Argonne National Laboratory

GM/CA @ APS

Users Publications

Department of Energy Office of Science
GM/CA @ APS Sponsors:
National Institute of General Medical Sciences (NIGMS) and National Cancer Institute (NCI) of the National Institutes of Health (NIH)
 

Information below is an extract from the APS publications database

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Sector: 23 GM/CA-XSD
Number of Records: 1913
Hayley L. Knox, Erica K. Sinner, Craig A. Townsend, Amie K. Boal, Squire J. Booker, "Structure of a B[subscript 12]-dependent radical SAM enzyme in carbapenem biosynthesis," Nature 602, 343-348 (2022). DOI: 10.1038/s41586-021-04392-4

Samantha M. Horwitz, Tamra C. Blue, Joseph A. Ambarian, Shotaro Hoshino, Mohammad R. Seyedsayamdost, Katherine M. Davis, "Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines," RSC Chem. Biol. 3 (4), 420-425 (2022). DOI: 10.1039/D1CB00255D

Brandon M. D'Arcy, Jennifer Arrington, Justin Weisman, Steven B. McClellan, Vandana, Zhengrong Yang, Champion Deivanayagam, Jessa Blount, Aishwarya Prakash, "PMS2 variant results in loss of ATPase activity without compromising mismatch repair," Mol. Genet. Genomics 10 (5), e1908-e1908 (2022). DOI: 10.1002/mgg3.1908

Jacqueto Zephyr, Desaboini Nageswara Rao, Sang V. Vo, Mina Henes, Klajdi Kosovrasti, Ashley N. Matthew, Adam K. Hedger, Jennifer Timm, Elise T. Chan, Akbar Ali, Nese Kurt Yilmaz, Celia A. Schiffer, "Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance," J. Mol. Biol. 434 (9), 167503 (2022). DOI: 10.1016/j.jmb.2022.167503

Hongyuan Lu, Daniel J. Diaz, Natalie J. Czarnecki, Congzhi Zhu, Wantae Kim, Raghav Shroff, Daniel J. Acosta, Bradley R. Alexander, Hannah O. Cole, Yan Zhang, Nathaniel A. Lynd, Andrew D. Ellington, Hal S. Alper, "Machine learning-aided engineering of hydrolases for PET depolymerization," Nature 604, 662-667 (2022). DOI: 10.1038/s41586-022-04599-z

Iredia D. Iyamu, Jonah Z. Vilseck, Ravi Yadav, Nicholas Noinaj, Rong Huang, "Exploring Unconventional SAM Analogues To Build Cell-Potent Bisubstrate Inhibitors for Nicotinamide N-Methyltransferase," Angew. Chem. Int. Ed. 61 (16), e202114813 (2022). DOI: 10.1002/anie.202114813

Cindy M. Spruit, Xueyong Zhu, Ilhan Tomris, María Ríos-Carrasco, Alvin X. Han, Frederik Broszeit, Roosmarijn van der Woude, Kim M. Bouwman, Michel M.T. Luu, Keita Matsuno, Yoshihiro Sakoda, Colin A. Russell, Ian A. Wilson, Geert-Jan Boons, Robert P. de Vries, "N-Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses," J. Virol. 96 (5), e02120 (2022). DOI: 10.1128/jvi.02120-21

Nicholas L. Yan, Reji Nair, Alan Chu, Ian A. Wilson, Kristen A. Johnson, Gareth J. Morgan, Jeffery W. Kelly, "Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site," Bioorg. Med. Chem. Lett. 60, 128571 (2022). DOI: 10.1016/j.bmcl.2022.128571

Zheng Fang Yang, Pankaj Panwar, Ciaran R. McFarlane, Wietske E. Tuinte, Marta Campiglio, Filip Van Petegem, "Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations," Proc. Natl. Acad. Sci. USA 119 (10), e2120416119 (2022). DOI: 10.1073/pnas.2120416119

Brooklyn P. Fedoretz-Maxwell, Catherine H. Shin, Gregory A. MacNeil, Liam J. Worrall, Rachel Park, Natalie C.J. Strynadka, Charles J. Walsby, Jeffrey J. Warren, "The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins," Inorg. Chem. 61 (14), 5563-5571 (2022). DOI: 10.1021/acs.inorgchem.2c00030

Gengnan Li, Krishna Patel, Yi Zhang, Jackson K. Pugmire, Yousong Ding, Steven D. Bruner, "Structural and biochemical studies of an iterative ribosomal peptide macrocyclase," Proteins 90 (3), 670-679 (2022). DOI: 10.1002/prot.26264

Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S. MacGill, Elijah Garcia, Jaeson Calla, Mara Parren, Linlin Yang, Wayne Volkmuth, Emily Locke, Jason A. Regules, Sheetij Dutta, Daniel Emerling, Angela M. Early, Daniel E Neafsey, Elizabeth A. Winzeler, C. Richter King, Fidel Zavala, Dennis R. Burton, Ian A. Wilson, Thomas F. Rogers, "A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum," PLoS Patho. 18 (3), e1010409 (2022). DOI: 10.1371/journal.ppat.1010409

Daichao Wu, Ragul Gowathaman, Brian G. Pierce, Roy A. Mariuzza, "T cell receptors employ diverse strategies to target a p53 cancer neoantigen," J. Biol. Chem. 298 (3), 101684 (2022). DOI: 10.1016/j.jbc.2022.101684

Sergey Stepanov, David Kissick, Oleg Makarov, Mark Hilgart, Michael Becker, Nagarajan Venugopalan, Shenglan Xu, Janet L. Smith, Robert F. Fischetti, "Fast automated energy changes at synchrotron radiation beamlines equipped with transfocator or focusing mirrors," J. Synchrotron Rad. 29 (2), 393-399 (2022). DOI: 10.1107/S1600577522001084

Nathaniel R. Braffman, Terry B. Ruskoski, Katherine M. Davis, Nathaniel R. Glasser, Cassidy Johnson, C. Denise Okafor, Amie K. Boal, Emily P. Balskus, "Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis," eLIFE J. 0, e75761 (2022). DOI: 10.7554/eLife.75761

Rezaul Md Karim, Leixiang Yang, Lihong Chen, Melissa J. Bikowitz, Junhao Lu, Dylan Grassie, Zachary P. Shultz, Justin M. Lopchuk, Jiandong Chen, Ernst Schönbrunn, "Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromodomain," J. Med. Chem. 65 (5), 4182-4200 (2022). DOI: 10.1021/acs.jmedchem.1c01999

Chun Hu, Carlos A. Leche II, Anatoly Kiyatkin, Zhaolong Yu, Steven E. Stayrook, Kathryn M. Ferguson, Mark A. Lemmon, "Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias," Nature 602, 518-522 (2022). DOI: 10.1038/s41586-021-04393-3

Melissa S. Traver, Sarah E. Bradford, Jose Luis Olmos JR, Zachary J. Wright, Mitchell D. Miller, Weijun Xu, George N. Phillips Jr, Bonnie Bartel, "The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex-Insights Into Ubiquitination at the Peroxisomal Membrane," Front. Cell Dev. Biol., 10, 838923 (2022). DOI: 10.3389/fcell.2022.838923

Thuy-Tien T. Nguyen, Sekar Ramachandran, Matthew J. Hill, Richard A. Cerione, "High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding," J. Biol. Chem. 298 (2), 101564 (2022). DOI: 10.1016/j.jbc.2022.101564

Debajit Dey, Suruchi Singh, Saif Khan, Matthew Martin, Nicholas J. Schnicker, Lokesh Gakhar, Brian G. Pierce, S. Saif Hasan, "An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking," Commun. Biol. 5, 115 (2022). DOI: 10.1038/s42003-022-03063-y

Chul-Jin Lee, Robyn Stix, Mitra S. Rana, Flowreen Shikwana, R. Elliot Murphy, Rodolfo Ghirlando, Jose D. Faraldo-Gomez, Anirban Banerjee, "Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase," Proc. Natl. Acad. Sci. USA 119 (7), e2022050119 (2022). DOI: 10.1073/pnas.2022050119

Kinlin L. Chao, Xiaoran Shang, Julia Greenfield, Sara B. Linden, Adit B. Alreja, Daniel C. Nelson, Osnat Herzberg, "Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)," Sci. Rep. 12, 2061 (2022). DOI: 10.1038/s41598-022-06073-2

Nami Tajima, Noriko Simorowski, Remy A. Yovanno, Michael C. Regan, Kevin Michalski, Ricardo Gómez, Albert Y. Lau, Hiro Furukawa, "Development and characterization of functional antibodies targeting NMDA receptors," Nat. Commun. 13, 923 (2022). DOI: 10.1038/s41467-022-28559-3

Abigael J. Kosgei, Mitchell D. Miller, Minakshi Bhardwaj, Weijun Xu, Jon S. Thorson, Steven G. Van Lanen, George N. Phillips Jr, "The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina," Acta Crystallogr. F 78 (1), 1-7 (2022). DOI: 10.1107/S2053230X21012322

Daichao Wu, Alexander Kolesnikov, Rui Yin, Johnathan D. Guest, Ragul Gowthaman, Anton Shmelev, Yana Serdyuk, Dmitry V. Dianov, Grigory A. Efimov, Brian G. Pierce, Roy A. Mariuzza, "Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors," Nat. Commun. 13, 19 (2022). DOI: 10.1038/s41467-021-27669-8

Julie M. Grondin, Guillaume Déjean, Filip Van Petegem, Harry Brumer, "Cell Surface Xyloglucan Recognition and Hydrolysis by the Human Gut Commensal Bacteroides uniformis," Appl. Environ. Microb. 88 (1), e01566 (2022). DOI: 10.1128/AEM.01566-21

Min Qiang, Peixiang Ma, Yu Li, Hejun Liu, Adam Harding, Chenyu Min, Fulian Wang, Lili Liu, Meng Yuan, Qun Ji, Pingdong Tao, Xiaojie Shi, Zhean Li, Teng Li, Xian Wang, Yu Zhang, Nicholas C. Wu, Chang-Chun D. Lee, Xueyong Zhu, Javier Gilbert-Jaramillo, Chuyue Zhang, Abhishek Saxena, Xingxu Huang, Hou Wang, William James, Raymond A. Dwek, Ian A. Wilson, Guang Yang, Richard A. Lerner, "Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago," Adv. Sci. 9 (1), 2102181 (2022). DOI: 10.1002/advs.202102181 Cited 1 times

Samantha Ottavi, Sarah M. Scarry, John Mosior, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, Laurent Goullieux, Christine Roubert, Eric Bacqué, H. Rachel Lagiakos, Jeremie Vendome, Francesca Moraca, Kelin Li, Andrew J. Perkowski, Remya Ramesh, Matthew M. Bowler, William Tracy, Victoria A. Feher, James C. Sacchettini, Ben S. Gold, Carl F. Nathan, Jeffrey Aubé, "In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas," J. Med. Chem. 65 (3), 1996-2022 (2022). DOI: 10.1021/acs.jmedchem.1c01565

Anushweta Asthana, Parameshwaran Ramanan, Alexander Hirschi, Keelan Z. Guiley, Tilini U. Wijeratne, Robert Shelansky, Michael J. Doody, Haritha Narasimhan, Hinrich Boeger, Sarvind Tripathi, Gerd A. Müller, Seth M. Rubin, "The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes," Nat. Commun. 13, 526 (2022). DOI: 10.1038/s41467-022-28094-1

Jianan Zhang, Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, Katherine Chacon-Vargas, Vladimir Yeliseyev, Julie Parsonnet, Thomas D. Haggerty, Guangqiang Wang, Joshua B. Simpson, Parth B. Jariwala, Violet V. Beaty, Jun Yang, Haixia Yang, Anand Panigrahy, Lisa M. Minter, Daeyoung Kim, John G. Gibbons, LinShu Liu, Zhengze Li, Hang Xiao, Valentina Borlandelli, Hermen S. Overkleeft, Erica W. Cloer, Michael B. Major, Dennis Goldfarb, Zongwei Cai, Matthew R. Redinbo, Guodong Zhang, "Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract," Nat. Commun. 13, 136 (2022). DOI: 10.1038/s41467-021-27762-y

Lena Ricemeyer, Nayeli Aguilar-Hernández, Tomás López, Rafaela Espinosa, Sarah Lanning, Santanu Mukherjee, Carolina Cuellar, Susana López, Carlos F. Arias, Rebecca M. DuBois, "Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells," J. Virol. 96 (1), e01415 (2022). DOI: 10.1128/JVI.01415-21

Erich J. Goebel, Chandramohan Kattamuri, Gregory R. Gipson, Lavanya Krishnan, Moises Chavez, Magdalena Czepnik, Michelle C. Maguire, Rosa Grenha, Maria Håkansson, Derek T. Logan, Asya V. Grinberg, Dianne Sako, Roselyne Castonguay, Ravindra Kumar, Thomas B. Thompson, "Structures of activin ligand traps using natural sets of type I and type II TGF[beta] receptors," iScience 25 (21), 103590 (2022). DOI: 10.1016/j.isci.2021.103590

Iga Kucharska, Lamia Hossain, Danton Ivanochko, Qiren Yang, John L Rubinstein, Régis Pomès, Jean-Philippe Julien, "Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats," eLIFE J. 11, e72908 (2022). DOI: 10.7554/eLife.72908

Harsha Gouda, Romila Mascarenhas, Shubhadra Pillay, Markus Ruetz, Markos Koutmos, Ruma Banerjee, "Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions," J. Biol. Chem. 297 (6), 101373 (2021). DOI: 10.1016/j.jbc.2021.101373

Lambros J. Tassoulas, Mikael H. Elias, Lawrence P. Wackett, "Discovery of an ultraspecific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway," J. Biol. Chem. 296, 100055 (2021). DOI: 10.1074/jbc.RA120.015631 Cited 1 times

Samantha Palethorpe, Morgan E. Milton, Everett C. Pesci, John Cavanagh, "Structure of the Acinetobacter baumannii PmrA receiver domain and insights into clinical mutants affecting DNA binding and promoting colistin resistance," J. Biochem. 170 (6), 787-800 (2021). DOI: 10.1093/jb/mvab102

Oluwarotimi Omorodion, Ian A. Wilson, "Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1," J. Mol. Biol. 433 (24), 167303 (2021). DOI: 10.1016/j.jmb.2021.167303

Sharanbasappa S. Karade, Michelle L. Hill, J.L. Kiappes, Rajkumar Manne, Balakishan Aakula, Nicole Zitzmann, Kelly L. Warfield, Anthony M. Treston, Roy A. Mariuzza, "N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum [alpha]-Glucosidases I and II with Antiviral Activity," J. Med. Chem. 64 (24), 18010-18024 (2021). DOI: 10.1021/acs.jmedchem.1c01377

Brittany L. Carroll, Karl E. Zahn, John P. Hanley, Susan S. Wallace, Julie A. Dragon, Sylvie Doublié, "Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis," Nucleic Acids Res. 49 (22), 13165-13178 (2021). DOI: 10.1093/nar/gkab1162

Karen Rosier, Molly T. McDevitt, Joél Smet, Brendan J. Floyd, Maxime Verschoore, Maria J. Marcaida, Craig A. Bingman, Irma Lemmens, Matteo Dal Peraro, Jan Tavernier, Benjamin F. Cravatt, Natalia V. Gounko, Katlijn Vints, Yenthe Monnens, Kritika Bhalla, Laetitia Aerts, Edrees H. Rashan, Arnaud V. Vanlander, Rudy Van Coster, Luc Régal, David J. Pagliarini, John W.M. Creemers, "Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function," iScience 24 (12), 103460 (2021). DOI: 10.1016/j.isci.2021.103460

Juan Feng, Xianchi Dong, Adam DeCosta, Yang Su, Fiona Angrisano, Katarzyna A Sala, Andrew M Blagborough, Chafen Lu, Timothy A Springer, "Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2," eLIFE J. 10, e74707 (2021). DOI: 10.7554/eLife.74707 Cited 1 times

Andriy Kryshtafovych, John Moult, Reinhard Albrecht, Geoffrey A. Chang, Kinlin Chao, Alec Fraser, Julia Greenfield, Marcus D. Hartmann, Osnat Herzberg, Inokentijs Josts, Petr G. Leiman, Sara B. Linden, Andrei N. Lupas, Daniel C. Nelson, Steven D. Rees, Xiaoran Shang, Maria L. Sokolova, Henning Tidow, "Computational models in the service of X-ray and cryo-electron microscopy structure determination," Proteins 89 (12), 1633-1646 (2021). DOI: 10.1002/prot.26223 Cited 8 times

Assaf Alon, Jiankun Lyu, Joao M. Braz, Tia A. Tummino, Veronica Craik, Matthew J. O’Meara, Chase M. Webb, Dmytro S. Radchenko, Yurii S. Moroz, Xi-Ping Huang, Yongfeng Liu, Bryan L. Roth, John J. Irwin, Allan I. Basbaum, Brian K. Shoichet, Andrew C. Kruse, "Structures of the [sigma subscript 2] receptor enable docking for bioactive ligand discovery," Nature 600, 759-764 (2021). DOI: 10.1038/s41586-021-04175-x Cited 5 times

Tao Xiao, Luxin Sun, Min Zhang, Zilu Li, Eric B Haura, Ernst Schonbrunn, Haitao Ji, "Synthesis and structural characterization of a monocarboxylic inhibitor for GRB2 SH2 domain," Bioorg. Med. Chem. Lett. 51, 128354 (2021). DOI: 10.1016/j.bmcl.2021.128354

Ian Miller, Max Totrov, Lioubov Korotchkina, Denis N. Kazyulkin, Andrei V. Gudkov, Sergey Korolev, "Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease," Nucleic Acids Res. 49 (19), 11359-11366 (2021). DOI: 10.1093/nar/gkab826

Tongqing Li, Steven E. Stayrook, Yuko Tsutsui, Jianan Zhang, Yueyue Wang, Hengyi Li, Andrew Proffitt, Stefan G. Krimmer, Mansoor Ahmed, Olivia Belliveau, Ian X. Walker, Krishna C. Mudumbi, Yoshihisa Suzuki, Irit Lax, Diego Alvarado, Mark A. Lemmon, Joseph Schlessinger, Daryl E. Klein, "Structural basis for ligand reception by anaplastic lymphoma kinase," Nature 600, 148-152 (2021). DOI: 10.1038/s41586-021-04141-7 Cited 1 times

Ravi Yadav, Srinivas Govindan, Courtney Daczkowski, Andrew Mesecar, Srinivas Chakravarthy, Nicholas Noinaj, "Structural insight into the dual function of LbpB in mediating Neisserial pathogenesis," eLIFE J. 10, e71683 (2021). DOI: 10.7554/eLife.71683

Ravikumar Reddi, Kimberly Matulef, Erika Riederer, Pierre Moenne-Loccoz, Francis I. Valiyaveetil, "Structures of Gating Intermediates in a K[superscript +] channell," J. Mol. Biol. 433 (13), 167296 (2021). DOI: 10.1016/j.jmb.2021.167296

Shirin Strohmeier, Fatima Amanat, Xueyong Zhu, Meagan McMahon, Meagan E. Deming, Marcela F. Pasetti, Kathleen M. Neuzil, Ian A. Wilson, Florian Kramme, "A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model," mBio 12 (6), e02241 (2021). DOI: 10.1128/mBio.02241-21 Cited 1 times

Jonathan A. Clinger, Yinan Zhang, Yang Liu, Mitchell D. Miller, Ronnie E. Hall, Steven G. Van Lanen, George N. Phillips Jr., Jon S. Thorson, Sherif I. Elshahawi, "Structure and Function of a Dual Reductase–Dehydratase Enzyme System Involved in p-Terphenyl Biosynthesis," ACS Chem. Biol. 16 (12), 2816-2824 (2021). DOI: 10.1021/acschembio.1c00701 Cited 3 times

