zinc Transporter ZntB," Structure 19 (5), 700-710 (2011). DOI: 10.1016/j.str.2011.02.011 Cited 25 times

Bärbel Kaufmann, Mohamed El-Far, Pavel Plevka, Valorie D. Bowman, Yi Li, Peter Tijssen, Michael G. Rossmann, "Structure of Bombyx mori Densovirus 1, a Silkworm Pathogen," J. Virol. 85 (10), 4691-4697 (2011). DOI: 10.1128/JVI.02688-10 Cited 22 times

Arulandu Arockiasamy, Anup Aggarwal, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site," Protein Sci. 20 (5), 827-833 (2011). DOI: 10.1002/pro.607 Cited 8 times

Wenjun Cui, Jingzhi Li, David Ron, Bingdong Sha, "The structure of the PERK kinase domain suggests the mechanism for its activation," Acta Crystallogr. D 67 (5), 423-428 (2011). DOI: 10.1107/S0907444911006445 Cited 94 times

Brett Spurrier, Jared M. Sampson, Maxim Totrov, Huiguang Li, Timothy O'Neal, Constance Williams, James Robinson, Miroslaw K. Gorny, Susan Zolla-Pazner, Xiang-Peng Kong, "Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120," Structure 19 (5), 691-699 (2011). DOI: 10.1016/j.str.2011.02.012 Cited 20 times

L. Makowski, J. Bardhan, D. Gore, J. Lal, S. Mandava, S. Park, D.J. Rodi, N.T. Ho, C. Ho, R.F. Fischetti, "WAXS Studies of the Structural Diversity of Hemoglobin in Solution," J. Mol. Biol. 408 (5), 909-921 (2011). DOI: 10.1016/j.jmb.2011.02.062 Cited 23 times

Amie K. Boal, Tyler L. Grove, Monica I. McLaughlin, Neela H. Yennawar, Squire J. Booker, Amy C. Rosenzweig, "Structural Basis for Methyl Transfer by a Radical SAM Enzyme," Science 332, 1089-1092 (2011). DOI: 10.1126/science.1205358 Cited 131 times

Sarel J. Fleishman, Timothy A. Whitehead, Damian C. Ekiert, Cyrille Dreyfus, Jacob E. Corn, Eva-Maria Strauch, Ian A. Wilson, David Baker, "Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin," Science 332, 816-821 (2011). DOI: 10.1126/science.1202617 Cited 429 times

Robert N. Kirchdoerfer, Amanda L. Garner, Caralyn E. Flack, Jenny M. Mee, Alexander R. Horswill, Kim D. Janda, Gunnar F. Kaufmann, Ian A. Wilson, "Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody," J. Biol. Chem. 286 (19), 17351-17358 (2011). DOI: 10.1074/jbc.M111.231258 Cited 45 times

Rui Xu, Ian A. Wilson, "Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin," J. Virol. 85 (10), 5172-5182 (2011). DOI: 10.1128/JVI.02430-10 Cited 104 times

Alexei S. Soares, Matthew A. Engel, Richard Stearns, Sammy Datwani, Joe Olechno, Richard Ellson, John M. Skinner, Marc Allaire, Allen M. Orville, "Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures," Biochemistry-US 50 (21), 4399-4401 (2011). DOI: 10.1021/bi200549x Cited 36 times

Nicole Hfer, David Aragao, Joseph A. Lyons, Martin Caffrey, "Membrane Protein Crystallization in Lipidic Mesophases. Hosting Lipid Effects on the Crystallization and Structure of a Transmembrane Peptide," Cryst. Growth Des. 11 (4), 1182-1192 (2011). DOI: 10.1021/cg101384p Cited 18 times

E. Sethe Burgie, Craig A. Bingman, Shin-ichi Makino, Gary E. Wesenberg, Xiaokang Pan, Brian G. Fox, George N. Phillips, Jr., "Structural architecture of Galdieria sulphuraria DCN1L," Proteins 79 (4), 1329-1336 (2011). DOI: 10.1002/prot.22937 Cited 3 times

Jennifer J. Gehret, Liangcai Gu, William H. Gerwick, Peter Wipf, David H. Sherman, Janet L. Smith, "Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: Structure of a Decarboxylating Thioesterase," J. Biol. Chem. 286 (16), 14445-14454 (2011). DOI: 10.1074/jbc.M110.214635 Cited 52 times

Narayanan Veeraraghavan, Abir Ganguly, Jui-Hui Chen, Philip C. Bevilacqua, Sharon Hammes-Schiffer, Barbara L. Golden, "Metal Binding Motif in the Active Site of the HDV Ribozyme Binds Divalent and Monovalent Ions," Biochemistry-US 50 (13), 2672-2682 (2011). DOI: 10.1021/bi2000164 Cited 47 times

Eliana Gonzales-Vigil, Christopher M. Bianchetti, George N. Phillips, Jr., Gregg A. Howe, "Adaptive evolution of threonine deaminase in plant defense against insect herbivores," Proc. Natl. Acad. Sci. USA 108 (14), 5897-5902 (2011). DOI: 10.1073/pnas.1016157108 Cited 62 times

Erik T. Yukl, Brandon R. Goblirsch, Victor L. Davidson, Carrie M. Wilmot, "Crystal Structures of CO and NO Adducts of MauG in Complex with Pre-Methylamine Dehydrogenase: Implications for the Mechanism of Dioxygen Activation," Biochemistry-US 50 (14), 2931-2938 (2011). DOI: 10.1021/bi200023n Cited 18 times

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Gira Bhabha, Jeeyeon Lee, Damian C. Ekiert, Jongsik Gam, Ian A. Wilson, H. Jane Dyson, Stephen J. Benkovic, Peter E. Wright, "A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis," Science 332, 234-238 (2011). DOI: 10.1126/science.1198542 Cited 367 times

Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel, Jason N. Cole, John E. Johnson, Victor Nizet, Partho Ghosh, "Streptococcal M1 protein constructs a pathological host fibrinogen network," Nature 472, 64-68 (2011). DOI: 10.1038/nature09967 Cited 76 times

Fei Xu, Huixian Wu, Vsevolod Katritch, Gye Won Han, Kenneth A. Jacobson, Zhan-Guo Gao, Vadim Cherezov, Raymond C. Stevens, "Structure of an Agonist-Bound Human A[subscript 2A] Adenosine Receptor," Science 332, 322-327 (2011). DOI: 10.1126/science.1202793 Cited 651 times

Farisa Syeda, Rebecca L. Fagan, Matthew Wean, George V. Avvakumov, John R. Walker, Sheng Xue, Sirano Dhe-Paganon, Charles Brenner, "The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1," J. Biol. Chem. 286 (17), 15344-15351 (2011). DOI: 10.1074/jbc.M110.209882 Cited 89 times

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Aram Chang, Shanteri Singh, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr, "Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway," Acta Crystallogr. D 67 (3), 197-203 (2011). DOI: 10.1107/S090744491100360X Cited 13 times

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Mauro Mileni, Joie Garfunkle, Cyrine Ezzili, Benjamin F. Cravatt, Raymond C. Stevens, Dale L. Boger, "Fluoride-Mediated Capture of a Noncovalent Bound State of a Reversible Covalent Enzyme Inhibitor: X-ray Crystallographic Analysis of an Exceptionally Potent [alpha]-Ketoheterocycle Inhibitor of Fatty Acid Amide Hydrolase," J. Am. Chem. Soc. 133 (11), 4092-4100 (2011). DOI: 10.1021/ja110877y Cited 32 times

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Jens C. Krause, Damian C. Ekiert, Terrence M. Tumpey, Patricia B. Smith, Ian A. Wilson, James E. Crowe, Jr., "An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody," Microbiology 2 (1), e00345-1-e00345-10 (2011). DOI: 10.1128/mBio.00345-10 Cited 40 times

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Jia Sun, Yuting Yang, Ke Wan, Ninghui Mao, Tai-Yuan Yu, Yi-Chien Lin, Diane C. DeZwaan, Brian C. Freeman, Jing-Jer Lin, Neal F. Lue, Ming Lei, "Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase [alpha]," Cell Res. 21, 258-274 (2011). DOI: 10.1038/cr.2010.138 Cited 58 times

Shoucheng Du, Laurie Betts, Ruifeng Yang, Haibin Shi, Jason Concel, Jinwoo Ahn, Christopher Aiken, Peijun Zhang, Joanne I. Yeh, "Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding," J. Mol. Biol. 406 (3), 371-386 (2011). DOI: 10.1016/j.jmb.2010.11.027 Cited 46 times

Dianfan Li, Jean Lee, Martin Caffrey, "Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen," Cryst. Growth Des. 11 (2), 530-537 (2011). DOI: 10.1021/cg101378s Cited 41 times

Yong Tang, Marc A. Holbert, Neda Delgoshaie, Hugo Wurtele, Benoît Guillemette, Katrina Meeth, Hua Yuan, Paul Drogaris, Eun-Hye Lee, Chantal Durette, Pierre Thibault, Alain Verreault, Philip A. Cole, Ronen Marmorstein, "Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation," Structure 19 (2), 221-231 (2011). DOI: 10.1016/j.str.2010.12.012 Cited 42 times

