Argonne National Laboratory

GM/CA @ APS

Argonne National Laboratory
9700 South Cass Avenue, Bldg 436D

» an Office of Science User Facility

Department of Energy Office of Science
GM/CA @ APS Sponsors:
National Institute of General Medical Sciences (NIGMS) and National Cancer Institute (NCI) of the National Institutes of Health (NIH)
 
GM/CA @ APS users Brian Kobilka and Robert Lefkowitz won the 2012 Nobel Prize in Chemistry.                                                                                                    <a href='news/nobelprize2012.html'>Read more...</a> A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV. Ian Wilson group (Scripps Research Institute) and collaborators                                 <a href='news/2020/IWilson_2020.html'>Read more...</a> Box mini-beam collimator for user-friendly one-click selection of beam size and improved sample visualization.                                                                                 <a href='facilities/minibeam.html'>Read more...</a> Aiming for pan-Lassa virus neutralization. Erica Saphire group (La Jolla Institute for Immunology).                                                                                            <a href='news/2019/ESaphire_2019.html'>Read more...</a> How Fungi Produce Compounds with Potential Pharmaceutical Applications. Janet Smith group (University of Michigan Life Sciences Institute) and collaborators.                                  <a href='https://www.aps.anl.gov/APS-Science-Highlight/2019-09-24/how-fungi-produce-compounds-with-potential-pharmaceutical' target='_blank'>Read more...</a> Versatile, fast, high capacity (18 puck) automounter, based on the Berkeley Automounter (BAM), is implemented on both GM/CA ID beamlines.                                                      <a href='facilities/automounter.html'>Read more...</a> Structurally distinct active conformations within a GPCR. Matt Whorton group (Oregon Health & Science University).                                                                             <a href='news/2019/MWhorton_2019.html'>Read more...</a> Activation of metabotropic glutamate receptors. Brian Kobilka and George Skiniotis groups (Stanford University) and collaborators.                                                             <a href='news/2019/BKobilka_2019.html'>Read more...</a> Polygon diffraction rastering with JBluIce.                                                                                                                                                    <a href='computing/jbluice-epics.html'>Read more...</a> Antitumor activity of multispecific frizzled antibodies. Jean-Philippe Julien group (Hospital for Sick Children Research Institute; University of Toronto) and collaborators.                  <a href='news/2019/JJulien_2019.html'>Read more...</a> Topological control of cytokine receptor signaling. Chris Garcia group (Stanford University), David Baker group (University of Washington), and Vijay Sankaran group (Harvard Medical School). <a href='news/2019/KGarcia_2019.html'>Read more...</a> Staff displaying the first diffraction pattern with Pilatus3 6M (January, 2014). GM/CA beamlines are equipped with Dectris Eiger-16M and Pilatus3-6M detectors.                                <a href='facilities/specifications.html'>Read more...</a> Structural basis for adhesion G protein-coupled receptor Gpr126 function. Demet Araç group (University of Chicago) and collaborators.                                                     <a href='news/2020/DArac_2020.html'>Read more...</a> Structurally distinct active conformations within a GPCR. Robert Lefkowitz group (Duke University) and Andrew Kruse group (Harvard Medical School).                                            <a href='news/2020/AKruse_2020_1.html'>Read more...</a> GM/CA Serial crystallography: using Mylar in situ sandwich plates and 3D-printed holders for room temperature and cryogenic data collection of soluble and membrane protein crystals.          <a href='https://www.ncbi.nlm.nih.gov/pubmed/29300389' target='_blank'>Read more...</a>
   

GM/CA @ APS

The National Institute of General Medical Sciences and National Cancer Institute Structural Biology Facility at the Advanced Photon Source operates a national user facility for structural biology with synchrotron beamlines specializing in intense, tunable micro-beams for crystallography.

Urgent user information during APS restricted operations
 
 
 

What's New

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Highlights

Urgent user information during APS restricted operations. read here
GM/CA @ APS provides serial crystallography capabilities.
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The 13th annual CCP4 School is postponed.
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GM/CA @ APS contributed to the 2012 Nobel Prize in Chemistry. read more
NATURE Technology Feature: GM/CA @ APS mini-beam allows matching beam & crystal sizes. read more
GM/CA @ APS starts reverse site visits.
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GM/CA @ APS is an Office of Science User Facility operated for the U.S. Department of Energy by Argonne National Laboratory

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