Nivea Pereira de Sa, Adam Taouil, Jinwoo Kim, Timothy Clement, Reece M. Hoffmann, John E. Burke, Robert C. Rizzo, Iwao Ojima, Maurizio Del Poeta, Michael V. Airola, "Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents," Nat. Commun. 12, 5885 (2021). DOI: 10.1038/s41467-021-26163-5

Qiang Li, Rémi Zallot, Brian S. MacTavish, Alvaro Montoya, Daniel J. Payan, You Hu, John A. Gerlt, Alexander Angerhofer, Valérie de Crécy-Lagard, Steven D. Bruner, "Epoxyqueuosine Reductase QueH in the Biosynthetic Pathway to tRNA Queuosine Is a Unique Metalloenzyme," Biochemistry-US 60 (42), 3152-3161 (2021). DOI: 10.1021/acs.biochem.1c00164

Constantin Giurgiu, Ziyuan Fang, Harry R.M. Aitken, Seohyun Chris Kim, Lydia Pazienza, Shriyaa Mittal, Jack W. Szostak, "Structure–Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis," Angew. Chem. Int. Ed. 60 (42), 22925-22932 (2021). DOI: 10.1002/anie.202109714 Cited 1 times

Rezaul Md Karim, Melissa J. Bikowitz, Alice Chan, Jin-Yi Zhu, Dylan Grassie, Andreas Becker, Norbert Berndt, Steven Gunawan, Nicholas J. Lawrence, Ernst Schönbrunn, "Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors," J. Med. Chem. 64 (21), 15772-15786 (2021). DOI: 10.1021/acs.jmedchem.1c01096 Cited 2 times

Archana G. Chavan, Jeffrey A. Swan†, Joel Heisler, Cigdem Sancar, Dustin C. Ernst, Mingxu Fang, Joseph G. Palacios, Rebecca K. Spangler, Clive R. Bagshaw, Sarvind Tripathi, Priya Crosby, Susan S. Golden, Carrie L. Partch, Andy LiWang, "Reconstitution of an intact clock reveals mechanisms of circadian timekeeping," Science 374 (6564), eabd4453 (2021). DOI: 10.1126/science.abd4453 Cited 4 times

Jaya Joshi, Qiang Li, Jorge D. García-García, Bryan J. Leong, You Hu, Steven D. Bruner, Andrew D. Hanson, "Structure and function of aerotolerant, multiple-turnover THI4 thiazole synthases," Biochem. J. 478 (17), 3265-3279 (2021). DOI: 10.1042/BCJ20210565 Cited 1 times

Olga A. Esakova, Tyler L. Grove, Neela H. Yennawar, Arthur J. Arcinas, Bo Wang, Carsten Krebs, Steven C. Almo, Squire J. Booker, "Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB," Nature 597, 566-570 (2021). DOI: 10.1038/s41586-021-03904-6 Cited 4 times

Fredarla S. Miller, Kathryn K. Crone, Matthew R. Jensen, Sudipta Shaw, William R. Harcombe, Mikael H. Elias, Michael F. Freeman, "Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis," Nat. Commun. 12, 5355 (2021). DOI: 10.1038/s41467-021-25575-7 Cited 1 times

Carolina Alves Feliciano, Brian E. Eckenroth, Oscar R. Diaz, Sylvie Doublie, Aimee Shen, "A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation," PLoS Genet. 17 (9), e1009791 (2021). DOI: 10.1371/journal. pgen.1009791

Nirupa Nagaratnam, Silvia L. Delker, Rebecca Jernigan, Thomas E. Edwards, Janey Snider, Darren Thifault, Dewight Williams, Brent L. Nannenga, Mary Stofega, Lidia Sambucetti, James J. Hsieh, Andrew J. Flint, Petra Fromme, Jose M. Martin-Garcia, "Structural insights into the function of the catalytically active human Taspase1," Structure 29 (8), 873-885 (2021). DOI: 10.1016/j.str.2021.03.008 Cited 1 times

Katsutoshi Sato, Amol A. Padgaonkar, Stacey J. Baker, Stephen C. Cosenza, Olga Rechkoblit, D.R.C. Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R. Port, Aneel K. Aggarwal, M.V. Ramana Reddy, Hanna Y. Irie, E. Premkumar Reddy, "Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease," Nat. Commun. 12, 4671 (2021). DOI: 10.1038/s41467-021-24878-z Cited 2 times

Tatsuki Koike, Masato Yoshikawa, Haruhi Kamisaki Ando, William Farnaby, Toshiya Nishi, Etsurou Watanabe, Jason Yano, Maki Miyamoto, Shigeru Kondo, Tsuyoshi Ishii, Takanobu Kuroita, "Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H)," J. Med. Chem. 64 (16), 12228-12244 (2021). DOI: 10.1021/acs.jmedchem.1c00864 Cited 2 times

Weijing Gu, Shujuan Gao, Huan Wang, Kaelin D. Fleming, Reece M. Hoffmann, Jong Won Yang, Nimi M. Patel, Yong Mi Choi, John E. Burke, Karen Reue, Michael V. Airola, "The middle lipin domain adopts a membrane-binding dimeric protein fold," Nat. Commun. 12, 4718 (2021). DOI: 10.1038/s41467-021-24929-5 Cited 3 times

Meng Yuan, Deli Huang, Chang-Chun D. Lee, Nicholas C. Wu, Abigail M. Jackson, Xueyong Zhu, Hejun Liu, Linghang Peng, Marit J. van Gils, Rogier W. Sanders, Dennis R. Burton, S. Momsen Reincke, Harald Prüss, Jakob Kreye, David Nemazee, Andrew B. Ward, Ian A. Wilson, "Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants," Science 373, 818-823 (2021). DOI: 10.1126/science.abh1139 Cited 60 times

Swetha Raman, Samantha N. Buongervino, Maria V. Lane, Doncho V. Zhelev, Zhongyu Zhu, Hong Cui Cui, Benjamin Martinez, Daniel Martinez, Yanping Wang, Kristen Upton, Khushbu Patel, Komal S. Rathi, Carmen T. Navia, Daniel B. Harmon, Yimei Li, Bruce Pawel, Dimiter S. Dimitrov, John M. Maris, Jean-Philippe Julien, Kristopher R. Bosse, "A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope," Cell Reports 2 (7), 100344 (2021). DOI: 10.1016/j.xcrm.2021.100344 Cited 4 times

Jerry Joe E.K. Harrison, Steve Tuske, Kalyan Das, Francesc X. Ruiz, Joseph D. Bauman, Paul L. Boyer, Jeffrey J. DeStefano, Stephen H. Hughes, Eddy Arnold, "Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)," Viruses-Basel 13 (8), 1495 (2021). DOI: 10.3390/v13081495

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Sean A. Newmister, Kinshuk Raj Srivastava, Rosa V. Espinoza, Kersti Caddell Haatveit, Yogan Khatri, Rachel M. Martini, Marc Garcia-Borràs, Larissa M. Podust, K.N. Houk, David.H. Sherman, "Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway," ACS Catal. 10 (22), 13445-13454 (2020). DOI: 10.1021/acscatal.0c03248 Cited 5 times

Yufei Xiang, Sham Nambulli, Zhengyun Xiao, Heng Liu, Zhe Sang, W. Paul Duprex, Dina Schneidman-Duhovny, Cheng Zhang, Yi Shi, "Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2," Science 370, eabe4747 (2020). DOI: 10.1126/science.abe4747 Cited 66 times

Iga Kucharska, Elaine Thai, Ananya Srivastava, John L. Rubinstein, Régis Pomès, Jean-Philippe Julien, "Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11," eLIFE J. 9, e59018 (2020). DOI: 10.7554/eLife.59018 Cited 2 times

Edurne Rujas, Hong Cui, Taylor Sicard, Anthony Semesi, Jean-Philippe Julien, "Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies," Nat. Commun. 11, 5066 (2020). DOI: 10.1038/s41467-020-18828-4 Cited 6 times

Ahmed Rohaim, Gong LiDong, Li Jing, Rui Huan, Lydia Blachowicz, Benoît Roux, "Barium blockade of the KcsA channel in open and closed conformation datasets," Data in Brief 32, 106135 (2020). DOI: 10.1016/j.dib.2020.106135

Claudio Zambaldo, Minseob Koh, Fariborz Nasertorabi, Gye Won Han, Abhishek Chatterjee, Raymond C. Stevens, Peter G. Schultz, "An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli," Bioorgan. Med. Chem. 28 (20), 115662 (2020). DOI: 10.1016/j.bmc.2020.115662 Cited 2 times

Jinuk Kim, Wonhee Han, Taeyong Park, Eun Jin Kim, Injin Bang, Hyun Sik Lee, Yejing Jeong, Kyeonghwan Roh, Jeesoo Kim, Jong-Seo Kim, Chanhee Kang, Chaok Seok, Jin-Kwan Han, Hee-Jung Choi, "Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains," Nat. Commun. 11, 5357 (2020). DOI: 10.1038/s41467-020-19155-4 Cited 14 times

Marco Lolicato, Andrew M. Natale, Fayal Abderemane-Ali, David Crottès, Sara Capponi, Ramona Duman, Armin Wagner, John M. Rosenberg, Michael Grabe, Daniel L. Minor Jr., "K[subscript 2P] channel C-type gating involves asymmetric selectivity filter order-disorder transitions," Sci. Advances 6 (44), eabc9174 (2020). DOI: 10.1126/sciadv.abc9174 Cited 15 times

Jessica E. Besaw, Wei-Lin Ou, Takefumi Morizumi, Bryan T. Eger, Juan D. Sanchez Vasquez, Jessica H.Y. Chu, Andrew Harris, Leonid S. Brown, R.J. Dwayne Miller, Oliver P. Ernst, "The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants," J. Biol. Chem. 295 (44), 14793-14804 (2020). DOI: 10.1074/jbc.RA120.014118 Cited 4 times

Rafael Maldonado-Hernándezac, Orestes Quesada, José A. Lasalde-Dominiccia, "Biophysical characterization dataset of native nicotinic acetylcholine receptor in lipid-like detergent complexes," Data in Brief 32, 106230 (2020). DOI: 10.1016/j.dib.2020.106230

Qingpin Xiao, Lei Wang, Shreyas Supekar, Tao Shen, Heng Liu, Fei Ye, Junzhou Huang, Hao Fan, Zhiyi Wei, Cheng Zhang, "Structure of human steroid 5[alpha]-reductase 2 with the anti-androgen drug finasteride," Nat. Commun. 11, 5430 (2020). DOI: 10.1038/s41467-020-19249-z Cited 8 times

Jeremy Guerin, Istvan Botos, Zijian Zhang, Karl Lundquist, James C Gumbart, Susan K Buchanan, "Structural insight into toxin secretion by contact-dependent growth inhibition transporters," eLIFE J. 9, e58100 (2020). DOI: 10.7554/eLife.58100 Cited 4 times

Chengcheng Fan, Douglas C. Rees, "Crystal structure of the Escherichia coli transcription termination factor Rho," Acta Crystallogr. F 76 (9), 398-405 (2020). DOI: 10.1107/S2053230X20010572

Samantha M. Ervin, Joshua B. Simpson, Morgan E. Gibbs, Benjamin C. Creekmore, Lauren Lim, William G. Walton, Raad Z. Gharaibeh, Matthew R. Redinbo, "Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases," Biochemistry-US 59 (40), 3939-3950 (2020). DOI: 10.1021/acs.biochem.0c00711 Cited 6 times

Anil R. Mhashal, Adrian Romero-Rivera, Lisa S. Mydy, Judith R. Cristobal, Andrew M. Gulick, John P. Richard, Shina C.L. Kamerlin, "Modeling the Role of a Flexible Loop and Active Site Side Chains in Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase," ACS Catal. 10 (19), 11253-11267 (2020). DOI: 10.1021/acscatal.0c02757 Cited 5 times

Sonu Kumar, Bin Ju, Benjamin Shapero, Xiaohe Lin, Li Ren, Lei Zhang, Dan Li, Zehua Zhou, Yi Feng, Cindy Sou, Colin J. Mann, Yanling Hao, Anita Sarkar, Jiali Hou, Christian Nunnally, Kunxue Hong, Shuo Wang, Xiangyang Ge, Bin Su, Elise Landais, Devin Sok, Michael B. Zwick, Linling He, Jiang Zhu, Ian A. Wilson, Yiming Shao, "A V[subscript H]1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersit," Sci. Advances 6 (38), eabb1328 (2020). DOI: 10.1126/sciadv.abb1328 Cited 4 times

Xiomaris M. Cotto-Rios, Bogos Agianian, Nadege Gitego, Emmanouil Zacharioudakis, Orsi Giricz, Yang Wu, Yiyu Zou, Amit Verma, Poulikos I. Poulikakos, Evripidis Gavathiotis, "Inhibitors of BRAF dimers using an allosteric site," Nat. Commun. 11, 4370 (2020). DOI: 10.1038/s41467-020-18123-2 Cited 16 times

Jun Liu, Rujin Cheng, Ned Van Eps, Nanxi Wang, Takefumi Morizumi, Wei-Lin Ou, Paul C. Klauser, Sharon Rozosky, Oliver P. Ernst, Lei Wang, "Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents," J. Am. Chem. Soc. 142 (40), 17057-17068 (2020). DOI: 10.1021/jacs.0c06820 Cited 7 times

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Britany Rufenach, Darren Christy, Bernhard E. Flucher, Jennifer M. Bui, Jörg Gsponer, Marta Campiglio, Filip Van Petegem, "Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling," Structure 28 (8), 922-932 (2020). DOI: 10.1016/j.str.2020.05.005 Cited 5 times

Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua Wofford, Inna Krieger, Ashutosh Tripathi, John W. Patrick, Debra M. Eckert, Arthur Laganowsky, James Sacchettini, Paul Lindahl, Vytas A. Bankaitis, "A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins," eLIFE J. 9, e57081 (2020). DOI: 10.7554/eLife.57081 Cited 4 times

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Chun-Liang Chen, Lake N. Paul, James C. Mermoud, Calvin Nicklaus Steussy, Cynthia V. Stauffacher, "Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase," Nat. Commun. 11, 3969 (2020). DOI: 10.1038/s41467-020-17733-0 Cited 6 times

Sarah A.H. Hulgan, Abhishek A. Jalan, I-Che Li, Douglas R. Walker, Mitchell D. Miller, Abigael J. Kosgei, Weijun Xu, George N. Phillips Jr., Jeffrey D. Hartgerink, "Covalent Capture of Collagen Triple Helices Using Lysine–Aspartate and Lysine–Glutamate Pairs," Biomacromolecules 21 (9), 3772-3781 (2020). DOI: 10.1021/acs.biomac.0c00878 Cited 7 times

Hunmin Jung, Seongmin Lee, "Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4," Biochem. J. 477 (15), 2859-2871 (2020). DOI: 10.1042/BCJ20200449 Cited 4 times

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Chengcheng Fan, Jens T. Kaiser, Douglas C. Rees, "A structural framework for unidirectional transport by a bacterial ABC exporter," Proc. Natl. Acad. Sci. USA 117 (32), 19228-19236 (2020). DOI: 10.1073/pnas.2006526117 Cited 8 times

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Ngango Y. Rugema, Elisabeth E. Garland-Kuntz, Monita Sieng, Kaushik Muralidharan, Michelle M. Van Camp, Hannah O’Neill, William Mbongo, Arielle F. Selvia, Andrea T. Marti, Amanda Everly, Emmanda McKenzie, Angeline M. Lyon, "Structure of phospholipase C[epsilon] reveals an integrated RA1 domain and previously unidentified regulatory elements," Commun. Biol. 3, 445 (2020). DOI: 10.1038/s42003-020-01178-8 Cited 4 times

Carmen Schwechheimer, Kassidy Hebert, Sarvind Tripathi, Praveen K. Singh, Kyle A. Floyd, Elise R. Brown, Monique E. Porcella, Jacqueline Osorio, Joseph T.M. Kiblen, Fernando A. Pagliai, Knut Drescher, Seth M. Rubin, Fitnat H. Yildiz, "A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae," PLoS Patho. 16 (8), e1008745 (2020). DOI: 10.1371/journal.ppat.1008745 Cited 5 times

Inna V. Krieger, Vladimir Kuznetsov, Jeng-Yih Chang, Junjie Zhang, Samir H. Moussa, Ryland F. Young, James C. Sacchettini, "The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition," J. Mol. Biol. 432 (16), 4623-4636 (2020). DOI: 10.1016/j.jmb.2020.06.013 Cited 6 times

Christina A. Le, Daniel S. Harvey, Stephen G. Aller, "Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein," IUCrJ 7 (4), 663-672 (2020). DOI: 10.1107/S2052252520005709 Cited 10 times

Shoji Maeda, Jun Xu, Francois Marie N. Kadji, Mary J. Clark, Jiawei Zhao, Naotaka Tsutsumi, Junken Aoki, Roger K. Sunahara, Asuka Inoue, K. Christopher Garcia, Brian K. Kobilka, "Structure and selectivity engineering of the M[subscript 1] muscarinic receptor toxin complex," Science 369, 161-167 (2020). DOI: 10.1126/science.aax2517 Cited 16 times

Yuta Tanaka, Osamu Kurasawa, Akihiro Yokota, Michael G. Klein, Bunnai Saito, Shigemitsu Matsumoto, Masanori Okaniwa, Geza Ambrus-Aikelin, Noriko Uchiyama, Daisuke Morishita, Hiromichi Kimura, Shinichi Imamura, "New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase," ACS Med. Chem. Lett. 11 (8), 1645-1652 (2020). DOI: 10.1021/acsmedchemlett.0c00331 Cited 2 times

Rochelle R. Dotas, Trang T. Nguyen, Charles E. Stewart Jr, Rodolfo Ghirlando, Davit A. Potoyan, Vincenzo Venditti, "Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I," J. Mol. Biol. 432 (16), 4481-4498 (2020). DOI: 10.1016/j.jmb.2020.05.024 Cited 7 times

Zhonghua Liu, Chuanping Wang, Jie Yang, Yinghua Chen, Bowen Zhou, Derek W. Abbott, Tsan Sam Xiao, "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage," Immunity 53 (4), 106-114 (2020). DOI: 10.1016/j.immuni.2020.06.007 Cited 24 times

Ian J. Campbell, Olmos Jose Luis Jr., Weijun Xu, Dimithree Kahanda, Joshua T. Atkinson, Othneil Noble Sparks, Mitchell D. Miller, George N. Phillips Jr., George N. Bennett, Jonathan J. Silberg, "Prochlorococcus phage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases," J. Biol. Chem. 295 (31), 10610-10623 (2020). DOI: 10.1074/jbc.RA120.013501 Cited 3 times

Linah N. Rusere, Gordon J. Lockbaum, Mina Henes, Sook-Kyung Lee, Ean Spielvogel, Desaboini Nageswara Rao, Klajdi Kosovrasti, Ellen A. Nalivaika, Ronald Swanstrom, Nese Kurt Yilmaz, Celia A. Schiffer, Akbar Ali, "Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere," J. Med. Chem. 63 (15), 8296-8313 (2020). DOI: 10.1021/acs.jmedchem.0c00529 Cited 2 times

Jan Hellmann, Matthäus Drabek, Jie Yin, Jakub Gunera, Theresa Pröll, Frank Kraus, Christopher J. Langmead, Harald Hübner, Dorothee Weikert, Peter Kolb, Daniel M. Rosenbaum, Peter Gmeiner, "Structure-based development of a subtype-selective orexin 1 receptor antagonist," Proc. Natl. Acad. Sci. USA 117 (30), 18059-18067 (2020). DOI: 10.1073/pnas.2002704117 Cited 12 times