X. Edward Zhou, Kelly M. Suino-Powell, Yong Xu, Cee-Wah Chan, Osamu Tanabe, Schoen W. Kruse, Ross Reynolds, James Douglas Engel, H. Eric Xu, "The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor," J. Biol. Chem. 286 (4), 2877-2885 (2011). DOI: 10.1074/jbc.M110.168740 Cited 60 times

Lilia Kaustov, Hui Ouyang, Maria Amaya, Alexander Lemak, Nataliya Nady, Shili Duan, Gregory A. Wasney, Zhihong Li, Masoud Vedadi, Matthieu Schapira, Jinrong Min, Cheryl H. Arrowsmith, "Recognition and Specificity Determinants of the Human Cbx Chromodomains," J. Biol. Chem. 286 (1), 521-529 (2011). DOI: 10.1074/jbc.M110.191411 Cited 212 times

John B. Bruning, Ana C. Murillo, Ofelia Chacon, Raúl G. Barletta, James C. Sacchettini, "Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine," Antimicrob. Agents Ch. 55 (1), 291-301 (2011). DOI: 10.1128/AAC.00558-10 Cited 103 times

Rakesh Joshi, Kwok Ki Ho, Kristen Tenney, Jui-Hui Chen, Barbara L. Golden, Frederick S. Gimble, "Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity," J. Mol. Biol. 405 (1), 185-200 (2011). DOI: 10.1016/j.jmb.2010.10.029 Cited 12 times

Jennifer C. Pai, Jeffrey A. Culver, Jason E. Drury, Rakesh S. Motani, Raquel L. Lieberman, Jennifer A. Maynard, "Conversion of scFv peptide-binding specificity for crystal chaperone development," Protein Eng. Des. Sel. 24 (5), 419-428 (2011). DOI: 10.1093/protein/gzq120 Cited 10 times

David Yin-wei Lin, Jianbo Diao, Daoguo Zhou, Jue Chen, "Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7," J. Biol. Chem. 286 (1), 441-449 (2011). DOI: 10.1074/jbc.M110.167643 Cited 61 times

Mehabaw G. Derebe, Weizhong Zeng, Yang Li, Amer Alam, Youxing Jiang, "Structural studies of ion permeation and Ca[superscript 2+] blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore," Proc. Natl. Acad. Sci. USA 108 (2), 592-597 (2011). DOI: 10.1073/pnas.1013643108 Cited 28 times

Thomas A. Leonard, Bartosz Rozycki, Layla F. Saidi, Gerhard Hummer, James H. Hurley, "Crystal Structure and Allosteric Activation of Protein Kinase C [beta]II," Cell 144 (1), 55-66 (2011). DOI: 10.1016/j.cell.2010.12.013 Cited 152 times

Petra Verdino, Deborah A. Witherden, M. Sharon Ferguson, Adam L. Corper, Andre Schiefner, Wendy L. Havran, Ian A. Wilson, "Molecular Insights into [gamma delta] T Cell Costimulation by an Anti-JAML Antibody," Structure 19 (1), 80-89 (2011). DOI: 10.1016/j.str.2010.10.007 Cited 9 times

Soren G.F. Rasmussen, Hee-Jung Choi, Juan Jose Fung, Els Pardon, Paola Casarosa, Pil Seok Chae, Brian T. DeVree, Daniel M. Rosenbaum, Foon Sun Thian, Tong Sun Kobilka, Andreas Schnapp, Ingo Konetzki, Roger K. Sunahara, Samuel H. Gellman, Alexander Pautsch, Jan Steyaert, William I. Weis, Brian K. Kobilka, "Structure of a nanobody-stabilized active state of the [beta subscript 2] adrenoceptor," Nature 469, 175-180 (2011). DOI: 10.1038/nature09648 Cited 1293 times

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Sudha Chakrapani, Julio F. Cordero-Morales, Vishwanath Jogini, Albert C. Pan, D. Marien Cortes, Benoît Roux, Eduardo Perozo, "On the structural basis of modal gating behavior in K[superscript +] channels," Nat. Struct. Mol. Biol. 18 (1), 67-74 (2011). DOI: 10.1038/nsmb.1968 Cited 59 times

Mehabaw G. Derebe, David B. Sauer, Weizhong Zeng, Amer Alam, Ning Shi, Youxing Jiang, "Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites," Proc. Natl. Acad. Sci. USA 108 (2), 598-602 (2011). DOI: 10.1073/pnas.1013636108 Cited 85 times

Diwahar Narasimhan, Mark R. Nance, Daquan Gao, Mei-Chuan Ko, Joanne Macdonald, Patricia Tamburi, Dan Yoon, Donald M. Landry, James H. Woods, Chang-Guo Zhan, John J.G. Tesmer, Roger K. Sunahara, "Structural analysis of thermostabilizing mutations of cocaine esterase," Protein Eng. Des. Sel. 23 (7), 537-547 (2010). DOI: 10.1093/protein/gzq025 Cited 38 times

Andrei Korostelev, Jianyu Zhu, Haruichi Asahara, Harry F. Noller, "Recognition of the amber UAG stop codon by release factor RF1," EMBO J. 29 (15), 2577-2585 (2010). DOI: 10.1038/emboj.2010.139 Cited 84 times

Can Xie, Jianghai Zhu, Xing Chen, Lizhi Mi, Noritaka Nishida, Timothy A. Springer, "Structure of an integrin with an [alpha]I domain, complement receptor type 4," EMBO J. 29, 666-679 (2010). DOI: 10.1038/emboj.2009.367 Cited 135 times

S. Agarwal, D. Hong, N.K. Desai, M. H.Sazinsky, J.M. Argüello, A.C. Rosenzweig, "Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA," Proteins 78 (11), 2450-2458 (2010). DOI: 10.1002/prot.22753 Cited 16 times

Brandon Goblirsch, "Ross A. Gortner Predoctoral Fellowship," (2010).

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Shenglan Xu, Oleg Makarov, Rich Benn, Derek W. Yoder, Sergey Stepanov, Michael Becker, Stephen Corcoran, Mark Hilgart, Venugopalan Nagarajan, Craig M. Ogata, Sudhir Pothineni, Ruslan Sanishvili, Janet L. Smith, Robert F. Fischetti, "Micro‐Crystallography Developments at GM∕CA‐CAT at the APS," SRI 2009, R. Garrett, I. Gentle, K. Nugent, S. Wilkins, eds., 1234, AIP (2010), 905 - 908. DOI: 10.1063/1.3463363

Laura B. Sheard, Xu Tan, Haibin Mao, John Withers, Gili Ben-Nissan, Thomas R. Hinds, Yuichi Kobayashi, Fong-Fu Hsu, Michal Sharon, John Browse, Sheng Yang He, Josep Rizo, Gregg A. Howe, Ning Zheng, "Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor," Nature 468, 400-405 (2010). DOI: 10.1038/nature09430 Cited 965 times

Brad L. Pentelute, Kalyaneswar Mandal, Zachary P. Gates, Michael R. Sawaya, Todd O. Yeates, Stephen B.H. Kent, "Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography," Chem. Commun. 46 (43), 8174-8176 (2010). DOI: 10.1039/C0CC03148H Cited 39 times

Hao Chen, Chengqi Yi, Jin Zhang, Wenru Zhang, Zhiyun Ge, Cai-Guang Yang, Chuan He, "Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR," EMBO Rep. 11 (9), 685-690 (2010). DOI: 10.1038/embor.2010.96 Cited 38 times

Khawar Sohail Siddiqui, Anne Poljak, Davide De Francisci, Gea Guerriero, Oliver Pilak, Dominic Burg, Mark J. Raftery, Don M. Parkin, Jill Trewhella, Ricardo Cavicchioli, "A chemically modified [alpha]-amylase with a molten-globule state has entropically driven enhanced thermal stability," Protein Eng. Des. Sel. 23 (10), 769-780 (2010). DOI: 10.1093/protein/gzq051 Cited 31 times

Jingwei Huang, Zan Xu, Die Wang, Craig M. Ogata, Krzysztof Palczewski, Xavier Lee, N. Martin Young, "Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses," Glycobiology 20 (12), 1643-1653 (2010). DOI: 10.1093/glycob/cwq118 Cited 7 times

Louise Scharf, Nan-Sheng Li, Andrew J. Hawk, Diana Garzón, Tejia Zhang, Lisa M. Fox, Allison R. Kazen, Sneha Shah, Esmael J. Haddadian, Jenny E. Gumperz, Alan Saghatelian, José D. Faraldo-Gómez, Stephen C. Meredith, Joseph A. Piccirilli, Erin J. Adams, "The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation," Immunity 33 (6), 853-862 (2010). DOI: 10.1016/j.immuni.2010.11.026 Cited 88 times

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Markos Koutmos, Omer Kabil, Janet L. Smith, Ruma Banerjee, "Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine [beta]-synthase," Proc. Natl. Acad. Sci. USA 107 (49), 20958-20963 (2010). DOI: 10.1073/pnas.1011448107 Cited 90 times