Tsung-Han Chou, Nami Tajima, Annabel Romero-Hernandez, Hiro Furukawa, "Structural basis of functional transitions in mammalian NMDA receptors," Cell 182 (2), 357-371 (2020). DOI: 10.1016/j.cell.2020.05.052 Cited 20 times

Netanel Tzarum, Erick Giang, Rameshwar U. Kadam, Fang Chen, Kenna Nagy, Elias H. Augestad, Rodrigo Velázquez-Moctezuma, Zhen-Yong Keck, Yuanzi Hua, Robyn L. Stanfield, Marlene Dreux, Jannick Prentoe, Steven K.H. Foung, Jens Bukh, Ian A. Wilson, Mansun Law, "An alternate conformation of HCV E2 neutralizing face as an additional vaccine target," Sci. Advances 6 (30), eabb5642 (2020). DOI: 10.1126/sciadv.abb5642 Cited 11 times

Dongxing Chen, Cheng Dong, Guangping Dong, Karthik Srinivasan, Jinrong Min, Nicholas Noinaj, Rong Huang, "Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues," J. Med. Chem. 63 (15), 8419-8431 (2020). DOI: 10.1021/acs.jmedchem.0c00770 Cited 9 times

Brianna D. Mackie, Dongxing Chen, Guangping Dong, Cheng Dong, Haley Parker, Christine E. Schaner Tooley, Nicholas Noinaj, Jinrong Min, Rong Huang, "Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies," J. Med. Chem. 63 (17), 9512-9522 (2020). DOI: 10.1021/acs.jmedchem.0c00689 Cited 4 times

Sohyoung Lee, Yi-An Yang, Shawn K. Milano, Tri Nguyen, Changhwan Ahn, Ji Hyun Sim, Andrew J. Thompson, Eric C. Hillpot, Gyeongshik Yoo, James C. Paulson, Jeongmin Song, "Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence," Cell Host Microbe 27 (6), 937-949 (2020). DOI: 10.1016/j.chom.2020.04.005 Cited 10 times

Eliza Ruben, William Planer, Mathivanan Chinnaraj, Zhiwei Chen, Xiaobing Zuo, Vittorio Pengo, Vincenzo De Filippis, Ravi K. Alluri, Keith R. McCrae, Paolo Macor, Francesco Tedesco, Nicola Pozzi, "The J-elongated conformation of [beta]2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome," J. Biol. Chem. 295 (31), 10794-10806 (2020). DOI: 10.1074/jbc.RA120.013939 Cited 9 times

Evan M. Alexander, Dale F. Kreitler, Valeria Guidolin, Alexander K. Hurben, Eric Drake, Peter W. Villalta, Silvia Balbo, Andrew M. Gulick, Courtney C. Aldrich, "Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca," ACS Infect. Dis. 6 (7), 1976-1997 (2020). DOI: 10.1021/acsinfecdis.0c00326 Cited 5 times

Wei-Cheng Lu, Achinto Saha, Wupeng Yan, Kendra Garrison, Candice Lamb, Renu Pandey, Seema Irani, Alessia Lodi, Xiyuan Lu, Stefano Tiziani, Yan Jessie Zhang, George Georgiou, John DiGiovanni, Everett Stone, "Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity," Proc. Natl. Acad. Sci. USA 117 (23), 13000-13011 (2020). DOI: 10.1073/pnas.1917362117 Cited 11 times

Daichao Wu, D. Travis Gallagher, Ragul Gowthaman, Brian G. Pierce, Roy A. Mariuzza, "Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen," Nat. Commun. 11, 2908 (2020). DOI: 10.1038/s41467-020-16755-y Cited 12 times

Bryan J. Jones, Robert L. Evans III, Nathan J. Mylrea, Debayan Chaudhury, Christine Luo, Bo Guan, Colin T. Pierce, Wendy R. Gordon, Carrie M. Wilmot, Romas J. Kazlauskas, "Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity," PLoS One 15 (6), e0235341 (2020). DOI: 10.1371/journal.pone.0235341 Cited 5 times

Lee Makowski, "The Structural Basis of Amyloid Strains in Alzheimer’s Disease," ACS Biomater. Sci. Eng. 6 (5), 2498-2505 (2020). DOI: 10.1021/acsbiomaterials.9b01302

Robyn L. Stanfield, Zachary T. Berndsen, Ruiqi Huang, Devin Sok, Gabrielle Warner, Jonathan L. Torres, Dennis R. Burton, Andrew B. Ward, Ian A. Wilson, Vaughn V. Smider, "Structural basis of broad HIV neutralization by a vaccine-induced cow antibody," Sci. Advances 6 (22), eaba0468 (2020). DOI: 10.1126/sciadv.aba0468 Cited 9 times

Rajagopal Murugan, Stephen W. Scally, Giulia Costa, Ghulam Mustafa, Elaine Thai, Tizian Decker, Alexandre Bosch, Katherine Prieto, Elena A. Levashina, Jean-Philippe Julien, Hedda Wardemann, "Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs," Nat. Med. 26, 1135-1145 (2020). DOI: 10.1038/s41591-020-0881-9 Cited 25 times

Hala Ouzon-Shubeita, Hunmin Jung, Michelle H. Lee, Myong-Chul Koag, Seongmin Lee, "Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4," Biochem. J. 477 (9), 1601-1612 (2020). DOI: 10.1042/BCJ20200125 Cited 2 times

Shannon R. Esswein, Harry B. Gristick, Andrea Jurado, Avery Peace, Jennifer R. Keeffe, Yu E. Lee, Alisa V. Voll, Mohsan Saeed, Michel C. Nussenzweig, Charles M. Rice, Davide F. Robbiani, Margaret R. MacDonald, Pamela J. Bjorkman, "Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody," Proc. Natl. Acad. Sci. USA 117 (18), 9865-9875 (2020). DOI: 10.1073/pnas.1919269117 Cited 4 times

Ying Ye, Lei Du, Xingwang Zhang, Sean A. Newmister, Morgan McCauley, Juan V. Alegre-Requena, Wei Zhang, Shuai Mu, Atsushi Minami, Amy E. Fraley, Maria L. Adrover-Castellano, Nolan A. Carney, Vikram V. Shende, Feifei Qi, Hideaki Oikawa, Hikaru Kato, Sachiko Tsukamoto, Robert S. Paton, Robert M. Williams, David H. Sherman, Shengying Li, "Fungal-derived brevianamide assembly by a stereoselective semipinacolase," Nat. Catalysis 3, 497-506 (2020). DOI: 10.1038/s41929-020-0454-9 Cited 19 times

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Brandyn R. West, Crystal L. Moyer, Liam B. King, Marnie L. Fusco, Jacob C. Milligan, Sean Hui, Erica Ollmann Saphire, "Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope," mBio 9 (5), e01674-1-e01674-18 (2018). DOI: 10.1128/mBio.01674-18 Cited 23 times

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Greg Hicks, Zongchao Jia, "Structural Basis for the Lipopolysaccharide Export Activity of the Bacterial Lipopolysaccharide Transport System," Int. J. Mol. Sci. 19 (9), 2680-1-2680-12 (2018). DOI: 10.3390/ijms19092680 Cited 13 times

Gopal P. Dahal, Ronald E. Viola, "Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase," Biochem. Biophys. Res. Commun. 503 (4), 2848-2854 (2018). DOI: 10.1016/j.bbrc.2018.08.053 Cited 6 times

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John D. McCorvy, Daniel Wacker, Sheng Wang, Bemnat Agegnehu, Jing Liu, Katherine Lansu, Alexandra R. Tribo, Reid H.J. Olsen, Tao Che, Jian Jin, Bryan L. Roth, "Structural determinants of 5-HT[subscript 2B] receptor activation and biased agonism," Nat. Struct. Mol. Biol. 25, 787-796 (2018). DOI: 10.1038/s41594-018-0116-7 Cited 47 times

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Brandon R. Goblirsch, Buenafe T. Arachea, Daniel J. Councell, Michael C. Wiener, "Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24," Acta Crystallogr. D 74 (8), 739-747 (2018). DOI: 10.1107/S2059798318003431 Cited 4 times

Ignacio Mir-Sanchis, Ying Zhang Pigli, Phoebe Ann Rice, "Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements," Structure 26 (8), 1144-1150 (2018). DOI: 10.1016/j.str.2018.05.016 Cited 4 times

Benoît Desguin, Matthias Fellner, Olivier Riant, Jian Hu, Robert P. Hausinger, Pascal Hols, Patrice Soumillion, "Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase," J. Biol. Chem. 293 (32), 12303-12317 (2018). DOI: 10.1074/jbc.RA118.003741 Cited 15 times

Daniel J. Falconer, Ganesh P. Subedi, Aaron M. Marcella, Adam W. Barb, "Antibody Fucosylation Lowers the Fc[gamma]RIIIa/CD16a Affinity by Limiting the Conformations Sampled by the N162-Glycan," ACS Chem. Biol. 13 (8), 2179-2189 (2018). DOI: 10.1021/acschembio.8b00342 Cited 37 times

Matteo Bianchi, Hannah L. Turner, Bartek Nogal, Christopher A. Cottrell, David Oyen, Matthias Pauthner, Raiza Bastidas, Rebecca Nedellec, Laura E. McCoy, Ian A. Wilson, Dennis R. Burton, Andrew B. Ward, Lars Hangartner, "Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization," Immunity 49 (2), 288-300 (2018). DOI: 10.1016/j.immuni.2018.07.009 Cited 83 times

Ashootosh Tripathi, Sung Ryeol Park, Andrew P. Sikkema, Hyo Je Cho, Jianfeng Wu, Brian Lee, Chuanwu Xi, Janet L. Smith, David H. Sherman, "A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit–Activating Enzyme CahJ," ChemBioChem 19 (15), 1595-1600 (2018). DOI: 10.1002/cbic.201800233 Cited 7 times

Celine Bergonzi, Michael Schwab, Tanushree Naik, David Daudé, Eric Chabrière, Mikael Elias, "Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties," Sci. Rep. 8, 11262-1-11262-13 (2018). DOI: 10.1038/s41598-018-28988-5 Cited 13 times

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Chao Fan, Minrui Fan, Benjamin J. Orlando, Nathan M. Fastman, Jinru Zhang, Yan Xu, Melissa G. Chambers, Xiaofang Xu, Kay Perry, Maofu Liao, Liang Feng, "X-ray and cryo-EM structures of the mitochondrial calcium uniporter," Nature 559, 575-579 (2018). DOI: 10.1038/s41586-018-0330-9 Cited 77 times

Colin Havenar-Daughton, Anita Sarkar, Daniel W. Kulp, Laura Toy, Xiaozhen Hu, Isaiah Deresa, Oleksandr Kalyuzhniy, Kirti Kaushik, Amit A. Upadhyay, Sergey Menis, Elise Landais, Liwei Cao, Jolene K. Diedrich, Sonu Kumar, Torben Schiffner, Samantha M. Reiss, Grégory Seumois, John R. Yates, James C. Paulson, Steven E. Bosinger, Ian A. Wilson, William R. Schief, Shane Crotty, "The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen," Sci. Transl. Med. 10 (448), eaat0381-1-eaat0381 (2018). DOI: 10.1126/scitranslmed.aat0381 Cited 55 times

Pengxiang Huang, Sanduo Zheng, Bradley M. Wierbowski, Youngchang Kim, Daniel Nedelcu, Laura Aravena, Jing Liu, Andrew C. Kruse, Adrian Salic, "Structural Basis of Smoothened Activation in Hedgehog Signaling," Cell 174 (2), 312-324 (2018). DOI: 10.1016/j.cell.2018.04.029 Cited 74 times

Adam J. Simpkin, Felix Simkovic, Jens M.H. Thomas, Martin Savko, Andrey Lebedev, Ville Uski, Charles Ballard, Marcin Wojdyr, Rui Wu, Ruslan Sanishvili, Yibin Xu, María-Natalia Lisa, Alejandro Buschiazzo, William Shepard, Daniel J. Rigden, Ronan M. Keegan, "SIMBAD: a sequence-independent molecular-replacement pipeline," Acta Crystallogr. D 74 (7), 595-605 (2018). DOI: 10.1107/S2059798318005752 Cited 20 times

Fernando Aleman, Netanel Tzarum, Leopold Kong, Kenna Nagy, Jiang Zhu, Ian A. Wilson, Mansun Law, "Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors," Proc. Natl. Acad. Sci. USA 115 (29), 7569-7574 (2018). DOI: 10.1073/pnas.1802378115 Cited 8 times

Tengchuan Jin, Eric Brefo-Mensah, Weirong Fan, Weihong Zeng, Yajuan Li, Yuzhu Zhang, Michael Palmer, "Crystal structure of the Streptococcus agalactiae CAMP factor provides insights into its membrane-permeabilizing activity," J. Biol. Chem. 293 (30), 11867-11877 (2018). DOI: 10.1074/jbc.RA118.002336 Cited 8 times

Yajuan Li, Yi Huang, Xiaocong Cao, Xueying Yin, Xiangyu Jin, Sheng Liu, Jiansheng Jiang, Wei Jiang, Tsan Sam Xiao, Rongbin Zhou, Gang Cai, Bing Hu, Tengchuan Jin, "Functional and structural characterization of zebrafish ASC," FEBS J. 285 (14), 2691-2707 (2018). DOI: 10.1111/febs.14514 Cited 18 times

Thandeka Moyo, June Ereño-Orbea, Rajesh Abraham Jacob, Clara E. Pavillet, Samuel Mundia Kariuki, Emily N. Tangie, Jean-Philippe Julien, Jeffrey R. Dorfman, "Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11," J. Virol. 92 (14), e02261-1 -e02261-17 (2018). DOI: 10.1128/JVI.02261-17 Cited 10 times

Marianne Goris, Robert S. Magin, Håvard Foyn, Line M. Myklebust, Sylvia Varland, Rasmus Ree, Adrian Drazic, Parminder Bhambra, Svein I. Støve, Markus Baumann, Bengt Erik Haug, Ronen Marmorstein, Thomas Arnesen, "Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80," Proc. Natl. Acad. Sci. USA 115 (17), 4405-4410 (2018). DOI: 10.1073/pnas.1719251115 Cited 33 times

Heng Liu, Hee Ryung Kim, R.N. Deepak, Lei Wang, Ka Young Chung, Hao Fan, Zhiyi Wei, Cheng Zhang, "Orthosteric and allosteric action of the C5a receptor antagonists," Nat. Struct. Mol. Biol. 25, 472-481 (2018). DOI: 10.1038/s41594-018-0067-z Cited 61 times

Lilian González-Segura, Carlos Mújica-Jiménez, Javier Andrés Juárez-Díaz, Rodrigo Güémez-Toro, León P. Martinez-Castilla, Rosario A. Muñoz-Clares, "Identification of the allosteric site for neutral amino acids in the maize C4 isozyme of phosphoenolpyruvate carboxylase: The critical role of Ser-100," J. Biol. Chem. 293 (26), 9945-9957 (2018). DOI: 10.1074/jbc.RA118.002884 Cited 7 times

Alan T. Culbertson, Jacqueline J. Ehrlich, Jun-Yong Choe, Richard B. Honzatko, Olga A. Zabotina, "Structure of xyloglucan xylosyltransferase 1 reveals simple steric rules that define biological patterns of xyloglucan polymers," Proc. Natl. Acad. Sci. USA 115 (23), 6064-6069 (2018). DOI: 10.1073/pnas.1801105115 Cited 21 times

Scott T. Aoki, Douglas F. Porter, Aman Prasad, Marvin Wickens, Craig A. Bingman, Judith Kimble, "An RNA-Binding Multimer Specifies Nematode Sperm Fate," Cell Reports 23 (13), 3769-3775 (2018). DOI: 10.1016/j.celrep.2018.05.095 Cited 6 times

Egor Svidritskiy, Andrei A. Korostelev, "Conformational Control of Translation Termination on the 70S Ribosome," Structure 26 (6), 821-828 (2018). DOI: 10.1016/j.str.2018.04.001 Cited 14 times

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Kimmo Rantalainen, Zachary T. Berndsen, Sasha Murrell, Liwei Cao, Oluwarotimi Omorodion, Jonathan L. Torres, Mengyu Wu, Jeffrey Umotoy, Jeffrey Copps, Pascal Poignard, Elise Landais, James C. Paulson, Ian A. Wilson, Andrew B. Ward, "Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design," Cell Reports 23 (11), 3249-3261 (2018). DOI: 10.1016/j.celrep.2018.05.046 Cited 32 times

Joel A. Rankin, Robert C. Mauban, Matthias Fellner, Benoît Desguin, John McCracken, Jian Hu, Sergey A. Varganov, Robert P. Hausinger, "Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism," Biochemistry-US 57 (23), 3244-3251 (2018). DOI: 10.1021/acs.biochem.8b00100 Cited 13 times

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Sanduo Zheng, Lok-To Sham, Frederick A. Rubino, Kelly P. Brock, William P. Robins, John J. Mekalanos, Debora S. Marks, Thomas G. Bernhardt, Andrew C. Kruse, "Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli," Proc. Natl. Acad. Sci. USA 115 (26), 6709-6714 (2018). DOI: 10.1073/pnas.1802192115 Cited 30 times

Daniel C. Bailey, Evan Alexander, Matthew R. Rice, Eric J. Drake, Lisa S. Mydy, Courtney C. Aldrich, Andrew M. Gulick, "Structural and functional delineation of aerobactin biosynthesis in hypervirulent Klebsiella pneumoniae," J. Biol. Chem. 293 (20), 7841-7852 (2018). DOI: 10.1074/jbc.RA118.002798 Cited 23 times

Seema Irani, Nathchar Naowarojna, Yang Tang, Karan R. Kathuria, Shu Wang, Anxhela Dhembi, Norman Lee, Wupeng Yan, Huijue Lyu, Catherine E. Costello, Pinghua Liu, Yan Jessie Zhang, "Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism," Cell Chem. Biol. 25 (5), 519-529 (2018). DOI: 10.1016/j.chembiol.2018.02.002 Cited 16 times

Hannah R. Rose, Manas K. Ghosh, Ailiena O. Maggiolo, Christopher J. Pollock, Elizabeth J. Blaesi, Viviane Hajj, Yifeng Wei, Lauren J. Rajakovich, Wei-chen Chang, Yilin Han, Mariana Hajj, Carsten Krebs, Alexey Silakov, Maria-Eirini Pandelia, J. Martin Bollinger Jr., Amie K. Boal, "Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor," Biochemistry-US 57 (18), 2679-2693 (2018). DOI: 10.1021/acs.biochem.8b00247 Cited 22 times

Raoul De Gasparo, Elke Brodbeck‐Persch, Steve Bryson, Nina B. Hentzen, Marcel Kaiser, Emil F. Pai, "Biological Evaluation and X‐ray Co‐crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma," ChemMedChem 13 (9), 957-967 (2018). DOI: 10.1002/cmdc.201800067 Cited 10 times

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Michael S. Little, Matthew R. Redinbo, "Crystal structure of the mouse innate immunity factor bacterial permeability-increasing family member A1," Acta Crystallogr. F 74 (5), 268-276 (2018). DOI: 10.1107/S2053230X18004600 Cited 2 times

Daniel C. Bailey, Evan Alexander, Matthew R. Rice, Eric J. Drake, Lisa S Mydy, Courtney C. Aldrich, Andrew M. Gulick, "Structural and Functional Delineation of Aerobactin Biosynthesis in Hypervirulentklebsiella Pneumoniae," J. Biol. Chem. 293 (20), 7841-7852 (2018). DOI: 10.1074/jbc.RA118.002798 Cited 23 times

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Kate L. White, Matthew T. Eddy, Zhan-Guo Gao, Gye Won Han, Tiffany Lian, Alexander Deary, Nilkanth Patel, Kenneth A. Jacobson, Vsevolod Katritch, Raymond C. Stevens, "Structural Connection between Activation Microswitch and Allosteric Sodium Site in Gpcr Signaling," Structure 26 (2), 259-269 (2018). DOI: 10.1016/j.str.2017.12.013 Cited 64 times

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Daniel J. Falconer, Adam W. Barb, "Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1," PLoS One 13 (2), e0192123-1-e0192123-17 (2018). DOI: 10.1371/journal.pone.0192123 Cited 5 times

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Aram Chang, Fayal Abderemane-Ali, Greg L. Hura, Nathan D. Rossen, Rachel E. Gate, Daniel L. Minor Jr., "A Calmodulin C-Lobe Ca[superscript 2+]-Dependent Switch Governs Kv7 Channel Function," Neuron 97 (4), 836-852 (2018). DOI: 10.1016/j.neuron.2018.01.035 Cited 37 times

Benjamin C. Campbell, Gregory A. Petsko, Ce Feng Liu, "Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors," Structure 26 (2), 225-237 (2018). DOI: 10.1016/j.str.2017.12.006 Cited 6 times

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Michael S. Little, Samuel J. Pellock, William G. Walton, Ashutosh Tripathy, Matthew R. Redinbo, "Structural basis for the regulation of [beta]-glucuronidase expression by human gut Enterobacteriaceae," Proc. Natl. Acad. Sci. USA 115 (2), E152-E161 (2018). DOI: 10.1073/pnas.1716241115 Cited 24 times

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Lingfei Liang, Haiyan Zhao, Bowen An, Liang Tang, "High-resolution structure of podovirus tail adaptor suggests repositioning of an octad motif that mediates the sequential tail assembly," Proc. Natl. Acad. Sci. USA 115 (2), 313-318 (2018). DOI: 10.1073/pnas.1706846115 Cited 5 times

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Yao Fang, Xiao Xiao, Shu-Xing Li, Aaron Wolfe, Xiaojiang S. Chen, "Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA," J. Mol. Biol. 430 (1), 87-101 (2018). DOI: 10.1016/j.jmb.2017.11.007 Cited 18 times

Walter A. Bogdanoff, Edmundo I. Perez, Tomás López, Carlos F. Arias, Rebecca M. DuBois, "Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design," J. Virol. 92 (1), e01546-1-e01546-17 (2018). DOI: 10.1128/JVI.01546-17 Cited 10 times

Guennadi Kozlov, Kathy Wong, Wenxuan Wang, Pavol Skubák, Juliana Muñoz-Escobar, Yue Liu, Nadeem Siddiqui, Navraj S. Pannu, Kalle Gehring, "Ankyrin repeats as a dimerization module," Biochem. Biophys. Res. Commun. 495 (1), 1002-1007 (2018). DOI: 10.1016/j.bbrc.2017.11.135 Cited 2 times

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Tengchuan Jin, Mo Huang, Jiansheng Jiang, Patrick Smith, Tsan Sam Xiao, "Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction," PLoS One 13 (1), e0190547-1-e0190547-11 (2018). DOI: https://doi.org/10.1371/journal.pone.0190547

Kazuhiro Yamadaa, Markos Koutmos, "The folate-binding module of Thermus thermophilus cobalamin-dependent methionine synthase displays a distinct variation of the classical TIM barrel: a TIM barrel with a ‘twist’," Acta Crystallogr. D 74 (1), 41-51 (2018). DOI: 10.1107/S2059798317018290

Eric M. Lewandowski, Kathryn G. Lethbridge, Ruslan Sanishvili, Joanna Skiba, Konrad Kowalski, Yu Chen, "Mechanisms of proton relay and product release by Class A [beta]‐lactamase at ultrahigh resolution," FEBS J. 285 (1), 87-100 (2018). DOI: 10.1111/febs.14315 Cited 9 times

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Brian J. McMillan, Brandon Zimmerman, Emily D. Egan, Michael Lofgren, Xiang Xu, Anthony Hesser, Stephen C. Blacklow, "Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations," Glycobiology 27 (8), 777-786 (2017). DOI: 10.1093/glycob/cwx020 Cited 30 times

Alayna M. George Thompson, Cristina V. Iancu, Kenneth E. Neet, John V. Dean, Jun-yong Choe, "Differences in salicylic acid glucose conjugations by UGT74F1 and UGT74F2 from Arabidopsis thaliana," Sci. Rep. 7, 46629-1-46629-11 (2017). DOI: 10.1038/srep46629 Cited 59 times

Ralph Pantophlet, Nino Trattnig, Sasha Murrell, Naiomi Lu, Dennis Chau, Caitlin Rempel, Ian A. Wilson, Paul Kosma, "Bacterially Derived Synthetic Mimetics of Mammalian Oligomannose Prime Antibody Responses That Neutralize Hiv Infectivity," Nat. Commun. 8 (1), 1601-1-1601-12 (2017). DOI: 10.1038/s41467-017-01640-y Cited 17 times

Megan P.D. Zahniser, Shreenath Prasad, Malea M. Kneen, Cheryl A. Kreinbring, Gregory A. Petsko, Dagmar Ringe, Michael J. McLeish, "Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily," Protein Eng. Des. Sel. 30 (3), 271-278 (2017). DOI: https://doi.org/10.1093/protein/gzx015

Ruslan Sanishvili, Robert F. Fischetti, "Applications of X-Ray Micro-Beam for Data Collection," Protein Crystallography: Methods and Protocols, A. Wlodawer, Z. Dauter, M. Jaskolski, eds., Humana Press, 2017, 219 - 238. DOI: 10.1007/978-1-4939-7000-1_9

Xiao Xiao, Hanjing Yang, Vagan Arutiunian, Yao Fang, Guillaume Besse, Cherie Morimoto, Brett Zirkle, Xiaojiang S. Chen, "Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation," Nucleic Acids Res. 45 (12), 7494-7506 (2017). DOI: 10.1093/nar/gkx362 Cited 22 times

Matthew R. Jensen, Brandon R. Goblirsch, James K. Christenson, Morgan A. Esler, Fatuma A. Mohamed, Lawrence P. Wackett, Carrie M. Wilmot, "OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis," Biochem. J. 474 (23), 3871-3886 (2017). DOI: 10.1042/BCJ20170642 Cited 4 times

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Chun-Liang Chen, James C. Mermoud, Lake N. Paul, Calvin Nicklaus Steussy, Cynthia V. Stauffacher, "Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis," J. Biol. Chem. 292 (52), 21340-21351 (2017). DOI: 10.1074/jbc.M117.802223 Cited 6 times

Jayakanth Kankanala, Karen A. Kirby, Andrew D. Huber, Mary C. Casey, Daniel J. Wilson, StefanG. Sarafianos, Zhengqiang Wang, "Design, Synthesis and Biological Evaluations of N-Hydroxy Thienopyrimidine-2,4-Diones as Inhibitors of Hiv Reverse Transcriptase-Associated Rnase H," Eur. J. Med. Chem. 141, 149-161 (2017). DOI: 10.1016/j.ejmech.2017.09.054 Cited 28 times

Jiansheng Jiang, Kannan Natarajan, Lisa F. Boyd, Giora I. Morozov, Michael G. Mage, David H. Margulies, "Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation," Science 358, 1064-1068 (2017). DOI: 10.1126/science.aao5154 Cited 66 times

Bernard C. Collins, Robin J. Gunn, Tanya R. McKitrick, Richard D. Cummings, Max D. Cooper, Brantley R. Herrin, Ian A. Wilson, "Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates," Structure 25 (11), 1667-1678 (2017). DOI: 10.1016/j.str.2017.09.003 Cited 20 times

Aaron M. Marcella, Sannie J. Culbertson, Michael A. Shogren-Knaak, Adam W. Barb, "Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex," J. Mol. Biol. 429 (23), 3763-3775 (2017). DOI: 10.1016/j.jmb.2017.10.015 Cited 12 times

Ryan P. Emptage, Megan J. Schoenberger, Kathryn M. Ferguson, Ronen Marmorstein, "Intramolecular Autoinhibition of Checkpoint Kinase 1 Is Mediated by Conserved Basic Motifs of the C-Terminal Kinase-Associated 1 Domain," J. Biol. Chem. 292 (46), 19024-19033 (2017). DOI: 10.1074/jbc.M117.811265 Cited 10 times

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Azhad U. Chowdhury, Christopher M. Dettmar, Shane Z. Sullivan, Shijie Zhang, Kevin T. Jacobs, David J. Kissick, Thora Maltais, Hartmut G. Hedderich, Patricia A. Bishop, Garth J. Simpson, "Kinetic Trapping of Metastable Amino Acid Polymorphs," J. Am. Chem. Soc. 136 (6), 2404-2412 (2014). DOI: 10.1021/ja410293p Cited 23 times

Gustavo Fenalti, Patrick M. Giguere, Vsevolod Katritch, Xi-Ping Huang, Aaron A. Thompson, Vadim Cherezov, Bryan L. Roth, Raymond C. Stevens , "Molecular control of [delta]-opioid receptor signalling," Nature 506, 191-196 (2014). DOI: 10.1038/nature12944 Cited 328 times

Kurt H. Piepenbrink, Grace A. Maldarelli, Claudia F. Martinez de la Peña, George L. Mulvey, Greg A. Snyder, Leon De Masi, Erik C. von Rosenvinge, Sebastian Günther, Glen D. Armstrong, Michael S. Donnenberg, Eric J. Sundberg, "Structure of Clostridium difficile PilJ Exhibits Unprecedented Divergence from Known Type IV Pilins," J. Biol. Chem. 289 (7), 4334-4345 (2014). DOI: 10.1074/jbc.M113.534404 Cited 26 times

Anoop Narayanan, Shivesh Kumar, Amanda N. Evrard, Lake N. Paul, Dinesh A. Yernool , "An asymmetric heterodomain interface stabilizes a response regulator–DNA complex," Nat. Commun. 5, 3282-1-3282-9 (2014). DOI: 10.1038/ncomms4282 Cited 39 times

Mark A. Blenner, Xianchi Dong, Timothy A. Springer, "Structural Basis of Regulation of von Willebrand Factor Binding to Glycoprotein Ib," J. Biol. Chem. 289 (9), 5565-5579 (2014). DOI: 10.1074/jbc.M113.511220 Cited 45 times

Karen Tran, Christian Poulsen, Javier Guenaga, Natalia de Val, Richard Wilson, Christopher Sundling, Yuxing Li, Robyn L. Stanfield, Ian A. Wilson, Andrew B. Ward, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, "Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign," Proc. Natl. Acad. Sci. USA 111 (7), E738-E747 (2014). DOI: 10.1073/pnas.1319512111 Cited 60 times

Atsushi Yahashiri, Jon K. Rubach, Bryce V. Plapp, "Effects of Cavities at the Nicotinamide Binding Site of Liver Alcohol Dehydrogenase on Structure, Dynamics and Catalysis," Biochemistry-US 53 (5), 881-894 (2014). DOI: 10.1021/bi401583f Cited 12 times

David L. Akey, W. Clay Brown, Somnath Dutta, Jamie Konwerski, Joyce Jose, Thomas J. Jurkiw, James DelProposto, Craig M. Ogata, Georgios Skiniotis, Richard J. Kuhn, Janet L. Smith, "Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System," Science 343, 881-885 (2014). DOI: 10.1126/science.1247749 Cited 215 times

Stephen P. Zano, Alexander G. Pavlovsky, Ronald E. Viola, "Structure of an unusual S-adenosylme­thionine synthetase from Campylobacter jejuni," Acta Crystallogr. D 70 (2), 422-450 (2014). DOI: 10.1107/S139900471303023X Cited 4 times

Jingjun Hong, Hanqiao Feng, Feng Wang, Anand Ranjan, Jianhong Chen, Jiansheng Jiang, Rodolfo Ghirlando, T. Sam Xiao, Carl Wu, Yawen Bai, "The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer," Mol. Cell 53 (3), 498-505 (2014). DOI: 10.1016/j.molcel.2014.01.010 Cited 54 times

Jessica F. Bruhn, Katherine C. Barnett, Jaclyn Bibby, Jens M.H. Thomas, Ronan M. Keegan, Daniel J. Rigden, Zachary A. Bornholdt, Erica Ollmann Saphire, "Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain," J. Virol. 88 (1), 758-762 (2014). DOI: 10.1128/JVI.02294-13 Cited 47 times

Jingzhi Li, Kimberly F. Jaimes, Stephen G. Aller, "Refined structures of mouse P-glycoprotein," Protein Sci. 23 (1), 34-46 (2014). DOI: 10.1002/pro.2387 Cited 261 times

Åge Aleksander Skjevik, Mauro Mileni, Anne Baumann, Øyvind Halskau, Knut Teigen, Raymond C. Stevens, Aurora Martinez, "The N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and Membranes," J. Mol. Biol. 426 (1), 150-168 (2014). DOI: 10.1016/j.jmb.2013.09.012 Cited 22 times

Kevin K. Desai, Chin L. Cheng, Craig A. Bingman, George N. Phillips, Jr, Ronald T. Raines, "A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation," Nucleic Acids Res. 42 (6), 3931-3942 (2014). DOI: 10.1093/nar/gkt1375 Cited 28 times

Robert P. de Vries, Xueyong Zhu, Ryan McBride, Alan Rigter, Anthony Hanson, Gongxun Zhong, Masato Hatta, Rui Xu, Wenli Yu, Yoshihiro Kawaoka, Cornelis A.M. de Haan, Ian A. Wilson, James C. Paulson, "Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses," J. Virol. 88 (1), 768-773 (2014). DOI: 10.1128/JVI.02690-13 Cited 50 times

Engin Özkan, Poh Hui Chia, Ruiqi Rachel Wang, Natalia Goriatcheva, Dominika Borek, Zbyszek Otwinowski, Thomas Walz, Kang Shen, K. Christopher Garcia, "Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis," Cell 156 (3), 482-494 (2014). DOI: 10.1016/j.cell.2014.01.004 Cited 46 times

Cheryl A. Kreinbring, Stephen P. Remillard, Paul Hubbard, Heather R. Brodkin, Finian J. Leeper, Dan Hawksley, Elaine Y. Lai, Chandler Fulton, Gregory A. Petsko, Dagmar Ringe, "Structure of a eukaryotic thiaminase I," Proc. Natl. Acad. Sci. USA 111 (1), 137-142 (2014). DOI: 10.1073/pnas.1315882110 Cited 8 times

Salette Martinez, Rui Wu, Ruslan Sanishvili, Dali Liu, Richard Holz, "The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile," J. Am. Chem. Soc. 136 (4), 1186-1189 (2014). DOI: 10.1021/ja410462j Cited 47 times

Greg A. Snyder, Daniel Deredge, Anna Waldhuber, Theresa Fresquez, David Z. Wilkins, Patrick T. Smith, Susi Durr, Christine Cirl, Jiansheng Jiang, William Jennings, Timothy Luchetti, Nathaniel Snyder, Eric J. Sundberg, Patrick Wintrode, Thomas Miethke, T. Sam Xiao, "Crystal Structures of the Toll/Interleukin-1 Receptor (TIR) Domains from the Brucella Protein TcpB and Host Adaptor TIRAP Reveal Mechanisms of Molecular Mimicry," J. Biol. Chem. 289 (2), 669-679 (2014). DOI: 10.1074/jbc.M113.523407 Cited 49 times

Lei Sun, Lindsey N. Young, Xinzheng Zhang, Sergei P. Boudko, Andrei Fokine, Erica Zbornik, Aaron P. Roznowski, Ian J. Molineux, Michael G. Rossmann, Bentley A. Fane , "Icosahedral bacteriophage [phi]X174 forms a tail for DNA transport during infection," Nature 505, 432-435 (2014). DOI: 10.1038/nature12816 Cited 68 times

Annie Jespersen, Nami Tajima, Gabriela Fernandez-Cuervo, Ethel C. Garnier-Amblard, Hiro Furukawa, "Structural Insights into Competitive Antagonism in NMDA Receptors," Neuron 81 (2), 366-378 (2014). DOI: 10.1016/j.neuron.2013.11.033 Cited 59 times

Wenyu Yu, David Smil, Fengling Li, Wolfram Tempel, Oleg Fedorov, Kong T. Nguyen, Yuri Bolshan, Rima Al-Awar, Stefan Knapp, Cheryl H. Arrowsmith, Masoud Vedadi, Peter J. Brown, Matthieu Schapira, "Bromo-deaza-SAH: A potent and selective DOT1L inhibitor," Bioorgan. Med. Chem. 21, 1787-1794 (2013). DOI: 10.1016/j.bmc.2013.01.049 Cited 54 times

Robert F. Fischetti, Derek Yoder, Shenglan Xu, Oleg Makarov, Craig Ogata, Janet L. Smith, "Predicted optical performance of the GM/CA@APS micro-focus beamline," J. Phys. Conf. Series 425 (1), 012006-1- 012006-6 (2013). DOI: 10.1088/1742-6596/425/1/012006

S. Xu, C.M. Ogata, O. Makarov, S. Corcoran, D. Ferguson, R.F. Fischetti, "Performance of the Compact Visual Beam Imaging System on the GM/CA BM Beamline at the APS," J. Phys. Conf. Series 425 (1), 012016-1-012016-4 (2013). DOI: 10.1088/1742-6596/425/1/012016

S. Stepanov, M. Hilgart, O. Makarov, S.B. Pothineni, D. Yoder, C. Ogata, R. Sanishvili, N. Venugopalan, M. Becker, M. Clift, J.L. Smith, R.F. Fischetti, "JBluIce-EPICS: a fast and flexible open-source beamline control system for macromolecular crystallography," J. Phys. Conf. Series 425 (1), 012019-1-012019-4 (2013). DOI: 10.1088/1742-6596/425/1/012019

Erik Yukl, "Paul D. Boyer and James B. Peter Postdoctoral Award in Biochemistry," (2013).

Peder Cedervall, "Ross A. Gortner Predoctoral Fellowship in Biochemistry," (2013).

Partho Ghosh, "Fellow of American Society of Microbiology," (2013).

Youxing Jiang, "Edith and Peter O’Donnell Awards, the Academy of Medicine, Engineering & Science of Texas," (2013).