Virginie Molle, Gulcin Gulten, Catherine Vilchèze, Romain Veyron-Churlet, Isabelle Zanella-Cléon, James C. Sacchettini, William R. Jacobs, Jr, Laurent Kremer, "Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis," Mol. Microbiol. 78 (6), 1591-1605 (2010). DOI: 10.1111/j.1365-2958.2010.07446.x Cited 52 times

Janesh Kumar, Mark L. Mayer, "Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains," J. Mol. Biol. 404 (4), 680-696 (2010). DOI: 10.1016/j.jmb.2010.10.006 Cited 37 times

Ye Xiang, Ulrich Baxa, Ying Zhang, Alasdair C. Steven, Gentry L. Lewis, James L. Van Etten, Michael G. Rossmann, "Crystal Structure of a Virus-Encoded Putative Glycosyltransferase," J. Virol. 84 (23), 12265-12273 (2010). DOI: 10.1128/JVI.01303-10 Cited 11 times

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Fu-Yang Lin, Chia-I Liu, Yi-Liang Liu, Yonghui Zhang, Ke Wang, Wen-Yih Jeng, Tzu-Ping Ko, Rong Cao, Andrew H.-J. Wang, Eric Oldfield, "Mechanism of action and inhibition of dehydrosqualene synthase," Proc. Natl. Acad. Sci. USA 107 (50), 21337-21342 (2010). DOI: 10.1073/pnas.1010907107 Cited 55 times

Jieqing Zhu, Jianghai Zhu, Ana Negri, Davide Provasi, Marta Filizola, Barry S. Coller, Timothy A. Springer, "Closed headpiece of integrin [alpah]IIb[beta]3 and its complex with an [alpha]IIb[beta]3-specific antagonist that does not induce opening," Blood 116 (23), 5050-5059 (2010). DOI: 10.1182/blood-2010-04-281154 Cited 85 times

Katarina Moravcevic, Jeannine M. Mendrola, Karl R. Schmitz, Yu-Hsiu Wang, David Slochower, Paul A. Janmey, Mark A. Lemmon, "Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids," Cell 143 (6), 966-977 (2010). DOI: 10.1016/j.cell.2010.11.028 Cited 124 times

Bärbel Kaufmann, Matthew R. Vogt, Jaap Goudsmit, Heather A. Holdaway, Anastasia A. Aksyuk, Paul R. Chipman, Richard J. Kuhn, Michael S. Diamond, Michael G. Rossmann, "Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354," Proc. Natl. Acad. Sci. USA 107 (44), 18950-18955 (2010). DOI: 10.1073/pnas.1011036107 Cited 108 times

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Samantha J. Hyde, Brian E. Eckenroth, Brian A. Smith, William A. Eberley, Nicholas H. Heintz, Jane E. Jackman, Sylvie Doublié, "tRNA[superscript His] guanylyltransferase (THG1), a unique 3′-5′ nucleotidyl transferase, shares unexpected structural homology with canonical 5′-3′ DNA polymerases," Proc. Natl. Acad. Sci. USA 107 (47), 20305-20310 (2010). DOI: 10.1073/pnas.1010436107 Cited 46 times

Xiaoyun Su, Vinayak Agarwal, Dylan Dodd, Brian Bae, Roderick I. Mackie, Satish K. Nair, Isaac K.O. Cann, "Mutational Insights into the Roles of Amino Acid Residues in Ligand Binding for Two Closely Related Family 16 Carbohydrate Binding Modules," J. Biol. Chem. 285 (45), 34665-34676 (2010). DOI: 10.1074/jbc.M110.168302 Cited 9 times

Brian R. Bowman, Seongmin Lee, Shuyu Wang, Gregory L. Verdine, "Structure of Escherichia coli AlkA in Complex with Undamaged DNA," J. Biol. Chem. 285 (46), 35783-35791 (2010). DOI: 10.1074/jbc.M110.155663 Cited 19 times

Chengqi Yi, Guifang Jia, Guanhua Hou, Qing Dai, Wen Zhang, Guanqun Zheng, Xing Jian, Cai-Guang Yang, Qiang Cui, Chuan He, "Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase," Nature 468, 330-333 (2010). DOI: 10.1038/nature09497 Cited 114 times

Nafez Abu Tarboush, Lyndal M.R. Jensen, Manliang Feng, Hiroyasu Tachikawa, Carrie M. Wilmot, Victor L. Davidson, "Functional Importance of Tyrosine 294 and the Catalytic Selectivity for the Bis-Fe(IV) State of MauG Revealed by Replacement of This Axial Heme Ligand with Histidine," Biochemistry-US 49 (45), 9783-9791 (2010). DOI: 10.1021/bi101254p Cited 41 times

Ellen Y.T. Chien, Wei Liu, Qiang Zhao, Vsevolod Katritch, Gye Won Han, Michael A. Hanson, Lei Shi, Amy Hauck Newman, Jonathan A. Javitch, Vadim Cherezov, Raymond C. Stevens, "Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist," Science 330, 1091-1095 (2010). DOI: 10.1126/science.1197410 Cited 939 times

Beili Wu, Ellen Y.T. Chien, Clifford D. Mol, Gustavo Fenalti, Wei Liu, Vsevolod Katritch, Ruben Abagyan, Alexei Brooun, Peter Wells, F. Christopher Bi, Damon J. Hamel, Peter Kuhn, Tracy M. Handel, Vadim Cherezov, Raymond C. Stevens, "Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists," Science 330, 1066-1071 (2010). DOI: 10.1126/science.1194396 Cited 1428 times

Bärbel Kaufmann, Valorie D. Bowman, Yi Li, Jozsef Szelei, Peter J. Waddell, Peter Tijssen, Michael G. Rossmann, "Structure of Penaeus stylirostris Densovirus, a Shrimp Pathogen," J. Virol. 84 (21), 11289-11296 (2010). DOI: 10.1128/JVI.01240-10 Cited 36 times

Constantina Bakolitsa, Abhinav Kumar, Dennis Carlton, Mitchell D. Miller, S.Sri Krishna, Polat Abdubek, Tamara Astakhova, Herbert L. Axelrod, Hsiu-Ju Chiu, Thomas Clayton, Marc C. Deller, Lian Duan, Marc-André Elsliger, Julie Feuerhelm, Slawomir K. Grzechnik, Joanna C. Grant, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Piotr Kozbial, David Marciano, Daniel McMullan, Andrew T. Morse, Edward Nigoghossian, Linda Okach, Silvya Oommachen, Jessica Paulsen, Ron Reyes, Christopher L. Rife, Henry J. Tien, Christina V. Trout, Henry van den Bedem, Dana Weekes, Qingping Xu, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism," Acta Crystallogr. F 66 (10), 1205-1210 (2010). DOI: 10.1107/S1744309109023689 Cited 2 times

Katie J. Doores, Zara Fulton, Vu Hong, Mitul K. Patel, Christopher N. Scanlan, Mark R. Wormald, M.G. Finn, Dennis R. Burton, Ian A. Wilson, Benjamin G. Davis, "A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity," Proc. Natl. Acad. Sci. USA 107 (40), 17107-17112 (2010). DOI: 10.1073/pnas.1002717107 Cited 80 times

Paul A. Del Rizzo, Jean-François Couture, Lynnette M.A. Dirk, Bethany S. Strunk, Marijo S. Roiko, Joseph S. Brunzelle, Robert L. Houtz, Raymond C. Trievel, "SET7/9 Catalytic Mutants Reveal the Role of Active Site Water Molecules in Lysine Multiple Methylation," J. Biol. Chem. 285 (41), 31849-31858 (2010). DOI: 10.1074/jbc.M110.114587 Cited 48 times

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Robert Pejchal, Laura M. Walker, Robyn L. Stanfield, Sanjay K. Phogat, Wayne C. Koff, Pascal Poignard, Dennis R. Burton, Ian A. Wilson, "Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1," Proc. Natl. Acad. Sci. USA 107 (25), 11483-11488 (2010). DOI: 10.1073/pnas.1004600107 Cited 164 times

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Fumin Shi, Shannon E. Telesco, Yingting Liu, Ravi Radhakrishnan, Mark A. Lemmon, "ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation," Proc. Natl. Acad. Sci. USA 107 (17), 7692-7697 (2010). DOI: 10.1073/pnas.1002753107 Cited 344 times

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Lyndal M.R. Jensen, Ruslan Sanishvili, Victor L. Davidson, Carrie M. Wilmot, "In Crystallo Posttranslational Modification Within a MauG/Pre–Methylamine Dehydrogenase Complex," Science 327, 1392-1394 (2010). DOI: 10.1126/science.1182492 Cited 104 times

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Hee-Jung Choi, Julia C. Gross, Sabine Pokutta, William I. Weis, "Interactions of Plakoglobin and [beta]-Catenin with Desmosomal Cadherins BASIS OF SELECTIVE EXCLUSION OF [alpha]- AND [beta]-CATENIN FROM DESMOSOMES," J. Biol. Chem. 284, 31776-31788 (2009). DOI: 10.1074/jbc.M109.047928 Cited 53 times