Ian M. Slaymaker, Yang Fu, Daniel B. Toso, Nimna Ranatunga, Aaron Brewster, Susan L. Forsburg, Z. Hong Zhou, Xiaojiang S. Chen, "Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology," Nucleic Acids Res. 41 (5), 3446-3456 (2013). DOI: 10.1093/nar/gkt022 Cited 24 times

Michael Lofgren, Dominique Padovani, Markos Koutmos, Ruma Banerjee, "A switch III motif relays signaling between a B[subscript 12] enzyme and its G-protein chaperone," Nat. Chem. Biol. 9, 535-539 (2013). DOI: 10.1038/nchembio.1298 Cited 14 times

Jieqing Zhu, Jianghai Zhu, Timothy A. Springer, "Complete Integrin Headpiece Opening in Eight Steps," J. Cell Biol. 201 (7), 1053-1068 (2013). DOI: 10.1083/JCB.201212037 Cited 134 times

Yongheng Chen, Xiaojun Zhang, Ana Carolina Dantas Machado, Yuan Ding, Zhuchu Chen, Peter Z. Qin, Remo Rohs, Lin Chen, "Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion," Nucleic Acids Res. 41 (17), 8368-8376 (2013). DOI: 10.1093/nar/gkt584 Cited 46 times

Siyang Sun, Ye Xiang, Wataru Akahata, Heather Holdaway, Pankaj Pal, Xinzheng Zhang, Michael S. Diamond, Gary J. Nabel, Michael G. Rossmann, "Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization," eLIFE J. 2013, e00435-1-e00435-27 (2013). DOI: 10.7554/eLife.00435.001 Cited 92 times

John Gilchrist, Samir Das, Filip Van Petegem, Frank Bosmans, "Crystallographic insights into sodium-channel modulation by the [beta]4 subunit," Proc. Natl. Acad. Sci. USA 110 (51), E5016-E5024 (2013). DOI: 10.1073/pnas.1314557110 Cited 64 times

Vidya Mangala Prasad, Steven D. Willows, Andrei Fokine, Anthony J. Battisti, Siyang Sun, Pavel Plevka, Tom C. Hobman, Michael G. Rossmann, "Rubella virus capsid protein structure and its role in virus assembly and infection," Proc. Natl. Acad. Sci. USA 110 (50), 20105-20110 (2013). DOI: 10.1073/pnas.1316681110 Cited 24 times

Denise A. McGrath, Eva Rose M. Balog, Mardo Kõivomägi, Rafael Lucena, Michelle V. Mai, Alexander Hirschi, Douglas R. Kellogg, Mart Loog, Seth M. Rubin , "Cks confers specificity to phosphorylation-dependent CDK signaling pathways," Nat. Struct. Mol. Biol. 20 (12), 1407-1414 (2013). DOI: 10.1038/nsmb.2707 Cited 48 times

Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Celine Valant, Patrick M. Sexton, Arthur Christopoulos, Christian C. Felder, Peter Gmeiner, Jan Steyaert, William I. Weis, K. Christopher Garcia, Jürgen Wess, Brian K. Kobilka , "Activation and allosteric modulation of a muscarinic acetylcholine receptor," Nature 504, 101-106 (2013). DOI: 10.1038/nature12735 Cited 604 times

Jean-Philippe Julien, Albert Cupo, Devin Sok, Robyn L. Stanfield, Dmitry Lyumkis, Marc C. Deller, Per-Johan Klasse, Dennis R. Burton, Rogier W. Sanders, John P. Moore, Andrew B. Ward, Ian A. Wilson, "Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer," Science 342, 1477-1483 (2013). DOI: 10.1126/science.1245625 Cited 632 times

Yunji Wu, Anthony P. West, Jr., Helen J. Kim, Matthew E. Thornton, Andrew B. Ward, Pamela J. Bjorkman, "Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12," Cell Reports 5 (5), 1443-1455 (2013). DOI: 10.1016/j.celrep.2013.11.015 Cited 20 times

Rui Xu, Robert P. de Vries, Xueyong Zhu, Corwin M. Nycholat, Ryan McBride, Wenli Yu, James C. Paulson, Ian A. Wilson, "Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses," Science 342, 1230-1235 (2013). DOI: 10.1126/science.1243761 Cited 117 times

Beatriz Trastoy, Joseph V. Lomino, Lai-Xi Wang, Eric J. Sundberg, "Liquid-liquid diffusion crystallization improves the X-ray diffraction of EndoS, an endo-[beta]-N-acetyl­glucosaminidase from Streptococcus pyogenes with activity on human IgG," Acta Crystallogr. F 69 (12), 1405-1410 (2013). DOI: 10.1107/S1744309113030650 Cited 5 times

Geng Meng, Xinzheng Zhang, Pavel Plevka, Qian Yu, Peter Tijssen, Michael G. Rossmann, "The Structure and Host Entry of an Invertebrate Parvovirus," J. Virol. 87 (23), 12523-12530 (2013). DOI: 10.1128/JVI.01822-13 Cited 11 times

Xueyong Zhu, Yong-Hui Guo, Tao Jiang, Ya-Di Wang, Kwok-Hung Chan, Xiao-Feng Li, Wenli Yu, Ryan McBride, James C. Paulson, Kwok-Yung Yuen, Cheng-Feng Qin, Xiao-Yan Che, Ian A. Wilson, "A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin," J. Virol. 87 (23), 12619-12635 (2013). DOI: 10.1128/JVI.01577-13 Cited 35 times

Weihe Zhang, Andrew L. McIver, Michael A. Stashko, Deborah DeRyckere, Brian R. Branchford, Debra Hunter, Dmitri Kireev, Michael J. Miley, Jacqueline Norris-Drouin, Wendy M. Stewart, Minjung Lee, Susan Sather, Yingqiu Zhou, Jorge A. Di Paola, Mischa Machius, William P. Janzen, H. Shelton Earp, Douglas K. Graham, Stephen V. Frye, Xiaodong Wang, "Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis," J. Med. Chem. 56 (23), 9693-9700 (2013). DOI: 10.1021/jm4013888 Cited 35 times

Adrienne M. Luoma, Caitlin D. Castro, Toufic Mayassi, Leslie A. Bembinster, Li Bai, Damien Picard, Brian Anderson, Louise Scharf, Jennifer E. Kung, Leah V. Sibener, Paul B. Savage, Bana Jabri, Albert Bendelac, Erin J. Adams, "Crystal Structure of V[delta]1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human [gamma delta] T Cells," Immunity 39 (6), 1032-1042 (2013). DOI: 10.1016/j.immuni.2013.11.001 Cited 158 times

Yamei Yu, Thomas Schürpf, Timothy A. Springer, "How Natalizumab Binds and Antagonizes [alpha subscript 4] Integrins," J. Biol. Chem. 288 (45), 32314-32325 (2013). DOI: 10.1074/jbc.M113.501668 Cited 44 times

Sunil Kumar Tewary, Haiyan Zhao, Weiran Shen, Jianming Qiu, Liang Tang, "Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human Bocavirus," J. Virol. 87 (21), 11487-11493 (2013). DOI: 10.1128/JVI.01770-13 Cited 21 times

Michael L. Oldham, Shanshuang Chen, Jue Chen, "Structural basis for substrate specificity in the Escherichia coli maltose transport system," Proc. Natl. Acad. Sci. USA 110 (45), 18132-18137 (2013). DOI: 10.1073/pnas.1311407110 Cited 56 times

Min Lu, Martha Radchenko, Jindrich Symersky, Rongxin Nie, Yi Guo , "Structural insights into H[superscript +]-coupled multidrug extrusion by a MATE transporter," Nat. Struct. Mol. Biol. 20 (11), 1310-1317 (2013). DOI: 10.1038/nsmb.2687 Cited 73 times

Balasundaresan Dhakshnamoorthy, Brigitte K. Ziervogel, Lydia Blachowicz, Benoît Roux, "A Structural Study of Ion Permeation in OmpF Porin from Anomalous X-ray Diffraction and Molecular Dynamics Simulations," J. Am. Chem. Soc. 135 (44), 16561-16568 (2013). DOI: 10.1021/ja407783a Cited 14 times

Jacinto López-Sagaseta, Charles L. Dulberger, Amanda McFedries, Mark Cushman, Alan Saghatelian, Erin J. Adams, "MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1," J. Immunol. 191 (10), 5268-5277 (2013). DOI: 10.4049/jimmunol.1301958 Cited 58 times

Jiliang Liu, Hideyo Inouye, Nagarajan Venugopalan, Robert F. Fischetti, S. Charlotte Gleber, Stefan Vogt, Joanne C. Cusumano, Jeong Im Kim, Clint Chapple, Lee Makowski, "Tissue specific specialization of the nanoscale architecture of Arabidopsis," J. Struct. Biol. 184 (2), 103-114 (2013). DOI: 10.1016/j.jsb.2013.09.013 Cited 8 times

Mehmet Sen, Koichi Yuki, Timothy A. Springer, "An internal ligand-bound, metastable state of a leukocyte integrin, [alpha subscript x beta subscript 2]," J. Cell Biol. 203 (4), 629 (2013). DOI: 10.1083/jcb.201308083 Cited 51 times

Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean- Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F. Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth P.St. John, Po-Ying Chan-Hui, Kristine Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard, "The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies," PLoS Patho. 9 (11), e1003754-1-e1003754-20 (2013). DOI: 10.1371/journal.ppat.1003754 Cited 136 times

Jonathan R. Whicher, Sarah S. Smaga, Douglas A. Hansen, William C. Brown, William H. Gerwick, David H. Sherman, Janet L. Smith, "Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis," Chem. Biol. 20 (11), 1340-1351 (2013). DOI: 10.1016/j.chembiol.2013.09.015 Cited 70 times

David B. Sauer, Weizhong Zeng, John Canty, Yeeling Lam, Youxing Jiang , "Sodium and potassium competition in potassium-selective and non-selective channels," Nat. Commun. 4, 2721-1-2721-7 (2013). DOI: 10.1038/ncomms3721 Cited 43 times

Minsun Hong, Peter S. Lee, Ryan M.B. Hoffman, Xueyong Zhu, Jens C. Krause, Nick S. Laursen, Sung-il Yoon, Langzhou Song, Lynda Tussey, James E. Crowe, Jr., Andrew B. Ward, Ian A. Wilson, "Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site," J. Virol. 87 (22), 12471-12480 (2013). DOI: 10.1128/JVI.01388-13 Cited 103 times

John Edward Pak, Elisabeth Ngonlong Ekendé, Efrem G. Kifle, Joseph Daniel O’Connell III, Fabien De Angelis, Meseret B. Tessema, Kheiro-Mouna Derfoufi, Yaneth Robles-Colmenares, Rebecca A. Robbins, Erik Goormaghtigh, Guy Vandenbussche, Robert M. Stroud, "Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter," Proc. Natl. Acad. Sci. USA 110 (46), 18484-18489 (2013). DOI: 10.1073/pnas.1318705110 Cited 31 times

Shuaiqi Guo, Christopher P. Garnham†, Sarathy Karunan Partha, Robert L. Campbell, John S. Allingham, Peter L. Davies, "Role of Ca[superscript 2+] in folding the tandem [beta]-sandwich extender domains of a bacterial ice-binding adhesin," FEBS J. 280 (22), 5919-5932 (2013). DOI: 10.1111/febs.12518 Cited 18 times

Gira Bhabha, Damian C. Ekiert, Madeleine Jennewein, Christian M. Zmasek, Lisa M. Tuttle, Gerard Kroon, H. Jane Dyson, Adam Godzik, Ian A. Wilson, Peter E. Wright , "Divergent evolution of protein conformational dynamics in dihydrofolate reductase," Nat. Struct. Mol. Biol. 20 (11), 1243-1249 (2013). DOI: 10.1038/nsmb.2676 Cited 93 times

Hong Wu, Alena Siarheyeva, Hong Zeng, Robert Lam, Aiping Dong, Xian-Hui Wu, Yanjun Li, Matthieu Schapira, Masoud Vedadi, Jinrong Min, "Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2," FEBS Lett. 587 (23), 3859-3868 (2013). DOI: 10.1016/j.febslet.2013.10.020 Cited 28 times

Suxiang Tong, Xueyong Zhu, Yan Li, Mang Shi, Jing Zhang, Melissa Bourgeois, Hua Yang, Xianfeng Chen, Sergio Recuenco, Jorge Gomez, Li-Mei Chen, Adam Johnson, Ying Tao, Cyrille Dreyfus, Wenli Yu, Ryan McBride, Paul J. Carney, Amy T. Gilbert, Jessie Chang, Zhu Guo, Charles T. Davis, James C. Paulson, James Stevens, Charles E. Rupprecht, Edward C. Holmes, Ian A. Wilson, Ruben O. Donis, "New World Bats Harbor Diverse Influenza A Viruses," PLoS Patho. 9 (10), e1003657-1-e1003657-12 (2013). DOI: 10.1371/journal.ppat.1003657 Cited 794 times

Gulcin Gulten, James C. Sacchettini, "Structure of the Mtb CarD/RNAP [beta]-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD," Structure 21 (10), 1859-1869 (2013). DOI: 10.1016/j.str.2013.08.014 Cited 27 times

Aaron M. Ring, Aashish Manglik, Andrew C. Kruse, Michael D. Enos, William I. Weis, K. Christopher Garcia, Brian K. Kobilka , "Adrenaline-activated structure of [beta subscript 2]-adrenoceptor stabilized by an engineered nanobody," Nature 502, 575-579 (2013). DOI: 10.1038/nature12572 Cited 316 times

Michael Lofgren, Markos Koutmos, Ruma Banerjee, "Autoinhibition and Signaling by the Switch II Motif in the G-protein Chaperone of a Radical B[subscript 12] Enzyme," J. Biol. Chem. 288, 30980-30989 (2013). DOI: 10.1074/jbc.M113.499970 Cited 8 times

Cherilyn M. Sirois, Tengchuan Jin, Allison L. Miller, Damien Bertheloot, Hirotaka Nakamura, Gabor L. Horvath, Abubakar Mian, Jiansheng Jiang, Jacob Schrum, Lukas Bossaller, Karin Pelka, Natalio Garbi, Yambasu Brewah, Jane Tian, ChewShun Chang, Partha S. Chowdhury, Gary P. Sims, Roland Kolbeck, Anthony J. Coyle, Alison A. Humbles, T. Sam Xiao, Eicke Latz, "RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA," J. Exp. Med. 210 (11), 2447-2463 (2013). DOI: 10.1084/jem.20120201 Cited 135 times

Alaina L. Garland, William G. Walton, Raymond D. Coakley, Chong D. Tan, Rodney C. Gilmore, Carey A. Hobbs, Ashutosh Tripathy, Lucy A. Clunes, Sompop Bencharit, M. Jackson Stutts, Laurie Betts, Matthew R. Redinbo, Robert Tarran, "Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways," Proc. Natl. Acad. Sci. USA 110 (40), 15973-15978 (2013). DOI: 10.1073/pnas.1311999110 Cited 136 times

Nadine Czudnochowski, Amy Liya Wang, Janet Finer-Moore, Robert M. Stroud, "In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities," J. Mol. Biol. 425 (20), 3875-3887 (2013). DOI: 10.1016/j.jmb.2013.05.014 Cited 18 times

John Badger, Jyotsana Lal, Ross Harder, Hideyo Inouye, S. Charlotte Gleber, Stefan Vogt, Ian Robinson, Lee Makowski, "Three-dimensional Imaging of Crystalline Inclusions Embedded in Intact Maize Stalks," Sci. Rep. 3, 2843-1-2843-5 (2013). DOI: 10.1038/srep02843 Cited 3 times

Kenneth D. Clevenger, Rui Wu, Joyce A.V. Er, Dali Liu, Walter Fast, "Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme," ACS Chem. Biol. 8 (10), 2192-2200 (2013). DOI: 10.1021/cb400345h Cited 28 times

Fabienne Furt, William J. Allen, Joshua R. Widhalm, Peter Madzelan, Robert C. Rizzo, Gilles Basset, Mark A. Wilson, "Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis," Acta Crystallogr. D 69 (10), 1876-1888 (2013). DOI: 10.1107/S0907444913015771 Cited 6 times

Kabirul Islam, Yuling Chen, Hong Wu, Ian R. Bothwell, Gil J. Blum, Hong Zeng, Aiping Dong, Weihong Zheng, Jinrong Min, Haiteng Deng, Minkui Luo, "Defining efficient enzyme–cofactor pairs for bioorthogonal profiling of protein methylation," Proc. Natl. Acad. Sci. USA 110 (42), 16778-16783 (2013). DOI: 10.1073/pnas.1216365110 Cited 51 times

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Yamei Yu, Jianghai Zhu, Po-Ssu Huang, Jia-huai Wang, Nick Pullen, Timothy A. Springer, "Domain 1 of Mucosal Addressin Cell Adhesion Molecule Has an I1-set Fold and a Flexible Integrin-binding Loop," J. Biol. Chem. 288 (9), 6284-6294 (2013). DOI: 10.1074/jbc.M112.413153 Cited 5 times

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Megan K. Murphy, Ling Yue, Ruimin Pan, Saikat Boliar, Anurag Sethi, Jianhui Tian, Katja Pfafferot, Etienne Karita, Susan A. Allen, Emmanuel Cormier, Paul A. Goepfert, Persephone Borrow, James E. Robinson, S. Gnanakaran, Eric Hunter, Xiang-Peng Kong, Cynthia A. Derdeyn, "Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth," PLoS Patho. 9 (2), e1003173-1-e1003173-20 (2013). DOI: 10.1371/journal.ppat.1003173 Cited 36 times

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Chloe M. Adams, Brian E. Eckenroth, Emily E. Putnam, Sylvie Doublié, Aimee Shen, "Structural and Functional Analysis of the CspB Protease Required for Clostridium Spore Germination," PLoS Patho. 9 (2), e1003165-1-e1003165-17 (2013). DOI: 10.1371/journal.ppat.1003165 Cited 75 times

Mikalai Lapkouski, Lan Tian, Jennifer T. Miller, Stuart F.J. Le Grice, Wei Yang, "Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation," Nat. Struct. Mol. Biol. 20 (2), 230-236 (2013). DOI: 10.1038/nsmb.2485 Cited 63 times

Jonathan S. Edwards, Laurie Betts, Monica L. Frazier, Rebecca M. Pollet, Stephen M. Kwong, William G. Walton, W. Keith Ballentine, III, Julianne J. Huang, Sohrab Habibi, Mark Del Campo, Jordan L. Meier, Peter B. Dervan, Neville Firth, Matthew R. Redinbo, "Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus," Proc. Natl. Acad. Sci. USA 110 (8), 2804-2809 (2013). DOI: 10.1073/pnas.1219701110 Cited 35 times

Christopher C. Goulah, Guangyu Zhu, Mary Koszelak-Rosenblum, Michael G. Malkowski, "The Crystal Structure of [alpha]-Dioxygenase Provides Insight into Diversity in the Cyclooxygenase-Peroxidase Superfamily," Biochemistry-US 52 (8), 1364-1372 (2013). DOI: 10.1021/bi400013k Cited 15 times

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Visaahini Sureshan, Chandrika N. Deshpande, Yan Boucher, Jeremy E. Koenig, H.W. Stokes, Stephen J. Harrop, Paul M.G. Curmi, Bridget C. Mabbutt, "Integron Gene Cassettes: A Repository of Novel Protein Folds with Distinct Interaction Sites," PLoS One 8 (1), e52934-1-e52934-13 (2013). DOI: 10.1371/journal.pone.0052934 Cited 10 times

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Baikuntha P. Aryal, Pedro Brugarolas, Chuan He, "Binding of ReO[subscript 4]− with an engineered MoO[subscript 4 superscript 2]−-binding protein: towards a new approach in radiopharmaceutical applications," J. Biol. Inorg. Chem. 17 (1), 97-106 (2012). DOI: 10.1007/s00775-011-0833-4 Cited 11 times

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Jin H. Park, Yingting Liu, Mark A. Lemmon, Ravi Radhakrishnan, "Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain," Biochem. J. 448 (3), 417-423 (2012). DOI: 10.1042/BJ20121513 Cited 118 times

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Jim F. White, Nicholas Noinaj, Yoko Shibata, James Love, Brian Kloss, Feng Xu, Jelena Gvozdenovic-Jeremic, Priyanka Shah, Joseph Shiloach, Christopher G. Tate, Reinhard Grisshammer, "Structure of the agonist-bound neurotensin receptor," Nature 490, 508-513 (2012). DOI: 10.1038/nature11558 Cited 365 times

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Xueyong Zhu, Ryan McBride, Corwin M. Nycholat, Wenli Yu, James C. Paulson, Ian A. Wilson, "Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors," J. Virol. 86 (24), 13371-13383 (2012). DOI: 10.1128/JVI.01426-12 Cited 89 times

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Jennifer Gehret McCarthy, Eli B. Eisman, Sarang Kulkarni, Lena Gerwick, William H. Gerwick, Peter Wipf, David H. Sherman, Janet L. Smith, "Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways," ACS Chem. Biol. 7 (12), 1994-2003 (2012). DOI: 10.1021/cb300385m Cited 23 times

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Donald D. Raymond, Mary E. Piper, Sonja R. Gerrard, Georgios Skiniotis, Janet L. Smith, "Phleboviruses encapsidate their genomes by sequestering RNA bases," Proc. Natl. Acad. Sci. USA 109 (47), 19208-19213 (2012). DOI: 10.1073/pnas.1213553109 Cited 68 times

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Marie V. Wong, Paaventhan Palasingam, Prasanna R. Kolatkar, "Cloning, purification and preliminary X-ray data analysis of the human ID2 homodimer," Acta Crystallogr. F 68 (11), 1354-1358 (2012). DOI: 10.1107/S174430911203895X Cited 2 times

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Mi Sun Jin, Michael L. Oldham, Qiuju Zhang, Jue Chen, "Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans," Nature 490, 566-569 (2012). DOI: 10.1038/nature11448 Cited 351 times

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Hexin Xie, Joseph Mire, Ying Kong, MiHee Chang, Hany A. Hassounah, Chris N. Thornton, James C. Sacchettini, Jeffrey D. Cirillo, Jianghong Rao, "Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe," Nat. Chem. 4, 802-809 (2012). DOI: 10.1038/nchem.1435 Cited 113 times

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Jacinto Lopez-Sagaseta, Jennifer E. Kung, Paul B. Savage, Jenny Gumperz, Erin J. Adams, "The Molecular Basis for Recognition of CD1d/[alpha]- Galactosylceramide by a Human Non-V[alpha]a24 T Cell Receptor," PLoS Biol. 10 (10), e1001412-1-e1001412-11 (2012). DOI: 10.1371/journal.pbio.1001412 Cited 19 times

Peter S. Lee, Reiko Yoshida, Damian C. Ekiert, Naoki Sakai, Yasuhiko Suzuki, Ayato Takada, Ian A. Wilson, "Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity," Proc. Natl. Acad. Sci. USA 109 (42), 17040-17045 (2012). DOI: 10.1073/pnas.1212371109 Cited 111 times

Elwood A. Mullins, T. Joseph Kappock, "Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases," Biochemistry-US 51 (42), 8422-8434 (2012). DOI: 10.1021/bi300957f Cited 16 times

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Aparna Palakodeti, Andrew Sandstrom, Lakshmi Sundaresan, Christelle Harly, Steven Nedellec, Daniel Olive, Emmanuel Scotet, Marc Bonneville, Erin J. Adams, "The Molecular Basis for Modulation of Human V[gamma]9V[delta]2 T Cell Responses by CD277/Butyrophilin-3 (BTN3A)-specific Antibodies," J. Biol. Chem. 287 (39), 32780-32790 (2012). DOI: 10.1074/jbc.M112.384354 Cited 106 times

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Ping Liu, Thomas E. Cleveland IV, Samuel Bouyain, Patrick O. Byrne, Patti A. Longo, Daniel J. Leahy, "A single ligand is sufficient to activate EGFR dimers," Proc. Natl. Acad. Sci. USA 109 (27), 10861-10866 (2012). DOI: 10.1073/pnas.1201114109 Cited 82 times

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Leopold Kong, Erick Giang, Justin B. Robbins, Robyn L. Stanfield, Dennis R. Burton, Ian A. Wilson, Mansun Law, "Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1," Proc. Natl. Acad. Sci. USA 109 (24), 9499-9504 (2012). DOI: 10.1073/pnas.1202924109 Cited 111 times

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Darya V. Urusova, Jung-Hyun Shim, Dong Joon Kim, Sung Keun Jung, Tatyana A. Zykova, Andria Carper, Ann M. Bode, Zigang Dong, "Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1," Cancer Prev. Res. 4, 1366-1377 (2011). DOI: 10.1158/1940-6207.CAPR-11-0301 Cited 88 times

Brandon Goblirsch, "Pauling Poster Prize," (2011).

Peder Cedervall, "Victor A. Bloomfield Fellowship," (2011).

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Anastasia A. Aksyuk, Lidia P. Kurochkina, Andrei Fokine, Farhad Forouhar, Vadim V. Mesyanzhinov, Liang Tong, Michael G. Rossmann, "Structural Conservation of the Myoviridae Phage Tail Sheath Protein Fold," Structure 19 (12), 1885-1894 (2011). DOI: 10.1016/j.str.2011.09.012 Cited 33 times

Tomoyasu Ishikawa, Masaki Seto, Hiroshi Banno, Youichi Kawakita, Mami Oorui, Takahiko Taniguchi, Yoshikazu Ohta, Toshiya Tamura, Akiko Nakayama, Hiroshi Miki, Hidenori Kamiguchi, Toshimasa Tanaka, Noriyuki Habuka, Satoshi Sogabe, Jason Yano, Kathleen Aertgeerts, Keiji Kamiyama, "Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold," J. Med. Chem. 54 (23), 8030-8050 (2011). DOI: 10.1021/jm2008634 Cited 126 times

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Mary Khanna, Che-Hong Chen, Ann Kimble-Hill, Bibek Parajuli, Samantha Perez-Miller, Sulochanadevi Baskaran, Jeewon Kim, Karl Dria, Vasilis Vasiliou, Daria Mochly-Rosen, Thomas D. Hurley, "Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases," J. Biol. Chem. 286 (50), 43486-43494 (2011). DOI: 10.1074/jbc.M111.293597 Cited 53 times

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P. Benjamin Stranges, Mischa Machius, Michael J. Miley, Ashutosh Tripathy, Brian Kuhlman, "Computational design of a symmetric homodimer using [beta]-strand assembly," Proc. Natl. Acad. Sci. USA 108 (51), 20562-20567 (2011). DOI: 10.1073/pnas.1115124108 Cited 59 times

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Karl E. Zahn, April Averill, Susan S. Wallace, Sylvie Doublié, "The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site," Biochemistry-US 50 (47), 10350-10358 (2011). DOI: 10.1021/bi201219s Cited 15 times

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Byung Woo Han, Thomas E. Malone, Do Jin Kim, Craig A. Bingman, Hyun-Jung Kim, Brian G. Fox, George N. Phillips Jr., "Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A[subscript 1]," Proteins 79 (11), 3236-3241 (2011). DOI: 10.1002/prot.23153 Cited 2 times

Stephen M. Smith, Swati Rawat, Joshua Telser, Brian M. Hoffman, Timothy L. Stemmler, Amy C. Rosenzweig, "Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M," Biochemistry-US 50 (47), 10231-10240 (2011). DOI: 10.1021/bi200801z Cited 86 times

Claudiu M. Nelersa, Brad J. Schmier, Arun Malhotra, "Purification and crystallization of Bacillus subtilis NrnA, a novel enzyme involved in nanoRNA degradation," Acta Crystallogr. F 67 (10), 1235-1238 (2011). DOI: 10.1107/S1744309111026509 Cited 4 times

David B. Sauer, Weizhong Zeng, Srinivasan Raghunathan, Youxing Jiang, "Protein interactions central to stabilizing the K[superscript +] channel selectivity filter in a four-sited configuration for selective K[superscript +] permeation," Proc. Natl. Acad. Sci. USA 108 (40), 16634-16639 (2011). DOI: 10.1073/pnas.1111688108 Cited 32 times

S. Xu, V. Nagarajan, R.F. Fischetti, "Design and manufacture of mini-beam collimators for macromolecular crystallography at the GM/CA-CAT at APS," Diamond Light Source Proceedings, MEDSI-6 , Diamond Light Source, (2011), e27-1 - e27-4. DOI: 10.1017/S2044820110000353

Paola Sette, Ruiling Mu, Vincent Dussupt, Jiansheng Jiang, Greg Snyder, Patrick Smith, Tsan Sam Xiao, Fadila Bouamr, "The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release," Structure 19 (10), 1485-1495 (2011). DOI: 10.1016/j.str.2011.07.016 Cited 21 times

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Brian Bae, Ryan E. Cobb, Matthew A. DeSieno, Huimin Zhao, Satish K. Nair, "New N-Acetyltransferase Fold in the Structure and Mechanism of the Phosphonate Biosynthetic Enzyme FrbF," J. Biol. Chem. 286 (41), 36132-36141 (2011). DOI: 10.1074/jbc.M111.263533 Cited 8 times

David L. Akey, Shengying Li, Jamie R. Konwerski, Laura A. Confer, Steffen M. Bernard, Yojiro Anzai, Fumio Kato, David H. Sherman, Janet L. Smith, "A New Structural Form in the SAM/Metal-Dependent O‑Methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway," J. Mol. Biol. 413 (2), 438-450 (2011). DOI: 10.1016/j.jmb.2011.08.040 Cited 13 times

Aram Chang, Shanteri Singh, Kate E. Helmich, Randal D. Goff, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr., "Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity," Proc. Natl. Acad. Sci. USA 108 (43), 17649-17654 (2011). DOI: 10.1073/pnas.1108484108 Cited 37 times

Kimihisa Yoshida, Hyuk-Soo Seo, Erik W. Debler, Günter Blobel, André Hoelz, "Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex," Proc. Natl. Acad. Sci. USA 108 (40), 16571-16576 (2011). DOI: 10.1073/pnas.1112846108 Cited 42 times

Nafez Abu Tarboush, Lyndal M.R. Jensen, Erik T. Yukl, Jiafeng Geng, Aimin Liu, Carrie M. Wilmot, Victor L. Davidson, "Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis," Proc. Natl. Acad. Sci. USA 108 (41), 16956-16961 (2011). DOI: 10.1073/pnas.1109423108 Cited 51 times

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Michael L. Oldham, Jue Chen, "Snapshots of the maltose transporter during ATP hydrolysis," Proc. Natl. Acad. Sci. USA 108 (37), 15152-15156 (2011). DOI: 10.1073/pnas.1108858108 Cited 141 times

Pierre Aller, Stéphanie Duclos, Susan S. Wallace, Sylvie Doublié, "A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex," J. Mol. Biol. 412 (1), 22-34 (2011). DOI: 10.1016/j.jmb.2011.07.007 Cited 22 times

Derek W. Yoder, Oleg Makarov, Stephen Corcoran, Robert F. Fischetti, "PID feedback control of monochromator thermal stabilization," Nucl. Instrum. Methods A 649 (1), 107-108 (2011). DOI: 10.1016/j.nima.2010.11.177 Cited 2 times

Shenglan Xu, Lisa J. Keefe, Anne Mulichak, Lifen Yan, Ercan E. Alp, Jiyong Zhao, Robert F. Fischetti, "Mini-beam collimator applications at the Advanced Photon Source," Nucl. Instrum. Methods A 649 (1), 104-106 (2011). DOI: 10.1016/j.nima.2010.11.008 Cited 8 times

Mark C. Hilgart, Ruslan Sanishvili, Craig M. Ogata, Michael Becker, Nagarajan Venugopalan, Sergey Stepanov, Oleg Makarov, Janet L. Smith, Robert F. Fischetti, "Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals," J. Synchrotron Rad. 18 (5), 717-722 (2011). DOI: 10.1107/S0909049511029918 Cited 50 times

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Douglas R. Davies, Bart L. Staker, Jan A. Abendroth, Thomas E. Edwards, Robert Hartley, Jess Leonard, Hidong Kim, Amanda L. Rychel, Stephen N. Hewitt, Peter J. Myler, Lance J. Stewart, "An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase," Acta Crystallogr. F 67 (9), 1044-1050 (2011). DOI: 10.1107/S1744309111030405 Cited 18 times

Darren W. Begley, Douglas R. Davies, Robert C. Hartley, Stephen N. Hewitt, Amanda L. Rychel, Peter J. Myler, Wesley C. Van Voorhis, Bart L. Staker, Lance J. Stewart, "Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening," Acta Crystallogr. F 67 (9), 1060-1069 (2011). DOI: 10.1107/S1744309111014436 Cited 7 times

Matthew R. Whorton, Roderick MacKinnon, "Crystal Structure of the Mammalian GIRK2 K[superscript +] Channel and Gating Regulation by G Proteins, PIP[subscript 2], and Sodium," Cell 147 (1), 199-208 (2011). DOI: 10.1016/j.cell.2011.07.046 Cited 300 times

Ning Shi, Weizhong Zeng, Sheng Ye, Yang Li, Youxing Jiang, "Crucial Points within the Pore as Determinants of K[superscript +] Channel Conductance and Gating," J. Mol. Biol. 411 (1), 27-35 (2011). DOI: 10.1016/j.jmb.2011.04.058 Cited 14 times

Sergey Stepanov, Mark Hilgart, Derek W. Yoder, Oleg Makarov, Michael Becker, Ruslan Sanishvili, Craig M. Ogata, Nagarajan Venugopalan, David Aragão, Martin Caffrey, Janet L. Smith, Robert F. Fischetti, "Fast fluorescence techniques for crystallography beamlines," J. Appl. Crystallogr. 44 (4), 772-778 (2011). DOI: 10.1107/S0021889811016748 Cited 13 times

Hiroyuki Tanaka, Miki Senda, Nagarajan Venugopalan, Atsushi Yamamoto, Toshiya Senda, Tetsuo Ishida, Kihachiro Horiike, "Crystal Structure of a Zinc-dependent d-Serine Dehydratase from Chicken Kidney," J. Biol. Chem. 286 (31), 27548-27558 (2011). DOI: 10.1074/jbc.M110.201160 Cited 16 times

Susan P. Yates, Thomas E. Edwards, Cassie M. Bryan, Adam J. Stein, Wesley C. Van Voorhis, Peter J. Myler, Lance J. Stewart, Jimin Zheng, Zongchao Jia, "Structural Basis of the Substrate Specificity of Bifunctional Isocitrate Dehydrogenase Kinase/Phosphatase," Biochem. J. 50 (38), 8103-8106 (2011). DOI: 10.1021/bi200809p Cited 9 times

Johanne Le Coq, Partho Ghosh, "Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement," Proc. Natl. Acad. Sci. USA 108 (35), 14649-14652 (2011). DOI: 10.1073/pnas.1105613108 Cited 27 times

Reza Khayat, Nicholas Brunn, Jeffrey A. Speir, John M. Hardham, Robert G. Ankenbauer, Anette Schneemann, John E. Johnson, "The 2.3-Angstrom Structure of Porcine Circovirus 2," J. Virol. 85 (15), 7856-7862 (2011). DOI: 10.1128/JVI.00737-11 Cited 127 times

Pedro Brugarolas, Erica M. Duguid, Wen Zhang, Catherine B. Poor, Chuan He, "Structural and biochemical characterization of N[superscript 5]-carboxyaminoimidazole ribonucleotide synthetase and N[superscript 5]-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus," Acta Crystallogr. D 67 (8), 707-715 (2011). DOI: 10.1107/S0907444911023821 Cited 8 times

Jennifer Bridwell-Rabb, Andrew M. Winn, David P. Barondeau, "Structure–Function Analysis of Friedreich’s Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex," Biochemistry-US 50 (33), 7265-7274 (2011). DOI: 10.1021/bi200895k Cited 56 times

Sung-il Yoon, Minsun Hong, Ian A Wilson, "An unusual dimeric structure and assembly for TLR4 regulator RP105–MD-1," Nat. Struct. Mol. Biol. 18, 1028-1035 (2011). DOI: 10.1038/nsmb.2106 Cited 47 times

Lee Makowski, David Gore, Suneeta Mandava, David Minh, Sanghyun Park, Diane J. Rodi, Robert F. Fischetti, "X-ray solution scattering studies of the structural diversity intrinsic to protein ensembles," Biopolymers 95 (8), 531-542 (2011). DOI: 10.1002/bip.21631 Cited 27 times

Andrei Fokine, Mohammad Z. Islam, Zhihong Zhang, Valorie D. Bowman, Venigalla B. Rao, Michael G. Rossmann, "Structure of the Three N-Terminal Immunoglobulin Domains of the Highly Immunogenic Outer Capsid Protein from a T4-Like Bacteriophage," J. Virol. 85 (16), 8141-8148 (2011). DOI: 10.1128/JVI.00847-11 Cited 42 times

Monica Ilies, Luigi Di Costanzo, Daniel P. Dowling, Katherine J. Thorn, David W. Christianson, "Binding of [alpha, alpha]-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design," J. Med. Chem. 54 (15), 5432-5443 (2011). DOI: 10.1021/jm200443b Cited 52 times

Markos Koutmos, Carmen Gherasim, Janet L. Smith, Ruma Banerjee, "Structural Basis of Multifunctionality in a Vitamin B[subscript 12]-processing Enzyme," J. Biol. Chem. 286 (34), 29780-29787 (2011). DOI: 10.1074/jbc.M111.261370 Cited 52 times

Xin Liu, David A. Bushnell, Daniel-Adriano Silva, Xuhui Huang, Roger D. Kornberg, "Initiation Complex Structure and Promoter Proofreading," Science 33, 633-637 (2011). DOI: 10.1126/science.1206629 Cited 45 times

Theresa Tiefenbrunn, Wei Liu, Ying Chen, Vsevolod Katritch, C. David Stout, James A. Fee, Vadim Cherezov, "High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment," PLoS One 6 (7), e22348-1-e22348-12 (2011). DOI: 10.1371/journal.pone.0022348 Cited 90 times

Qingping Xu, Neil D. Rawlings, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E. Klock, Mark W. Knuth, Mitchell D. Miller, Marc-Andre Elsliger, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites," PLoS One 6 (7), e22013-1-e22013-10 (2011). DOI: 10.1371/journal.pone.0022013 Cited 15 times

Janesh Kumar, Peter Schuck, Mark L. Mayer, "Structure and Assembly Mechanism for Heteromeric Kainate Receptors," Neuron 71 (2), 319-331 (2011). DOI: 10.1016/j.neuron.2011.05.038 Cited 94 times

Karl E. Zahn, Egor P. Tchesnokov, Matthias Götte, Sylvie Doublié, "Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase," J. Biol. Chem. 286 (28), 25246-25255 (2011). DOI: 10.1074/jbc.M111.248864 Cited 37 times

Nicholas Noinaj, Mary A. Bosserman, M. Alexandra Schickli, Grzegorz Piszczek, Madan K. Kharel, Pallab Pahari, Susan K. Buchanan, Jürgen Rohr, "The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis," J. Biol. Chem. 286 (26), 23533-23543 (2011). DOI: 10.1074/jbc.M111.247833 Cited 18 times

Serdar Uysal, Luis G. Cuello, D. Marien Cortes, Shohei Koide, Anthony A. Kossiakoff, Eduardo Perozo, "Mechanism of activation gating in the full-length KcsA K[superscript +] channel," Proc. Natl. Acad. Sci. USA 108 (29), 11896-11899 (2011). DOI: 10.1073/pnas.1105112108 Cited 56 times

Nataliya Nady, Alexander Lemak, John R. Walker, George V. Avvakumov, Michael S. Kareta, Mayada Achour, Sheng Xue, Shili Duan, Abdellah Allali-Hassani, Xiaobing Zuo, Yun-Xing Wang, Christian Bronner, Frédéric Chédin, Cheryl H. Arrowsmith, Sirano Dhe-Paganon, "Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein," J. Biol. Chem. 286 (27), 24300-24311 (2011). DOI: 10.1074/jbc.M111.234104 Cited 134 times