Erik W. Debler, Roger Müller, Donald Hilvert, Ian A. Wilson, "An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket," Proc. Natl. Acad. Sci. USA 106 (44), 18539-18544 (2009). DOI: 10.1073/pnas.0902700106 Cited 20 times

Junbin Hu, Jingzhi Li, Xinguo Qian, Vlad Denic, Bingdong Sha, "The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion," PLoS One 4 (11), e8061-1-e8061-7 (2009). DOI: 10.1371/journal.pone.0008061 Cited 52 times

Qingan Sun, Gabriel F. Kuty, Arulandu Arockiasamy, Min Xu, Ry Young, James C. Sacchettini, "Regulation of a muralytic enzyme by dynamic membrane topology," Nat. Struct. Mol. Biol. 16, 1192-1194 (2009). DOI: 10.1038/nsmb.1681 Cited 51 times

Markos Koutmos, Supratim Datta, Katherine A. Pattridge, Janet L. Smith, Rowena G. Matthews, "Insights into the reactivation of cobalamin-dependent methionine synthase," Proc. Natl. Acad. Sci. USA 106 (44), 18527-18532 (2009). DOI: 10.1073/pnas.0906132106 Cited 58 times

Jonathan M. Budzik, Catherine B. Poor, Kym F. Faull, Julian P. Whitelegge, Chuan He, Olaf Schneewind, "Intramolecular amide bonds stabilize pili on the surface of bacilli," Proc. Natl. Acad. Sci. USA 106 (47), 19992-19997 (2009). DOI: 10.1073/pnas.0910887106 Cited 62 times

Amie K. Boal, Amy C. Rosenzweig, "Crystal Structures of Cisplatin Bound to a Human Copper Chaperone," J. Am. Chem. Soc. 131 (40), 14196-14197 (2009). DOI: 10.1021/ja906363t Cited 135 times

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Philip D. Kiser, Marcin Golczak, David T. Lodowski, Mark R. Chance, Krzysztof Palczewski, "Crystal structure of native RPE65, the retinoid isomerase of the visual cycle," Proc. Natl. Acad. Sci. USA 106 (41), 17325-17330 (2009). DOI: 10.1073/pnas.0906600106 Cited 117 times

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Yufeng Tong, Wolfram Tempel, Lyudmila Nedyalkova, Farrell MacKenzie, Hee-Won Park, "Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE," PLoS One 4 (10), e7165-1-e7165-9 (2009). DOI: 10.1371/journal.pone.0007165 Cited 23 times

Nina S. Ponomarenko, Liang Li, Antony R. Marino, Valentina Tereshko, Agnes Ostafin, Julia A. Popova, Edward J. Bylina, Rustem F. Ismagilov, James R. Norris, Jr., "Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center," BBA-Biomembranes 1788 (9), 1822-1831 (2009). DOI: 10.1016/j.bbamem.2009.06.006 Cited 7 times

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Diego Alvarado, Daryl E. Klein, Mark A. Lemmon, "ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor," Nature 461, 287-291 (2009). DOI: 10.1038/nature08297 Cited 63 times

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Lijun Liu, Adam J.V. Marwitz, Brian W. Matthews, Shih-Yuan Liu, "Boron Mimetics: 1,2-Dihydro-1,2-azaborines Bind inside a Nonpolar Cavity of T4 Lysozyme," Angew. Chem. Int. Ed. 48 (37), 6817-6819 (2009). DOI: 10.1002/anie.200903390 Cited 97 times

Mauro Mileni, Joie Garfunkle, Jessica K. DeMartino, Benjamin F. Cravatt, Dale L. Boger, Raymond C. Stevens, "Binding and Inactivation Mechanism of a Humanized Fatty Acid Amide Hydrolase by [alpha]-Ketoheterocycle Inhibitors Revealed from Cocrystal Structures," J. Am. Chem. Soc. 131 (30), 10497-10506 (2009). DOI: 10.1021/ja902694n Cited 79 times

Jing Wu, Weishu Bu, Kelly Sheppard, Makoto Kitabatake, Suk-Tae Kwon, Dieter Söll, Janet L. Smith, "Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme," J. Mol. Biol. 391 (4), 703-716 (2009). DOI: 10.1016/j.jmb.2009.06.014 Cited 27 times

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K. Payne, Q. Sun, J. Sacchettini, G.F. Hatfull, "Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase," Mol. Microbiol. 73 (3), 367-381 (2009). DOI: 10.1111/j.1365-2958.2009.06775.x Cited 97 times

Melissa R. Landon, Raquel L. Lieberman, Quyen Q. Hoang, Shulin Ju, Jose M.M. Caaveiro, Susan D. Orwig, Dima Kozakov, Ryan Brenke, Gwo-Yu Chuang, Dmitry Beglov, Sandor Vajda, Gregory A. Petsko, Dagmar Ringe, "Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase," J. Comput. Aided Mol. Des. 23 (8), 491-500 (2009). DOI: 10.1007/s10822-009-9283-2 Cited 60 times

Catherine B. Poor, Peng R. Chen, Erica Duguid, Phoebe A. Rice, Chuan He, "Crystal Structures of the Reduced, Sulfenic Acid, and Mixed Disulfide Forms of SarZ, a Redox Active Global Regulator in Staphylococcus aureus," J. Biol. Chem. 284 (35), 23517-23524 (2009). DOI: 10.1074/jbc.M109.015826 Cited 76 times

Hyuk-Soo Seo, Yingli Ma, Erik W. Debler, Daniel Wacker, Stephan Kutik, Günter Blobel, André Hoelz, "Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex," Proc. Natl. Acad. Sci. USA 106 (34), 14281-14286 (2009). DOI: 10.1073/pnas.0907453106 Cited 60 times

Yiling Fang, Hariharan Jayaram, Tania Shane, Ludmila Kolmakova-Partensky, Fang Wu, Carole Williams, Yong Xiong, Christopher Miller, "Structure of a prokaryotic virtual proton pump at 3.2 Å resolution," Nature 460, 1040-1043 (2009). DOI: 10.1038/nature08201 Cited 186 times

Daniel G. Pellicci, Onisha Patel, Lars Kjer-Nielsen, Siew Siew Pang, Lucy C. Sullivan, Konstantinos Kyparissoudis, Andrew G. Brooks, Hugh H. Reid, Stephanie Gras, Isabelle S. Lucet, Ruide Koh, Mark J. Smyth, Thierry Mallevaey, Jennifer L. Matsuda, Laurent Gapin, James McCluskey, Dale I. Godfrey, Jamie Rossjohn, "Differential Recognition of CD1d-[alpha]-Galactosyl Ceramide by the V[beta]8.2 and V[beta]7 Semi-invariant NKT T Cell Receptors," Immunity 31 (1), 47-59 (2009). DOI: 10.1016/j.immuni.2009.04.018 Cited 184 times

Michael M. Brent, Ayaka Iwata, Juliana Carten, Kehao Zhao, Ronen Marmorstein, "Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus," J. Biol. Chem. 284 (29), 19412-19419 (2009). DOI: 10.1074/jbc.M109.014951 Cited 17 times

J. Alejandro D’Aquino, Andrew R. Denninger, Aaron G. Moulin, Katharine E. D’Aquino, Dagmar Ringe, "Decreased Sensitivity to Changes in the Concentration of Metal Ions as the Basis for the Hyperactivity of DtxR(E175K)," J. Mol. Biol. 390 (1), 112-123 (2009). DOI: 10.1016/j.jmb.2009.05.003 Cited 4 times

Raquel L. Lieberman, J. Alejandro D’aquino, Dagmar Ringe, Gregory A. Petsko, "Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability," Biochemistry-US 48 (22), 4816-4827 (2009). DOI: 10.1021/bi9002265 Cited 119 times

Zhu Wang, X. Edward Zhou, Daniel L. Motola, Xin Gao, Kelly Suino-Powell, Aoife Conneely, Craig Ogata, Kamalesh K. Sharma, Richard J. Auchus, James B. Lok, John M. Hawdon, Steven A. Kliewer, H. Eric Xu, David J. Mangelsdorf, "Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes," Proc. Natl. Acad. Sci. USA 106 (23), 9138-9143 (2009). DOI: 10.1073/pnas.0904064106 Cited 94 times

Anastasia A. Aksyuk, Petr G. Leiman, Mikhail M. Shneider, Vadim V. Mesyanzhinov, Michael G. Rossmann, "The Structure of Gene Product 6 of Bacteriophage T4, the Hinge-Pin of the Baseplate," Structure 17 (6), 800-808 (2009). DOI: 10.1016/j.str.2009.04.005 Cited 25 times

Peng Xie, Craig Streu, Jie Qin, Howard Bregman, Nicholas Pagano, Eric Meggers, Ronen Marmorstein, "The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase," Biochemistry-US 48 (23), 5187-5198 (2009). DOI: 10.1021/bi802067u Cited 64 times

Ling Qin, Jian Liu, Denise A. Mills, Denis A. Proshlyakov, Carrie Hiser, Shelagh Ferguson-Miller, "Redox-Dependent Conformational Changes in Cytochrome c Oxidase Suggest a Gating Mechanism for Proton Uptake," Biochemistry-US 48 (23), 5121-5130 (2009). DOI: 10.1021/bi9001387 Cited 119 times