Jinjin Zhang, Kimberly A. McCabe, Charles E. Bell, "Crystal structures of [lamda] exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity," Proc. Natl. Acad. Sci. USA 108 (29), 11872-11877 (2011). DOI: 10.1073/pnas.1103467108 Cited 55 times

Chi-Lin Tsai, Jennifer Bridwell-Rabb, David P. Barondeau, "Friedreich’s Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron–Sulfur Cluster Assembly Complex," Biochemistry-US 50 (29), 6478-6487 (2011). DOI: 10.1021/bi200666h Cited 36 times

Shanteri Singh, Aram Chang, Randal D. Goff, Craig A. Bingman, Sabine Grüschow, David H. Sherman, George N. Phillips, Jr., Jon S. Thorson, "Structural characterization of the mitomycin 7-O-methyltransferase," Proteins 79 (7), 2181-2188 (2011). DOI: 10.1002/prot.23040 Cited 17 times

Tsuyoshi Imasaki, Guillermo Calero, Gang Cai, Kuang-Lei Tsai, Kentaro Yamada, Francesco Cardelli, Hediye Erdjument-Bromage, Paul Tempst, Imre Berger, Guy Lorch Kornberg, Francisco J. Asturias, Roger D. Kornberg, Yuichiro Takagi, "Architecture of the Mediator head module," Nature 475, 240-243 (2011). DOI: 10.1038/nature10162 Cited 88 times

E. Bridie Day, Carole Guillonneau, Stephanie Gras, Nicole L. La Gruta, Dario A.A. Vignali, Peter C. Doherty, Anthony W. Purcell, Jamie Rossjohn, Stephen J. Turner, "Structural basis for enabling T-cell receptor diversity within biased virus-specific CD[superscript 8+] T-cell responses," Proc. Natl. Acad. Sci. USA 108 (23), 9536-9541 (2011). DOI: 10.1073/pnas.1106851108 Cited 31 times

Kyle T. Dolan, Erica M. Duguid, Chuan He, "Crystal Structures of SlyA Protein, a Master Virulence Regulator of Salmonella, in Free and DNA-bound States," J. Biol. Chem. 286 (25), 22178-22185 (2011). DOI: 10.1074/jbc.M111.245258 Cited 62 times

Minlong Shi, Jianghai Zhu, Rui Wang, Xing Chen, Lizhi Mi, Thomas Walz, Timothy A. Springer, "Latent TGF-[beta] structure and activation," Nature 474, 343-349 (2011). DOI: 10.1038/nature10152 Cited 582 times

Natallia Strushkevich, Farrell MacKenzie, Tatyana Cherkesova, Irina Grabovec, Sergey Usanov, Hee-Won Park, "Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system," Proc. Natl. Acad. Sci. USA 108 (25), 10139-10143 (2011). DOI: 10.1073/pnas.1019441108 Cited 178 times

Pavel Plevka, Bärbel Kaufmann, Michael G. Rossmann, "Analysis of phases in the structure determination of an icosahedral virus," Acta Crystallogr. D 67 (6), 568-577 (2011). DOI: 10.1107/S090744491101448X Cited 6 times

Yi Liu, Feng Wang, Pingwei Li, Xiangshi Tan, "Insights into the Mechanistic Role of the [Fe[subscript 4]S[subscript 4]] Cubane in the A-Cluster {[Fe[subscript 4]S[subscript 4]]-(SR)-[Ni[subscript p]Ni[subscript d]]} of Acetyl-Coenzyme A Synthase," ChemBioChem 12 (9), 1417-1421 (2011). DOI: 10.1002/cbic.201100101

Jiusheng Lin, Mark A. Wilson, "Escherichia coli Thioredoxin-like Protein YbbN Contains an Atypical Tetratricopeptide Repeat Motif and Is a Negative Regulator of GroEL," J. Biol. Chem. 286 (22), 19459-19469 (2011). DOI: 10.1074/jbc.M111.238741 Cited 9 times

Michael L. Oldham, Jue Chen, "Crystal Structure of the Maltose Transporter in a Pretranslocation Intermediate State," Science 332, 1202-1205 (2011). DOI: 10.1126/science.1200767 Cited 168 times

Jonathan R. Whicher, Galina Florova, Paulina K. Sydor, Renu Singh, Mamoun Alhamadsheh, Gregory L. Challis, Kevin A. Reynolds, Janet L. Smith, "Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor," J. Biol. Chem. 286 (25), 22558-22569 (2011). DOI: 10.1074/jbc.M110.213512 Cited 34 times

Kunio S. Misono, John S. Philo, Tsutomu Arakawa, Craig M. Ogata, Yue Qiu, Haruo Ogawa, Howard S. Young, "Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase," FEBS J. 278 (11), 1818-1829 (2011). DOI: 10.1111/j.1742-4658.2011.08083.x Cited 61 times

Heather R. Brodkin, Walter R.P. Novak, Amy C. Milne, J. Alejandro D’Aquino, N.M. Karabacak, Ilana G. Goldberg, Jeffrey N. Agar, Mark S. Payne, Gregory A. Petsko, Mary Jo Ondrechen, Dagmar Ringe, "Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida," Biochemistry-US 50 (22), 4923-4935 (2011). DOI: 10.1021/bi101761e Cited 36 times

Wenjun Cui, Jingzhi Li, David Ron, Bingdong Sha, "The structure of the PERK kinase domain suggests the mechanism for its activation," Acta Crystallogr. D 67 (5), 423-428 (2011). DOI: 10.1107/S0907444911006445 Cited 81 times

Louis M. Lazar, S. Zoe Fisher, Aaron G. Moulin, Andrey Kovalevsky, Walter R.P. Novak, Paul Langan, Gregory A. Petsko, Dagmar Ringe, "Time-of-flight neutron diffraction study of bovine [gamma]-chymotrypsin at the Protein Crystallography Station," Acta Crystallogr. F 67 (5), 587-590 (2011). DOI: 10.1107/S1744309111009341 Cited 1 times

Rui Xu, Ian A. Wilson, "Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin," J. Virol. 85 (10), 5172-5182 (2011). DOI: 10.1128/JVI.02430-10 Cited 98 times

Alexei S. Soares, Matthew A. Engel, Richard Stearns, Sammy Datwani, Joe Olechno, Richard Ellson, John M. Skinner, Marc Allaire, Allen M. Orville, "Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures," Biochemistry-US 50 (21), 4399-4401 (2011). DOI: 10.1021/bi200549x Cited 34 times

L. Makowski, J. Bardhan, D. Gore, J. Lal, S. Mandava, S. Park, D.J. Rodi, N.T. Ho, C. Ho, R.F. Fischetti, "WAXS Studies of the Structural Diversity of Hemoglobin in Solution," J. Mol. Biol. 408 (5), 909-921 (2011). DOI: 10.1016/j.jmb.2011.02.062 Cited 22 times

Qun Wan, Md Faiz Ahmad, James Fairman, Bonnie Gorzelle, María de la Fuente, Chris Dealwis, Michael E. Maguire, "X-Ray Crystallography and Isothermal Titration Calorimetry Studies of the Salmonella Zinc Transporter ZntB," Structure 19 (5), 700-710 (2011). DOI: 10.1016/j.str.2011.02.011 Cited 24 times

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Arulandu Arockiasamy, Anup Aggarwal, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site," Protein Sci. 20 (5), 827-833 (2011). DOI: 10.1002/pro.607 Cited 7 times

Brett Spurrier, Jared M. Sampson, Maxim Totrov, Huiguang Li, Timothy O'Neal, Constance Williams, James Robinson, Miroslaw K. Gorny, Susan Zolla-Pazner, Xiang-Peng Kong, "Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120," Structure 19 (5), 691-699 (2011). DOI: 10.1016/j.str.2011.02.012 Cited 20 times

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Robert N. Kirchdoerfer, Amanda L. Garner, Caralyn E. Flack, Jenny M. Mee, Alexander R. Horswill, Kim D. Janda, Gunnar F. Kaufmann, Ian A. Wilson, "Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody," J. Biol. Chem. 286 (19), 17351-17358 (2011). DOI: 10.1074/jbc.M111.231258 Cited 39 times

Amie K. Boal, Tyler L. Grove, Monica I. McLaughlin, Neela H. Yennawar, Squire J. Booker, Amy C. Rosenzweig, "Structural Basis for Methyl Transfer by a Radical SAM Enzyme," Science 332, 1089-1092 (2011). DOI: 10.1126/science.1205358 Cited 124 times

E. Sethe Burgie, Craig A. Bingman, Shin-ichi Makino, Gary E. Wesenberg, Xiaokang Pan, Brian G. Fox, George N. Phillips, Jr., "Structural architecture of Galdieria sulphuraria DCN1L," Proteins 79 (4), 1329-1336 (2011). DOI: 10.1002/prot.22937 Cited 3 times

Ruslan Sanishvili, Derek W. Yoder, Sudhir Babu Pothineni, Gerd Rosenbaum, Shenglan Xu, Stefan Vogt, Sergey Stepanov, Oleg A. Makarov, Stephen Corcoran, Richard Benn, Venugopalan Nagarajan, Janet L. Smith, Robert F. Fischetti, "Radiation damage in protein crystals is reduced with a micron-sized X-ray beam," Proc. Natl. Acad. Sci. USA 108 (15), 6127 -6132 (2011). DOI: 10.1073/pnas.1017701108 Cited 92 times

Chen Chen, Natalia Gorlatova, Zvi Kelman, Osnat Herzberg, "Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements," Proc. Natl. Acad. Sci. USA 108 (16), 6456-6461 (2011). DOI: 10.1073/pnas.1013657108 Cited 38 times

Farisa Syeda, Rebecca L. Fagan, Matthew Wean, George V. Avvakumov, John R. Walker, Sheng Xue, Sirano Dhe-Paganon, Charles Brenner, "The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1," J. Biol. Chem. 286 (17), 15344-15351 (2011). DOI: 10.1074/jbc.M110.209882 Cited 78 times

Fei Xu, Huixian Wu, Vsevolod Katritch, Gye Won Han, Kenneth A. Jacobson, Zhan-Guo Gao, Vadim Cherezov, Raymond C. Stevens, "Structure of an Agonist-Bound Human A[subscript 2A] Adenosine Receptor," Science 332, 322-327 (2011). DOI: 10.1126/science.1202793 Cited 628 times

Narayanan Veeraraghavan, Abir Ganguly, Jui-Hui Chen, Philip C. Bevilacqua, Sharon Hammes-Schiffer, Barbara L. Golden, "Metal Binding Motif in the Active Site of the HDV Ribozyme Binds Divalent and Monovalent Ions," Biochemistry-US 50 (13), 2672-2682 (2011). DOI: 10.1021/bi2000164 Cited 47 times

Kayode K. Ojo, Tracy L. Arakaki, Alberto J. Napuli, Krishna K. Inampudi, Katelyn R. Keyloun, Li Zhang, Wim G.J. Hol, Christophe L.M.J. Verlind, Ethan A. Merritt, Wesley C. Van Voorhis, "Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure–activity relationships with Trypanosoma brucei GSK-3," Mol. Biochem. Parasit. 176 (2), 98-108 (2011). DOI: 10.1016/j.molbiopara.2010.12.009 Cited 26 times

Erik T. Yukl, Brandon R. Goblirsch, Victor L. Davidson, Carrie M. Wilmot, "Crystal Structures of CO and NO Adducts of MauG in Complex with Pre-Methylamine Dehydrogenase: Implications for the Mechanism of Dioxygen Activation," Biochemistry-US 50 (14), 2931-2938 (2011). DOI: 10.1021/bi200023n Cited 18 times

Gira Bhabha, Jeeyeon Lee, Damian C. Ekiert, Jongsik Gam, Ian A. Wilson, H. Jane Dyson, Stephen J. Benkovic, Peter E. Wright, "A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis," Science 332, 234-238 (2011). DOI: 10.1126/science.1198542 Cited 333 times

Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel, Jason N. Cole, John E. Johnson, Victor Nizet, Partho Ghosh, "Streptococcal M1 protein constructs a pathological host fibrinogen network," Nature 472, 64-68 (2011). DOI: 10.1038/nature09967 Cited 71 times

Nicole Hfer, David Aragao, Joseph A. Lyons, Martin Caffrey, "Membrane Protein Crystallization in Lipidic Mesophases. Hosting Lipid Effects on the Crystallization and Structure of a Transmembrane Peptide," Cryst. Growth Des. 11 (4), 1182-1192 (2011). DOI: 10.1021/cg101384p Cited 18 times

Jennifer J. Gehret, Liangcai Gu, William H. Gerwick, Peter Wipf, David H. Sherman, Janet L. Smith, "Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: Structure of a Decarboxylating Thioesterase," J. Biol. Chem. 286 (16), 14445-14454 (2011). DOI: 10.1074/jbc.M110.214635 Cited 49 times

Eliana Gonzales-Vigil, Christopher M. Bianchetti, George N. Phillips, Jr., Gregg A. Howe, "Adaptive evolution of threonine deaminase in plant defense against insect herbivores," Proc. Natl. Acad. Sci. USA 108 (14), 5897-5902 (2011). DOI: 10.1073/pnas.1016157108 Cited 56 times

Hozefa S. Bandukwala, Yongqing Wu, Markus Feuerer, Yongheng Chen, Bianca Barboza, Srimoyee Ghosh, James C. Stroud, Christophe Benoist, Diane Mathis, Anjana Rao, Lin Chen, "Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells," Immunity 34 (4), 479-491 (2011). DOI: 10.1016/j.immuni.2011.02.017 Cited 99 times

Ye Xiang, Michael G. Rossmann, "Structure of bacteriophage [phi]29 head fibers has a supercoiled triple repeating helix-turn-helix motif," Proc. Natl. Acad. Sci. USA 108 (12), 4806-4810 (2011). DOI: 10.1073/pnas.1018097108 Cited 23 times

Vanja Avdic, Pamela Zhang, Sylvain Lanouette, Anastassia Voronova, Ilona Skerjanc, Jean-Francois Couture, "Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic," FASEB J. 25 (3), 960-967 (2011). DOI: 10.1096/fj.10-171959 Cited 13 times

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James Wesley Fairman, Sanath Ranjan Wijerathna, Md Faiz Ahmad, Hai Xu, Ryo Nakano, Shalini Jha, Jay Prendergast, R. Martin Welin, Susanne Flodin, Annette Roos, Pär Nordlund, Zongli Li, Thomas Walz, Chris Godfrey Dealwis, "Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization," Nat. Struct. Mol. Biol. 18 (3), 316-322 (2011). DOI: 10.1038/nsmb.2007 Cited 109 times

Aram Chang, Shanteri Singh, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr, "Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway," Acta Crystallogr. D 67 (3), 197-203 (2011). DOI: 10.1107/S090744491100360X Cited 11 times

Nicholas Noinaj, James W. Fairman, Susan K. Buchanan, "The Crystal Structure of BamB Suggests Interactions with BamA and Its Role within the BAM Complex," J. Mol. Biol. 407 (2), 248-260 (2011). DOI: 10.1016/j.jmb.2011.01.042 Cited 70 times

Shoucheng Du, Laurie Betts, Ruifeng Yang, Haibin Shi, Jason Concel, Jinwoo Ahn, Christopher Aiken, Peijun Zhang, Joanne I. Yeh, "Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding," J. Mol. Biol. 406 (3), 371-386 (2011). DOI: 10.1016/j.jmb.2010.11.027 Cited 41 times

Jia Sun, Yuting Yang, Ke Wan, Ninghui Mao, Tai-Yuan Yu, Yi-Chien Lin, Diane C. DeZwaan, Brian C. Freeman, Jing-Jer Lin, Neal F. Lue, Ming Lei, "Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase [alpha]," Cell Res. 21, 258-274 (2011). DOI: 10.1038/cr.2010.138 Cited 54 times

Jianyu Zhu, Andrei Korostelev, David A. Costantino, John P. Donohue, Harry F. Noller, Jeffrey S. Kieft, "Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome," Proc. Natl. Acad. Sci. USA 108 (5), 1839-1844 (2011). DOI: 10.1073/pnas.1018582108 Cited 32 times

Jens C. Krause, Damian C. Ekiert, Terrence M. Tumpey, Patricia B. Smith, Ian A. Wilson, James E. Crowe, Jr., "An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody," Microbiology 2 (1), e00345-1-e00345-10 (2011). DOI: 10.1128/mBio.00345-10 Cited 37 times

Dianfan Li, Jean Lee, Martin Caffrey, "Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen," Cryst. Growth Des. 11 (2), 530-537 (2011). DOI: 10.1021/cg101378s Cited 40 times

Jerome Wielens, Stephen J. Headey, John J. Deadman, David I. Rhodes, Michael W. Parker, David K. Chalmers, Martin J. Scanlon, "Fragment-Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1," ChemMedChem 6 (2), 258-261 (2011). DOI: 10.1002/cmdc.201000483 Cited 27 times

Petra Verdino, Deborah A. Witherden, M. Sharon Ferguson, Adam L. Corper, Andre Schiefner, Wendy L. Havran, Ian A. Wilson, "Molecular Insights into [gamma delta] T Cell Costimulation by an Anti-JAML Antibody," Structure 19 (1), 80-89 (2011). DOI: 10.1016/j.str.2010.10.007 Cited 8 times

Rakesh Joshi, Kwok Ki Ho, Kristen Tenney, Jui-Hui Chen, Barbara L. Golden, Frederick S. Gimble, "Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity," J. Mol. Biol. 405 (1), 185-200 (2011). DOI: 10.1016/j.jmb.2010.10.029 Cited 11 times

David Yin-wei Lin, Jianbo Diao, Daoguo Zhou, Jue Chen, "Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7," J. Biol. Chem. 286 (1), 441-449 (2011). DOI: 10.1074/jbc.M110.167643 Cited 56 times

Mehabaw G. Derebe, David B. Sauer, Weizhong Zeng, Amer Alam, Ning Shi, Youxing Jiang, "Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites," Proc. Natl. Acad. Sci. USA 108 (2), 598-602 (2011). DOI: 10.1073/pnas.1013636108 Cited 77 times

Jennifer C. Pai, Jeffrey A. Culver, Jason E. Drury, Rakesh S. Motani, Raquel L. Lieberman, Jennifer A. Maynard, "Conversion of scFv peptide-binding specificity for crystal chaperone development," Protein Eng. Des. Sel. 24 (5), 419-428 (2011). DOI: 10.1093/protein/gzq120 Cited 10 times

John B. Bruning, Ana C. Murillo, Ofelia Chacon, Raúl G. Barletta, James C. Sacchettini, "Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine," Antimicrob. Agents Ch. 55 (1), 291-301 (2011). DOI: 10.1128/AAC.00558-10 Cited 82 times

Sudha Chakrapani, Julio F. Cordero-Morales, Vishwanath Jogini, Albert C. Pan, D. Marien Cortes, Benoît Roux, Eduardo Perozo, "On the structural basis of modal gating behavior in K[superscript +] channels," Nat. Struct. Mol. Biol. 18 (1), 67-74 (2011). DOI: 10.1038/nsmb.1968 Cited 55 times

Mehabaw G. Derebe, Weizhong Zeng, Yang Li, Amer Alam, Youxing Jiang, "Structural studies of ion permeation and Ca[superscript 2+] blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore," Proc. Natl. Acad. Sci. USA 108 (2), 592-597 (2011). DOI: 10.1073/pnas.1013643108 Cited 26 times

X. Edward Zhou, Kelly M. Suino-Powell, Yong Xu, Cee-Wah Chan, Osamu Tanabe, Schoen W. Kruse, Ross Reynolds, James Douglas Engel, H. Eric Xu, "The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor," J. Biol. Chem. 286 (4), 2877-2885 (2011). DOI: 10.1074/jbc.M110.168740 Cited 57 times