David A. Jacques, Margaret Streamer, Susan L. Rowland, Glenn F. King, J. Mitchell Guss, J. Trewhella, David B. Langley, "Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state," Acta Crystallogr. D 65 (6), 574-581 (2009). DOI: 10.1107/S090744490901169X Cited 10 times

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Frédérick Faucher, Stéphanie Duclos, Viswanath Bandaru, Susan S. Wallace, Sylvie Doublié, "Crystal Structures of Two Archaeal 8-Oxoguanine DNA Glycosylases Provide Structural Insight into Guanine/8-Oxoguanine Distinction," Structure 17 (5), 703-712 (2009). DOI: 10.1016/j.str.2009.03.007 Cited 15 times

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Jacky Chi Ki Ngo, Kayla Giang, Sutapa Chakrabarti, Chen-Ting Ma, Nhat Huynh, Jonathan C. Hagopian, Pieter C. Dorrestein, Xiang-Dong Fu, Joseph A. Adams, Gourisankar Ghosh, "A Sliding Docking Interaction Is Essential for Sequential and Processive Phosphorylation of an SR Protein by SRPK1," Mol. Cell 29 (5), 563-576 (2008). DOI: 10.1016/j.molcel.2007.12.017 Cited 91 times

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Andrei Fokine, Konstantin A. Miroshnikov, Mikhail M. Shneider, Vadim V. Mesyanzhinov, Michael G. Rossmann, "Structure of the Bacteriophage [phi]KZ Lytic Transglycosylase gp144," J. Biol. Chem. 283 (11), 7242-7250 (2008). DOI: 10.1074/jbc.M709398200 Cited 46 times

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Yong Chen, Yuting Yang, Megan van Overbeek, Jill R. Donigian, Paul Baciu, Titia de Lange, Ming Lei, "A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins," Science 319 (5866), 1092-1096 (2008). DOI: 10.1126/science.1151804 Cited 193 times

Ralf Jauch, Calista Keow Leng Ng, Kumar Singh Saikatendu, Raymond C. Stevens, Prasanna R. Kolatkar, "Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog," J. Mol. Biol. 376 (3), 758-770 (2008). DOI: 10.1016/j.jmb.2007.11.091 Cited 66 times

Min Guo, Michael Ignatov, Karin Musier-Forsyth, Paul Schimmel, Xiang-Lei Yang, "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation," Proc. Natl. Acad. Sci. USA 105 (7), 2331-2336 (2008). DOI: 10.1073/pnas.0712072105 Cited 74 times

Eduard Bitto, Yu Huang, Craig A. Bingman, Shanteri Singh, Jon S. Thorson, George N. Phillips, Jr., "The structure of flavin-dependent tryptophan 7-halogenase RebH," Proteins 70 (1), 289-293 (2008). DOI: 10.1002/prot.21627 Cited 75 times

Margarita Malakhova, Valentina Tereshko, Sung-Young Lee, Ke Yao, Yong-Yeon Cho, Ann Bode, Zigang Dong, "Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2," Nat. Struct. Mol. Biol. 15 (1), 112-113 (2008). DOI: 10.1038/nsmb1347 Cited 39 times

Jianbo Diao, Ying Zhang, Jon M. Huibregtse, Daoguo Zhou, Jue Chen, "Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase," Nat. Struct. Mol. Biol. 15 (1), 65-70 (2008). DOI: 10.1038/nsmb1346 Cited 86 times

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Jason W. Johnston, Nathan P. Coussens, Simon Allen, Jon C.D. Houtman, Keith H. Turner, Anthony Zaleski, S. Ramaswamy, Bradford W. Gibson, Michael A. Apicella, "Characterization of the N-Acetyl-5-neuraminic Acid-binding Site of the Extracytoplasmic Solute Receptor (SiaP) of Nontypeable Haemophilus influenzae Strain 2019," J. Biol. Chem. 283 (2), 855-865 (2008). DOI: 10.1074/jbc.M706603200 Cited 60 times

P.J. Paukstelis, J.-H. Chen, E. Chase, A.M. Lambowitz, B.L. Golden, "Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA," Nature 451 (7174), 94-97 (2008). DOI: 10.1038/nature06413 Cited 69 times

Junyu Xiao, Hengchuan Xia, Jiahai Zhou, Ishara F. Azmi, Brian A. Davies, David J. Katzmann, Zhaohui Xu, "Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway," Dev. Cell 14 (1), 37-49 (2008). DOI: 10.1016/j.devcel.2007.10.013 Cited 87 times

Stephen C. Graham, J. Mitchell Guss, "Complexes of mutants of Escherichia coli aminopeptidase P and the tripeptide substrate ValProLeu," Arch. Biochem. Biophys. 469 (2), 200-208 (2008). DOI: 10.1016/j.abb.2007.10.009 Cited 16 times

Jing-Dong Ye, Valentina Tereshko, John K. Frederiksen, Akiko Koide, Frederic A. Fellouse, Sachdev S. Sidhu, Shohei Koide, Anthony A. Kossiakoff, Joseph A. Piccirilli, "Synthetic antibodies for specific recognition and crystallization of structured RNA," Proc. Natl. Acad. Sci. USA 105 (1), 82-87 (2008). DOI: 10.1073/pnas.0709082105 Cited 97 times

Dali Liu, Pei W. Thomas, Jessica Momb, Quyen Q. Hoang, Gregory A. Petsko, Dagmar Ringe, Walter Fast, "Structure and Specificity of a Quorum-Quenching Lactonase (AiiB) from Agrobacterium tumefaciens," Biochemistry-US 46 (42), 11789-11799 (2007). DOI: 10.1021/bi7012849 Cited 78 times

Siyang Sun, Kiran Kondabagil, Petra M. Gentz, Michael G. Rossmann, Venigalla B. Rao, "The Structure of the ATPase that Powers DNA Packaging into Bacteriophage T4 Procapsids," Mol. Cell 25 (6), 943-949 (2007). DOI: 10.1016/j.molcel.2007.02.013 Cited 99 times

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Christopher D. Fleming, Carol C. Edwards, Stephen D. Kirby, Donald M. Maxwell, Philip M. Potter, Douglas M. Cerasoli, Matthew R. Redinbo, "Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun," Biochemistry-US 46 (17), 5063-5071 (2007). DOI: 10.1021/bi700246n Cited 57 times

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J. Alejandro D'Aquino, Judith R. Lattimer, Andrew Denninger, Katharine E. D'Aquino, Dagmar Ringe, "Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR," Biochemistry-US 46 (42), 11761-11770 (2007). DOI: 10.1021/bi7007883 Cited 8 times

Jill E. Chrencik, Alexei Brooun, Michael I. Recht, George Nicola, Leila K. Davis, Ruben Abagyan, Hans Widmer, Elena B. Pasquale, Peter Kuhn, "Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition," J. Biol. Chem. 282 (50), 36505-36513 (2007). DOI: 10.1074/jbc.M706340200 Cited 50 times

Alexei Savchenko, Michael Proudfoot, Tatiana Skarina, Alexander Singer, Olga Litvinova, Ruslan Sanishvili, Greg Brown, Nickolay Chirgadze, Alexander F. Yakunin, "Molecular Basis of the Antimutagenic Activity of the House-Cleaning Inosine Triphosphate Pyrophosphatase RdgB from Escherichia coli," J. Mol. Biol. 374 (4), 1091-1103 (2007). DOI: 10.1016/j.jmb.2007.10.012 Cited 22 times

Yufeng Tong, Preeti Chugha, Prasanta K. Hota, Rebecca S. Alviani, Mei Li, Wolfram Tempel, Limin Shen, Hee-Won Park, Matthias Buck, "Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain," J. Biol. Chem. 282 (51), 37215-37224 (2007). DOI: 10.1074/jbc.M703800200 Cited 106 times

Christopher M. Bianchetti, Li Yi, Stephen W. Ragsdale, George N. Phillips, Jr., "Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2," J. Biol. Chem. 282 (52), 37624-37631 (2007). DOI: 10.1074/jbc.M707396200 Cited 53 times

Todd W. Geders, Liangcai Gu, Jonathan C. Mowers, Haichuan Liu, William H. Gerwick, Kristina Hakansson, David H. Sherman, Janet L. Smith, "Crystal Structure of the ECH[subscript 2] Catalytic Domain of CurF from Lyngbya majuscula: Insights into a Decarboxylase Involved in Polyketide Chain [beta]-Branching," J. Biol. Chem. 282 (49), 35954-35963 (2007). DOI: 10.1074/jbc.M703921200 Cited 39 times

Koki Makabe, Shude Yan, Valentina Tereshko, Grzegorz Gawlak, Shohei Koide, "[Beta]-strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of [Beta]-strand Pairing," J. Am. Chem. Soc. 129 (47), 14661-14669 (2007). DOI: 10.1021/ja074252c Cited 11 times

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson, Soren G.F. Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Peter Kuhn, William I. Weis, Brian K. Kobilka, Raymond C. Stevens, "High-Resolution Crystal Structure of an Engineered Human [beta subscript 2]-Adrenergic G Protein–Coupled Receptor," Science 318, 1258-1265 (2007). DOI: 10.1126/science.1150577 Cited 2717 times

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Soren G.F. Rasmussen, Hee-Jung Choi, Daniel M. Rosenbaum, Tong Sun Kobilka, Foon Sun Thian, Patricia C. Edwards, Manfred Burghammer, Venkata R.P. Ratnala, Ruslan Sanishvili, Robert F. Fischetti, Gebhard F.X. Schertler, William I. Weis, Brian K. Kobilka, "Crystal structure of the human [beta subscript 2] adrenergic G-protein-coupled receptor," Nature 450, 383-387 (2007). DOI: 10.1038/nature06325 Cited 1578 times

Andrew Robinson, Amy P. Guilfoyle, Stephen J. Harrop, Yan Boucher, H.W. Stokes, Paul M.G. Curmi, Bridget C. Mabbutt, "A putative house-cleaning enzyme encoded within an integron array: 1.8 Å crystal structure defines a new MazG subtype," Mol. Microbiol. 66 (3), 610-621 (2007). DOI: 10.1111/j.1365-2958.2007.05932.x Cited 15 times

Akiko Koide, Valentina Tereshko, Serdar Uysal, Katrina Margalef, Anthony A. Kossiakoff, Shohei Koide, "Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar K[subscript D] of a Single-domain Antibody with a Flat Paratope," J. Mol. Biol. 373 (4), 941-953 (2007). DOI: 10.1016/j.jmb.2007.08.027 Cited 64 times

O.A. Makarov, R. Benn, S. Corcoran, S. Devarapalli, R. Fischetti, M. Hilgart, W.W. Smith, S. Stepanov, S. Xu, "EPICS controlled sample mounting robots at the GM/CA CAT," Nucl. Instrum. Methods A 582 (1), 156-158 (2007). DOI: 10.1016/j.nima.2007.08.096 Cited 5 times

Junyu Xiao, Hengchuan Xia, Kae Yoshino-Koh, Jiahai Zhou, Zhaohui Xu, "Structural Characterization of the ATPase Reaction Cycle of Endosomal AAA Protein Vps4," J. Mol. Biol. 374 (3), 655-670 (2007). DOI: 10.1016/j.jmb.2007.09.067 Cited 44 times

Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson, Jue Chen, "Crystal structure of a catalytic intermediate of the maltose transporter," Nature 450, 515-521 (2007). DOI: 10.1038/nature06264 Cited 419 times

Xin Liu, Ronen Marmorstein, "Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor," Gene Dev. 21 (21), 2711-2716 (2007). DOI: 10.1101/gad.1590607 Cited 70 times

Julio F. Cordero-Morales, Vishwanath Jogini, Anthony Lewis, Valeria Vasquez, D. Marien Cortes, Benoit Roux, Eduardo Perozo, "Molecular driving forces determining potassium channel slow inactivation," Nat. Struct. Mol. Biol. 14 (11), 1062-1069 (2007). DOI: 10.1038/nsmb1309 Cited 196 times

Liangcai Gu, Todd W. Geders, Bo Wang, William H. Gerwick, Kristina Hakansson, Janet L. Smith, David H. Sherman, "GNAT-Like Strategy for Polyketide Chain Initiation," Science 318, 970-974 (2007). DOI: 10.1126/science.1148790 Cited 92 times

Roman Aranda IV, Chad E. Worley, Mengyao Liu, Eduard Bitto, M. Susan Cates, John S. Olson, Benfang Lei, George N. Phillips, Jr., "Bis-methionyl Coordination in the Crystal Structure of the Heme-binding Domain of the Streptococcal Cell Surface Protein Shp," J. Mol. Biol. 374 (2), 374-383 (2007). DOI: 10.1016/j.jmb.2007.08.058 Cited 45 times

Wolfram Tempel, Wael M. Rabeh, Katrina L. Bogan, Peter Belenky, Marzena Wojcik, Heather F. Seidle, Lyudmila Nedyalkova, Tianle Yang, Anthony A. Sauve, Hee-Won Park, Charles Brenner, "Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD[superscript +]," PLoS Biol. 5 (10), e263-1-e263-11 (2007). DOI: 10.1371/journal.pbio.0050263 Cited 112 times

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Pablo D. Jadzinsky, Guillermo Calero, Christopher J. Ackerson, David A. Bushnell, Roger D. Kornberg, "Structure of a Thiol Monolayer-Protected Gold Nanoparticle at 1.1 Å Resolution," Science 318, 430-433 (2007). DOI: 10.1126/science.1148624 Cited 2104 times

Karl E. Zahn, Hassan Belrhali, Susan S. Wallace, Sylvie Doublié, "Caught Bending the A-Rule:  Crystal Structures of Translesion DNA Synthesis with a Non-Natural Nucleotide," Biochemistry-US 46 (37), 10551-10561 (2007). DOI: 10.1021/bi7008807 Cited 41 times

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Ying Zhang, Ye Xiang, James L. Van Etten, Michael G. Rossmann, "Structure and Function of a Chlorella Virus-Encoded Glycosyltransferase," Structure 15 (9), 1031-1039 (2007). DOI: 10.1016/j.str.2007.07.006 Cited 19 times

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Manchi C.M. Reddy, Satheesh K. Palaninathan, Nishant D. Shetty, Joshua L. Owen, Misty D. Watson, James C. Sacchettini, "High Resolution Crystal Structures of Mycobacterium tuberculosis Adenosine Kinase: Insights into the Mechanism and Specificity of this Novel Prokaryotic Enzyme," J. Biol. Chem. 282 (37), 27334-27342 (2007). DOI: 10.1074/jbc.M703290200 Cited 32 times

Brian A. Moore, Howard H. Robinson, Zhaohui Xu, "The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst," J. Mol. Biol. 371 (2), 410-421 (2007). DOI: 10.1016/j.jmb.2007.05.018 Cited 61 times

Jean-Francois Couture, Evys Collazo, Patricia A. Ortiz-Tello, Joseph S. Brunzelle, Raymond C. Trievel, "Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase," Nat. Struct. Mol. Biol. 14 (8), 689-695 (2007). DOI: 10.1038/nsmb1273 Cited 218 times

Matthew H. Sazinsky, Benjamin LeMoine, Maria Orofino, Roman Davydov, Krisztina Z. Bencze, Timothy L. Stemmler, Brian M. Hoffman, Jose M. Arguello, Amy C. Rosenzweig, "Characterization and Structure of a Zn[superscript 2+] and [2Fe-2S]-containing Copper Chaperone from Archaeoglobus fulgidus," J. Biol. Chem. 282 (35), 25950-25959 (2007). DOI: 10.1074/jbc.M703311200 Cited 28 times

Scott A. Lujan, Laura M. Guogas, Heather Ragonese, Steven W. Matson, Matthew R. Redinbo, "Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase," Proc. Natl. Acad. Sci. USA 104 (30), 12282-12287 (2007). DOI: 10.1073/pnas.0702760104 Cited 71 times

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Chi-Lin Tsai, Kuppan Gokulan, Pablo Sobrado, James C. Sacchettini, Paul F. Fitzpatrick, "Mechanistic and Structural Studies of H373Q Flavocytochrome b[subscript 2]:  Effects of Mutating the Active Site Base," Biochemistry-US 46 (26), 7844-7851 (2007). DOI: 10.1021/bi7005543 Cited 17 times

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch," J. Virol. 81 (12), 6700-6708 (2007). DOI: 10.1128/JVI.02817-06 Cited 63 times

Sanghamitra Dey, Zhiqin Hu, Xiao Lan Xu, James C. Sacchettini, Gregory A. Grant, "The Effect of Hinge Mutations on Effector Binding and Domain Rotation in Escherichia coli D-3-Phosphoglycerate Dehydrogenase," J. Biol. Chem. 282 (25), 18418-18426 (2007). DOI: 10.1074/jbc.M701174200 Cited 15 times

Erik W. Debler, Gunnar F. Kaufmann, Robert N. Kirchdoerfer, Jenny M. Mee, Kim D. Janda, Ian A. Wilson, "Crystal structures of a quorum-quenching antibody," J. Mol. Biol. 368 (5), 1392-1402 (2007). DOI: 10.1016/j.jmb.2007.02.081 Cited 25 times

Feng Wang, Robert Langley, Gulcin Gulten, Lei Wang, James C. Sacchettini, "Identification of a Type III Thioesterase Reveals the Function of an Operon Crucial for Mtb Virulence," Chem. Biol. 14 (5), 543-551 (2007). DOI: 10.1016/j.chembiol.2007.04.005 Cited 40 times

M. Rossmann, "Fellow of the American Academy of Microbiology," (2007).

Sergey Stepanov, "Transformation of X-ray Server from a set of WWW-accessed programs into WWW-based library for remote calls from X-ray data analysis software," Thin Solid Films 515 (14), 5700-5703 (2007). DOI: 10.1016/j.tsf.2006.12.011 Cited 3 times

Ling Qin, Denise A. Mills, Carrie Hiser, Anna Murphree, R. Michael Garavito, Shelagh Ferguson-Miller, Jonathan Hosler, "Crystallographic Location and Mutational Analysis of Zn and Cd Inhibitory Sites and Role of Lipidic Carboxylates in Rescuing Proton Path Mutants in Cytochrome c Oxidase," Biochemistry-US 46 (21), 6239-6248 (2007). DOI: 10.1021/bi700173w Cited 34 times

Arati Ramesh, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal Structure of Rsr, an Ortholog of the Antigenic Ro Protein, Links Conformational Flexibility to RNA Binding Activity," J. Biol. Chem. 282 (20), 14960-14967 (2007). DOI: 10.1074/jbc.M611163200 Cited 10 times

C. Gerdts, "The Elizabeth R. Norton Prize at the University of Chicago," (2007).

S. Yan, G. Gawlak, K. Makabe, V. Tereshko, A. Koide, S. Koide, "Hydrophobic Surface Burial Is the Major Stability Determinant of a Flat, Single-layer [beta]-Sheet," J. Mol. Biol. 368 (1), 230-243 (2007). DOI: 10.1016/j.jmb.2007.02.003 Cited 19 times

Korin E. Wheeler, Judith M. Nocek, Deborah A. Cull, Liliya A. Yatsunyk, Amy C. Rosenzweig, Brian M. Hoffman, "Dynamic Docking of Cytochrome b[subscript 5] with Myoglobin and [alpha]-Hemoglobin: Heme-Neutralization “Squares” and the Binding of Electron-Transfer-Reactive Configurations," J. Am. Chem. Soc. 129 (13), 3906-3917 (2007). DOI: 10.1021/ja067598g Cited 38 times

Akiko Koide, Ryan N. Gilbreth, Kaori Esaki, Valentina Tereshko, Shohei Koide, "High-affinity single-domain binding proteins with a binary-code interface," Proc. Natl. Acad. Sci. USA 104 (16), 6632-6637 (2007). DOI: 10.1073/pnas.0700149104 Cited 139 times

Mihwa Lee, Megan J. Maher, J. Mitchell Guss, "Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-­fluoroorotate: catalytic activity is reflected by the crystal form," Acta Crystallogr. F 63 (3), 154-161 (2007). DOI: 10.1107/S1744309107004009 Cited 10 times

Sergei P. Boudko, Richard J. Kuhn, Michael G. Rossmann, "The Coiled-coil Domain Structure of the Sin Nombre Virus Nucleocapsid Protein," J. Mol. Biol. 366 (5), 1538-1544 (2007). DOI: 10.1016/j.jmb.2006.12.046 Cited 30 times

Raquel L. Lieberman, Brandon A. Wustman, Pedro Huertas, Allan C. Powe Jr, Corey W. Pine, Richie Khanna, Michael G. Schlossmacher, Dagmar Ringe, Gregory A. Petsko, "Structure of acid [beta]-glucosidase with pharmacological chaperone provides insight into Gaucher disease," Nat. Chem. Biol. 3 (2), 101-107 (2007). DOI: 10.1038/nchembio850 Cited 190 times

N.P. Coussens, J.C. Mowers, C. McDonald, G. Nunez, S. Ramaswamy, "Crystal structure of the Nod1 caspase activation and recruitment domain," Biochem. Biophys. Res. Commun. 353 (1), 1-5 (2007). DOI: 10.1016/j.bbrc.2006.11.122 Cited 48 times

Vladimir Yu. Torbeev, Stephen B.H. Kent, "Convergent Chemical Synthesis and Crystal Structure of a 203 Amino Acid 'Covalent Dimer' HIV-1 Protease Enzyme Molecule," Angew. Chem. Int. Ed. 43 (10), 1667-1670 (2007). DOI: 10.1002/anie.200604087 Cited 140 times

Feng Wang, Elaine R. Podell, Arthur J. Zaug, Yuting Yang, Paul Baciu, Thomas R. Cech, Ming Lei, "The POT1–TPP1 telomere complex is a telomerase processivity factor," Nature 445, 506-510 (2007). DOI: 10.1038/nature05454 Cited 525 times

S. Ferguson-Miller, "American Association for the Advancement of Science," (2007).

Feng Wang, Robert Langley, Gulcin Gulten, Lynn G. Dover, Gurdyal S. Besra, William R. Jacobs, Jr., James C. Sacchettini, "Mechanism of thioamide drug action against tuberculosis and leprosy," J. Exp. Med. 204 (1), 73-78 (2007). DOI: 10.1084/jem.20062100 Cited 216 times

Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, Sylvie Doublie´, "A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol," Proc. Natl. Acad. Sci. USA 104 (3), 814-818 (2007). DOI: 10.1073/pnas.0606648104 Cited 84 times

Consuelo Garcia-Rodriguez, Raphael Levy, Joseph W. Arndt, Charles M. Forsyth, Ali Razai, Jianlong Lou, Isin Geren, Raymond C. Stevens, James D. Marks, "Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin," Nat. Biotechnol. 25 (1), 107-116 (2007). DOI: 10.1038/nbt1269 Cited 138 times

Matthew Hogg, Pierre Aller, William Konigsberg, Susan S. Wallace, Sylvie Doublie, "Structural and Biochemical Investigation of the Role in Proofreading of a [beta] Hairpin Loop Found in the Exonuclease Domain of a Replicative DNA Polymerase of the B Family," J. Biol. Chem. 282 (2), 1432-1444 (2007). DOI: 10.1074/jbc.M605675200 Cited 61 times

Eduard Bitto, Craig A. Bingman, Gary E. Wesenberg, Jason G. McCoy, George N. Phillips, Jr., "Structure of aspartoacylase, the brain enzyme impaired in Canavan disease," Proc. Natl. Acad. Sci. USA 104 (2), 456-461 (2007). DOI: 10.1073/pnas.0607817104 Cited 52 times

Koki Makabe, Valentina Tereshko, Grzegorz Gawlak, Shude Yan, Shohei Koide, "Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering," Protein Sci. 15, 1907-1914 (2006). DOI: 10.1110/ps.062246706 Cited 34 times

Y. Xiang, M.C. Morais, A.J. Battisti, S. Grimes, P.J. Jardine, D.L. Anderson, M.G. Rossmann, "Structural changes of bacteriophage [phi]29 upon DNA packaging and release," EMBO J. 25, 5229-5239 (2006). DOI: 10.1038/sj.emboj.7601386 Cited 97 times

Catherine Vilchèze, Feng Wang, Masayoshi Arai, Manzour Hernando Hazbón, Roberto Colangeli, Laurent Kremer, Torin R. Weisbrod, David Alland, James C. Sacchettini, William R . Jacobs, Jr, "Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid," Nat. Med. 12, 1027-1029 (2006). DOI: 10.1038/nm1466 Cited 243 times

Cory J. Gerdts, Valentina Tereshko, Maneesh K. Yadav, Irina Dementieva, Frank Collart, Andrzej Joachimiak, Raymond C. Stevens, Peter Kuhn, Anthony Kossiakoff, Rustem F. Ismagilov, "Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization," Angew. Chem. Int. Ed. 45 (48), 8156-8160 (2006). DOI: 10.1002/anie.200602946 Cited 108 times

Quansheng Liu, Jaclyn C. Greimann, Christopher D. Lima, "Reconstitution, Activities, and Structure of the Eukaryotic RNA Exosome," Cell 127 (6), 1223-1237 (2006). DOI: 10.1016/j.cell.2006.10.037 Cited 412 times

Liang Li, Debarshi Mustafi, Qiang Fu, Valentina Tereshko, Delai L. Chen, Joshua D. Tice, Rustem F. Ismagilov, "Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins," Proc. Natl. Acad. Sci. USA 103 (51), 19243-19248 (2006). DOI: 10.1073/pnas.0607502103 Cited 97 times

Lu Gan, Jeffrey A. Speir, James F. Conway, Gabriel Lander, Naiqian Cheng, Brian A. Firek, Roger W. Hendrix, Robert L. Duda, Lars Liljas, John E. Johnson, "Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM," Structure 14 (11), 1655-1665 (2006). DOI: 10.1016/j.str.2006.09.006 Cited 58 times

Koki Makabe, Dan McElheny, Valentia Tereshko, Aaron Hilyard, Grzegorz Gawlak, Shude Yan, Akiko Koide, Shohei Koide, "Atomic structures of peptide self-assembly mimics," Proc. Natl. Acad. Sci. USA 103 (47), 17753-17758 (2006). DOI: 10.1073/pnas.0606690103 Cited 49 times

Peng R. Chen, Taeok Bae, Wade A. Williams, Erica M. Duguid, Phoebe A. Rice, Olaf Schneewind, Chuan He, "An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus," Nat. Chem. Biol. 2 (11), 591-595 (2006). DOI: 10.1038/nchembio820 Cited 160 times

Susan J. Gagnon, Oleg Y. Borbulevych, Rebecca L. Davis-Harrison, Richard V. Turner, Marale Damirjian, Alison Wojnarowicz, William E. Biddison, Brian M. Baker, "T Cell Receptor Recognition via Cooperative Conformational Plasticity," J. Mol. Biol. 363 (1), 228-243 (2006). DOI: 10.1016/j.jmb.2006.08.045 Cited 61 times

S.G. Podorov, N.N. Faleev, K.M. Pavlov, D.M. Paganin, S.A. Stepanov, E. Förster, "A new approach to wide-angle dynamical X-ray diffraction by deformed crystals," J. Appl. Crystallogr. 39 (5), 652-655 (2006). DOI: 10.1107/S0021889806025696 Cited 16 times

John W. Giraldes, David L. Akey, Jeffrey D. Kittendorf, David H. Sherman, Janet L. Smith, Robert A. Fecik, "Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels," Nat. Chem. Biol. 2 (10), 531-536 (2006). DOI: 10.1038/nchembio822 Cited 73 times

Ling Qin, Carrie Hiser, Anne Mulichak, R. Michael Garavito, Shelagh Ferguson-Miller, "Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase," Proc. Natl. Acad. Sci. USA 103 (44), 16117-16122 (2006). DOI: 10.1073/pnas.0606149103 Cited 247 times

David L. Akey, Jeffrey D. Kittendorf, John W. Giraldes, Robert A. Fecik, David H. Sherman, Janet L. Smith, "Structural basis for macrolactonization by the pikromycin thioesterase," Nat. Chem. Biol. 2 (10), 537-542 (2006). DOI: 10.1038/nchembio824 Cited 97 times

Yong Chen, Yuting Yang, Feng Wang, Ke Wan, Kenichi Yamane, Yi Zhang, Ming Lei, "Crystal structure of human histone lysine-specific demethylase 1 (LSD1)," Proc. Natl. Acad. Sci. USA 103 (38), 13956-13961 (2006). DOI: 10.1073/pnas.0606381103 Cited 205 times

Jill E. Chrencik, Alexei Brooun, Michelle L. Kraus, Michael I. Recht, Anand R. Kolatkar, Gye Won Han, Jan Marcus Seifert, Hans Widmer, Manfred Auer, Peter Kuhn, "Structural and Biophysical Characterization of the EphB4·EphrinB2 Protein-Protein Interaction and Receptor Specificity," J. Biol. Chem. 281 (38), 28185-28192 (2006). DOI: 10.1074/jbc.M605766200 Cited 75 times

J.G. McCoy, C.A. Bingman, E. Bitto, M.M. Holdorf, C.A. Makaroff, G. N. Phillips Jr., "Structure of an ETHE1-like protein from Arabidopsis thaliana," Acta Crystallogr. D 62 (9), 964-970 (2006). DOI: 10.1107/S0907444906020592 Cited 36 times

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Alexei Brooun, Mark Griffith, Kin Moy, Maneesh K. Yadav, Jeffrey Velasquez, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs," J. Virol. 80 (16), 7894-7901 (2006). DOI: 10.1128/JVI.00467-06 Cited 88 times

Kevin G. Hoff, Jose L. Avalos, Kristin Sens, Cynthia Wolberger, "Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD[superscript +] and Acetylated Peptide," Structure 14 (8), 1231-1240 (2006). DOI: 10.1016/j.str.2006.06.006 Cited 113 times

Matthew H. Sazinsky, Sorabh Agarwal, Jose M. Arguello, Amy C. Rosenzweig, "Structure of the actuator domain from the Archaeoglobus fulgidus Cu[superscript +]-ATPase," Biochemistry-US 45 (33), 9949-9955 (2006). DOI: 10.1021/bi0610045 Cited 54 times

Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis, Dinshaw J. Patel, "Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF," Nature 442, 91-95 (2006). DOI: 10.1038/nature04802 Cited 595 times

Tao Wang, Xiangbin Zhang, Poonam Bheda, Javier R. Revollo, Shin-ichiro Imai, Cynthia Wolberger, "Structure of Nampt/PBEF/visfatin, a mammalian NAD[superscript +]biosynthetic enzyme," Nat. Struct. Mol. Biol. 13 (7), 661-662 (2006). DOI: 10.1038/nsmb1114 Cited 211 times

Kiira Ratia, Kumar Singh Saikatendu, Bernard D. Santarsiero, Naina Barretto, Susan C. Baker, Raymond C. Stevens, Andrew D. Mesecar, "Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme," Proc. Natl. Acad. Sci. USA 103 (15), 5717-5722 (2006). DOI: 10.1073/pnas.0510851103 Cited 304 times

Chittaranjan Das, Quyen Q. Hoang, Cheryl A. Kreinbring, Sarah J. Luchansky, Robin K. Meray, Soumya S. Ray, Peter T. Lansbury, Dagmar Ringe, Gregory A. Petsko, "Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1," Proc. Natl. Acad. Sci. USA 103 (12), 4675-4680 (2006). DOI: 10.1073/pnas.0510403103 Cited 156 times

Jason G. McCoy, Lucas J. Bailey, Eduard Bitto, Craig A. Bingman, David J. Aceti, Brian G. Fox, George N. Phillips Jr., "Structure and mechanism of mouse cysteine dioxygenase," Proc. Natl. Acad. Sci. USA 103 (9), 3084-3089 (2006). DOI: 10.1073/pnas.0509262103 Cited 150 times

I.H. Solomon, J.M. Hager, R. Safi, D.P. McDonnell, M.R. Redinbo, E.A. Ortlund, "Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity," J. Mol. Biol. 354 (5), 1091-1102 (2005). Cited 41 times

Eduard Bitto, Craig A. Bingman, Jason G. McCoy, Simon T.M. Allard, Gary E. Wesenberg, George N. Phillips Jr., "The structure at 1.6 Å resolution of the protein product of the At4g34215 gene from Arabidopsis thaliana," Acta Crystallogr. D 61 (12), 1655-1661 (2005). DOI: 10.1107/S0907444905034074 Cited 14 times

Maneesh K. Yadav, Cory J. Gerdts, Ruslan Sanishvili, Ward W. Smith, L. Spencer Roach, Rustem F. Ismagilov, Peter Kuhn, Raymond C. Stevens, "In situ data collection and structure refinement from microcapillary protein crystallization," J. Appl. Crystallogr. 38 (6), 900-905 (2005). Cited 26 times

Kumar Singh Saikatendu, Jeremiah S. Joseph, Vanitha Subramanian, Tom Clayton, Mark Griffith, Kin Moy, Jeffrey Velasquez, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1´´-Phosphate Dephosphorylation by a Conserved Domain of nsP3," Structure 13, 1665-1675 (2005). DOI: 10.1016/j.str.2005.07.022 Cited 145 times

L. Gan, "Best Poster Award, Molecular Biology/Molecular & Experimental Medicine, Society of Fellows 2005 Fall Poster Symposium," (2005).

Jinhua Wu, Aloke K. Bera, Richard J. Kuhn, Janet L. Smith, "Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing," J. Virol. 79 (16), 10268-10277 (2005). DOI: 10.1128/JVI.79.16.10268-10277.2005 Cited 127 times

J.W. Arndt, W. Yu, F. Bi, R.C. Stevens, "Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition," Biochemistry-US 44 (28), 9574-9580 (2005). DOI: 10.1021/bi0505924 Cited 52 times

Simon T.M. Allard, Craig A. Bingman, Kenneth A. Johnson, Gary E. Wesenberg, Eduard Bitto, WonBae Jeon, George N. Phillips Jr., "Structure at 1.6 Å resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana," Acta Crystallogr. F 61 (7), 647-650 (2005). DOI: 10.1107/S1744309105019743 Cited 10 times

Maneesh K. Yadav, James E. Redman, Luke J. Leman, Julietta M. Alvarez-Gutierrez, Yanming Zhang, C. David Stout, M. Reza Ghadiri, "Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides," Biochemistry-US 44 (28), 9723-9732 (2005). DOI: 10.1021/bi050742a Cited 36 times

S. Xu, R.F. Fischetti, "A Ray-Tracing Study of the Dependence of Focal Properties on Surface Figure Error for a Kirkpatrick-Baez (K-B) Mirror System," American Institute of Physics, 705, AIP (2004), 776 - 779.

Sergey Stepanov, "How to make X-ray simulation software working on WWW: A simple recipe based on seven years of experience," Advances in Computational Methods for X-Ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 165 - 170.

S. Stepanov, "X-ray server: an online resource for simulations of X-ray diffraction and scattering," Advances in Computational Methods for X-ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 16 - 26.

J.T. Collins, C.L. Doose, J.N. Attig, M.M. Baehl, "Canted-undulator front-end exit-mask flow-induced vibration measurements," LS-306, (November -2004).

Julia E. Page, Meredith A. Skiba, Truc Do, Andrew C. Kruse, Suzanne Walker, "Metal cofactor stabilization by a partner protein is a widespreadstrategy employed for amidase activation," Proc. Natl. Acad. Sci. USA 119 (26), e2201141119 (2002). DOI: 10.1073/pnas.2201141119

Jennifer Timm, Klajdi Kosovrasti, Mina Henes, Florian Leidner, Shurong Hou, Akbar Ali, Nese Kurt Yilmaz, Celia A. Schiffer, "Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir," ACS Chem. Biol. 15 (2), 342-352 (2000). DOI: 10.1021/acschembio.9b00675


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