Lilia Kaustov, Hui Ouyang, Maria Amaya, Alexander Lemak, Nataliya Nady, Shili Duan, Gregory A. Wasney, Zhihong Li, Masoud Vedadi, Matthieu Schapira, Jinrong Min, Cheryl H. Arrowsmith, "Recognition and Specificity Determinants of the Human Cbx Chromodomains," J. Biol. Chem. 286 (1), 521-529 (2011). DOI: 10.1074/jbc.M110.191411 Cited 189 times

Yong Tang, Marc A. Holbert, Neda Delgoshaie, Hugo Wurtele, Benoît Guillemette, Katrina Meeth, Hua Yuan, Paul Drogaris, Eun-Hye Lee, Chantal Durette, Pierre Thibault, Alain Verreault, Philip A. Cole, Ronen Marmorstein, "Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation," Structure 19 (2), 221-231 (2011). DOI: 10.1016/j.str.2010.12.012 Cited 41 times

Soren G.F. Rasmussen, Hee-Jung Choi, Juan Jose Fung, Els Pardon, Paola Casarosa, Pil Seok Chae, Brian T. DeVree, Daniel M. Rosenbaum, Foon Sun Thian, Tong Sun Kobilka, Andreas Schnapp, Ingo Konetzki, Roger K. Sunahara, Samuel H. Gellman, Alexander Pautsch, Jan Steyaert, William I. Weis, Brian K. Kobilka, "Structure of a nanobody-stabilized active state of the [beta subscript 2] adrenoceptor," Nature 469, 175-180 (2011). DOI: 10.1038/nature09648 Cited 1196 times

Daniel M. Rosenbaum, Cheng Zhang, Joseph A. Lyons, Ralph Holl, David Aragao, Daniel H. Arlow, Soren G.F. Rasmussen, Hee-Jung Choi, Brian T. DeVree, Roger K. Sunahara, Pil Seok Chae, Samuel H. Gellman, Ron O. Dror, David E. Shaw, William I. Weis, Martin Caffrey, Peter Gmeiner, Brian K. Kobilka, "Structure and function of an irreversible agonist-[beta subscript 2] adrenoceptor complex," Nature 469, 236-240 (2011). DOI: 10.1038/nature09665 Cited 611 times

Thomas A. Leonard, Bartosz Rozycki, Layla F. Saidi, Gerhard Hummer, James H. Hurley, "Crystal Structure and Allosteric Activation of Protein Kinase C [beta]II," Cell 144 (1), 55-66 (2011). DOI: 10.1016/j.cell.2010.12.013 Cited 141 times

Diwahar Narasimhan, Mark R. Nance, Daquan Gao, Mei-Chuan Ko, Joanne Macdonald, Patricia Tamburi, Dan Yoon, Donald M. Landry, James H. Woods, Chang-Guo Zhan, John J.G. Tesmer, Roger K. Sunahara, "Structural analysis of thermostabilizing mutations of cocaine esterase," Protein Eng. Des. Sel. 23 (7), 537-547 (2010). DOI: 10.1093/protein/gzq025 Cited 36 times

Andrei Korostelev, Jianyu Zhu, Haruichi Asahara, Harry F. Noller, "Recognition of the amber UAG stop codon by release factor RF1," EMBO J. 29 (15), 2577-2585 (2010). DOI: 10.1038/emboj.2010.139 Cited 80 times

Can Xie, Jianghai Zhu, Xing Chen, Lizhi Mi, Noritaka Nishida, Timothy A. Springer, "Structure of an integrin with an [alpha]I domain, complement receptor type 4," EMBO J. 29, 666-679 (2010). DOI: 10.1038/emboj.2009.367 Cited 121 times

S. Agarwal, D. Hong, N.K. Desai, M. H.Sazinsky, J.M. Argüello, A.C. Rosenzweig, "Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA," Proteins 78 (11), 2450-2458 (2010). DOI: 10.1002/prot.22753 Cited 16 times

Brandon Goblirsch, "Ross A. Gortner Predoctoral Fellowship," (2010).

Lucas J. Bailey, Brian G. Fox, "Toluene 4-Monooxygenase and its Complex with Effector Protein T4moD," Encyclopedia of Inorganic Chemistry, Second Edition, R. Bruce King, eds., Wiley, 2010, online. DOI: 10.1002/9781119951438.eibc0699

D.W. Yoder, R. Sanishvili, S. Vogt, S. Xu, O. Makarov, R. Benn, S. Corcoran, R.F. Fischetti, "One‐Micron Beams for Macromolecular Crystallography at GM∕CA‐CAT," SRI 2009, R. Garrett, I. Gentle, K. Nugent, S. Wilkins, eds., 1234, AIP (2010), 419 - 422. DOI: 10.1063/1.3463229 Cited 8 times

Vadim Cherezov, Enrique Abola, Raymond C. Stevens, "Recent Progress in the Structure Determination of GPCRs, a Membrane Protein Family with High Potential as Pharmaceutical Targets," Membrane Protein Structure Determination , Jean-Jacques Lacapère, eds., Springer, 2010, 141 - 168. DOI: 10.1007/978-1-60761-762-4_8

Shenglan Xu, Oleg Makarov, Rich Benn, Derek W. Yoder, Sergey Stepanov, Michael Becker, Stephen Corcoran, Mark Hilgart, Venugopalan Nagarajan, Craig M. Ogata, Sudhir Pothineni, Ruslan Sanishvili, Janet L. Smith, Robert F. Fischetti, "Micro‐Crystallography Developments at GM∕CA‐CAT at the APS," SRI 2009, R. Garrett, I. Gentle, K. Nugent, S. Wilkins, eds., 1234, AIP (2010), 905 - 908. DOI: 10.1063/1.3463363

Laura B. Sheard, Xu Tan, Haibin Mao, John Withers, Gili Ben-Nissan, Thomas R. Hinds, Yuichi Kobayashi, Fong-Fu Hsu, Michal Sharon, John Browse, Sheng Yang He, Josep Rizo, Gregg A. Howe, Ning Zheng, "Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor," Nature 468, 400-405 (2010). DOI: 10.1038/nature09430 Cited 837 times

Brad L. Pentelute, Kalyaneswar Mandal, Zachary P. Gates, Michael R. Sawaya, Todd O. Yeates, Stephen B.H. Kent, "Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography," Chem. Commun. 46 (43), 8174-8176 (2010). DOI: 10.1039/C0CC03148H Cited 36 times

Hao Chen, Chengqi Yi, Jin Zhang, Wenru Zhang, Zhiyun Ge, Cai-Guang Yang, Chuan He, "Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR," EMBO Rep. 11 (9), 685-690 (2010). DOI: 10.1038/embor.2010.96 Cited 35 times

Khawar Sohail Siddiqui, Anne Poljak, Davide De Francisci, Gea Guerriero, Oliver Pilak, Dominic Burg, Mark J. Raftery, Don M. Parkin, Jill Trewhella, Ricardo Cavicchioli, "A chemically modified [alpha]-amylase with a molten-globule state has entropically driven enhanced thermal stability," Protein Eng. Des. Sel. 23 (10), 769-780 (2010). DOI: 10.1093/protein/gzq051 Cited 28 times

Jingwei Huang, Zan Xu, Die Wang, Craig M. Ogata, Krzysztof Palczewski, Xavier Lee, N. Martin Young, "Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses," Glycobiology 20 (12), 1643-1653 (2010). DOI: 10.1093/glycob/cwq118 Cited 7 times

Mark D. Rosen, Hariharan Venkatesan, Hillary M. Peltier, Scott D. Bembenek, Kimon C. Kanelakis, Lucy X. Zhao, Barry E. Leonard, Frances M. Hocutt, Xiaodong Wu, Heather L. Palomino, Theresa I. Brondstetter, Peter V. Haugh, Laurence Cagnon, Wen Yan, Lisa A. Liotta, Andrew Young, Tara Mirzadegan, Nigel P. Shankley, Terrance D. Barrett, Michael H. Rabinowitz, "Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues," ACS Med. Chem. Lett. 1 (9), 526-529 (2010). DOI: 10.1021/ml100198y Cited 52 times

Jieqing Zhu, Jianghai Zhu, Ana Negri, Davide Provasi, Marta Filizola, Barry S. Coller, Timothy A. Springer, "Closed headpiece of integrin [alpah]IIb[beta]3 and its complex with an [alpha]IIb[beta]3-specific antagonist that does not induce opening," Blood 116 (23), 5050-5059 (2010). DOI: 10.1182/blood-2010-04-281154 Cited 74 times

Fu-Yang Lin, Chia-I Liu, Yi-Liang Liu, Yonghui Zhang, Ke Wang, Wen-Yih Jeng, Tzu-Ping Ko, Rong Cao, Andrew H.-J. Wang, Eric Oldfield, "Mechanism of action and inhibition of dehydrosqualene synthase," Proc. Natl. Acad. Sci. USA 107 (50), 21337-21342 (2010). DOI: 10.1073/pnas.1010907107 Cited 48 times

Virginie Molle, Gulcin Gulten, Catherine Vilchèze, Romain Veyron-Churlet, Isabelle Zanella-Cléon, James C. Sacchettini, William R. Jacobs, Jr, Laurent Kremer, "Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis," Mol. Microbiol. 78 (6), 1591-1605 (2010). DOI: 10.1111/j.1365-2958.2010.07446.x Cited 51 times

Ye Xiang, Ulrich Baxa, Ying Zhang, Alasdair C. Steven, Gentry L. Lewis, James L. Van Etten, Michael G. Rossmann, "Crystal Structure of a Virus-Encoded Putative Glycosyltransferase," J. Virol. 84 (23), 12265-12273 (2010). DOI: 10.1128/JVI.01303-10 Cited 10 times

Louise Scharf, Nan-Sheng Li, Andrew J. Hawk, Diana Garzón, Tejia Zhang, Lisa M. Fox, Allison R. Kazen, Sneha Shah, Esmael J. Haddadian, Jenny E. Gumperz, Alan Saghatelian, José D. Faraldo-Gómez, Stephen C. Meredith, Joseph A. Piccirilli, Erin J. Adams, "The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation," Immunity 33 (6), 853-862 (2010). DOI: 10.1016/j.immuni.2010.11.026 Cited 82 times

Janesh Kumar, Mark L. Mayer, "Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains," J. Mol. Biol. 404 (4), 680-696 (2010). DOI: 10.1016/j.jmb.2010.10.006 Cited 37 times

Markos Koutmos, Omer Kabil, Janet L. Smith, Ruma Banerjee, "Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine [beta]-synthase," Proc. Natl. Acad. Sci. USA 107 (49), 20958-20963 (2010). DOI: 10.1073/pnas.1011448107 Cited 82 times

Katarina Moravcevic, Jeannine M. Mendrola, Karl R. Schmitz, Yu-Hsiu Wang, David Slochower, Paul A. Janmey, Mark A. Lemmon, "Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids," Cell 143 (6), 966-977 (2010). DOI: 10.1016/j.cell.2010.11.028 Cited 118 times

Long Li, Joyce Jose, Ye Xiang, Richard J. Kuhn, Michael G. Rossmann, "Structural changes of envelope proteins during alphavirus fusion," Nature 468, 705-708 (2010). DOI: 10.1038/nature09546 Cited 205 times

Bärbel Kaufmann, Valorie D. Bowman, Yi Li, Jozsef Szelei, Peter J. Waddell, Peter Tijssen, Michael G. Rossmann, "Structure of Penaeus stylirostris Densovirus, a Shrimp Pathogen," J. Virol. 84 (21), 11289-11296 (2010). DOI: 10.1128/JVI.01240-10 Cited 31 times

Samantha J. Hyde, Brian E. Eckenroth, Brian A. Smith, William A. Eberley, Nicholas H. Heintz, Jane E. Jackman, Sylvie Doublié, "tRNA[superscript His] guanylyltransferase (THG1), a unique 3′-5′ nucleotidyl transferase, shares unexpected structural homology with canonical 5′-3′ DNA polymerases," Proc. Natl. Acad. Sci. USA 107 (47), 20305-20310 (2010). DOI: 10.1073/pnas.1010436107 Cited 41 times

Yufeng Tong, Wolfram Tempel, Hui Wang, Kaori Yamada, Limin Shen, Guillermo A. Senisterra, Farrell MacKenzie, Athar H. Chishti, Hee-Won Park, "Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin [alpha]1," Proc. Natl. Acad. Sci. USA 107 (47), 20346-20351 (2010). DOI: 10.1073/pnas.1009008107 Cited 39 times

Beili Wu, Ellen Y.T. Chien, Clifford D. Mol, Gustavo Fenalti, Wei Liu, Vsevolod Katritch, Ruben Abagyan, Alexei Brooun, Peter Wells, F. Christopher Bi, Damon J. Hamel, Peter Kuhn, Tracy M. Handel, Vadim Cherezov, Raymond C. Stevens, "Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists," Science 330, 1066-1071 (2010). DOI: 10.1126/science.1194396 Cited 1357 times

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Junbin Hu, Jingzhi Li, Xinguo Qian, Vlad Denic, Bingdong Sha, "The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion," PLoS One 4 (11), e8061-1-e8061-7 (2009). DOI: 10.1371/journal.pone.0008061 Cited 48 times

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Markos Koutmos, Supratim Datta, Katherine A. Pattridge, Janet L. Smith, Rowena G. Matthews, "Insights into the reactivation of cobalamin-dependent methionine synthase," Proc. Natl. Acad. Sci. USA 106 (44), 18527-18532 (2009). DOI: 10.1073/pnas.0906132106 Cited 50 times

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Amie K. Boal, Amy C. Rosenzweig, "Crystal Structures of Cisplatin Bound to a Human Copper Chaperone," J. Am. Chem. Soc. 131 (40), 14196-14197 (2009). DOI: 10.1021/ja906363t Cited 131 times

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Hyuk-Soo Seo, Yingli Ma, Erik W. Debler, Daniel Wacker, Stephan Kutik, Günter Blobel, André Hoelz, "Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex," Proc. Natl. Acad. Sci. USA 106 (34), 14281-14286 (2009). DOI: 10.1073/pnas.0907453106 Cited 55 times

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I-Mei Yu, Wei Zhang, Heather A. Holdaway, Long Li, Victor A. Kostyuchenko, Paul R. Chipman, Richard J. Kuhn, Michael G. Rossmann, Jue Chen, "Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation," Science 319 (5871), 1834-1837 (2008). DOI: 10.1126/science.1153264 Cited 424 times

Jacky Chi Ki Ngo, Kayla Giang, Sutapa Chakrabarti, Chen-Ting Ma, Nhat Huynh, Jonathan C. Hagopian, Pieter C. Dorrestein, Xiang-Dong Fu, Joseph A. Adams, Gourisankar Ghosh, "A Sliding Docking Interaction Is Essential for Sequential and Processive Phosphorylation of an SR Protein by SRPK1," Mol. Cell 29 (5), 563-576 (2008). DOI: 10.1016/j.molcel.2007.12.017 Cited 84 times

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Johanne Le Coq, Alexander Pavlovsky, Radhika Malik, Ruslan Sanishvili, Chengfu Xu, Ronald E. Viola, "Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue," Biochemistry-US 47 (11), 3484-3492 (2008). DOI: 10.1021/bi702400x Cited 31 times

Kaiser C. Shen, Dorota A. Kuczynska, Irene J. Wu, Beverly H. Murray, Lauren R. Sheckler, Gabby Rudenko, "Regulation of Neurexin 1[beta] Tertiary Structure and Ligand Binding through Alternative Splicing," Structure 16, 422-431 (2008). DOI: 10.1016/j.str.2008.01.005 Cited 41 times

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Andrei Fokine, Konstantin A. Miroshnikov, Mikhail M. Shneider, Vadim V. Mesyanzhinov, Michael G. Rossmann, "Structure of the Bacteriophage [phi]KZ Lytic Transglycosylase gp144," J. Biol. Chem. 283 (11), 7242-7250 (2008). DOI: 10.1074/jbc.M709398200 Cited 43 times

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Yong Chen, Yuting Yang, Megan van Overbeek, Jill R. Donigian, Paul Baciu, Titia de Lange, Ming Lei, "A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins," Science 319 (5866), 1092-1096 (2008). DOI: 10.1126/science.1151804 Cited 184 times

Ralf Jauch, Calista Keow Leng Ng, Kumar Singh Saikatendu, Raymond C. Stevens, Prasanna R. Kolatkar, "Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog," J. Mol. Biol. 376 (3), 758-770 (2008). DOI: 10.1016/j.jmb.2007.11.091 Cited 62 times

Min Guo, Michael Ignatov, Karin Musier-Forsyth, Paul Schimmel, Xiang-Lei Yang, "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation," Proc. Natl. Acad. Sci. USA 105 (7), 2331-2336 (2008). DOI: 10.1073/pnas.0712072105 Cited 69 times

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Margarita Malakhova, Valentina Tereshko, Sung-Young Lee, Ke Yao, Yong-Yeon Cho, Ann Bode, Zigang Dong, "Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2," Nat. Struct. Mol. Biol. 15 (1), 112-113 (2008). DOI: 10.1038/nsmb1347 Cited 37 times

Jianbo Diao, Ying Zhang, Jon M. Huibregtse, Daoguo Zhou, Jue Chen, "Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase," Nat. Struct. Mol. Biol. 15 (1), 65-70 (2008). DOI: 10.1038/nsmb1346 Cited 79 times

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Jason W. Johnston, Nathan P. Coussens, Simon Allen, Jon C.D. Houtman, Keith H. Turner, Anthony Zaleski, S. Ramaswamy, Bradford W. Gibson, Michael A. Apicella, "Characterization of the N-Acetyl-5-neuraminic Acid-binding Site of the Extracytoplasmic Solute Receptor (SiaP) of Nontypeable Haemophilus influenzae Strain 2019," J. Biol. Chem. 283 (2), 855-865 (2008). DOI: 10.1074/jbc.M706603200 Cited 55 times

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Junyu Xiao, Hengchuan Xia, Jiahai Zhou, Ishara F. Azmi, Brian A. Davies, David J. Katzmann, Zhaohui Xu, "Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway," Dev. Cell 14 (1), 37-49 (2008). DOI: 10.1016/j.devcel.2007.10.013 Cited 83 times

Stephen C. Graham, J. Mitchell Guss, "Complexes of mutants of Escherichia coli aminopeptidase P and the tripeptide substrate ValProLeu," Arch. Biochem. Biophys. 469 (2), 200-208 (2008). DOI: 10.1016/j.abb.2007.10.009 Cited 16 times

Jing-Dong Ye, Valentina Tereshko, John K. Frederiksen, Akiko Koide, Frederic A. Fellouse, Sachdev S. Sidhu, Shohei Koide, Anthony A. Kossiakoff, Joseph A. Piccirilli, "Synthetic antibodies for specific recognition and crystallization of structured RNA," Proc. Natl. Acad. Sci. USA 105 (1), 82-87 (2008). DOI: 10.1073/pnas.0709082105 Cited 89 times

Dali Liu, Pei W. Thomas, Jessica Momb, Quyen Q. Hoang, Gregory A. Petsko, Dagmar Ringe, Walter Fast, "Structure and Specificity of a Quorum-Quenching Lactonase (AiiB) from Agrobacterium tumefaciens," Biochemistry-US 46 (42), 11789-11799 (2007). DOI: 10.1021/bi7012849 Cited 72 times

Siyang Sun, Kiran Kondabagil, Petra M. Gentz, Michael G. Rossmann, Venigalla B. Rao, "The Structure of the ATPase that Powers DNA Packaging into Bacteriophage T4 Procapsids," Mol. Cell 25 (6), 943-949 (2007). DOI: 10.1016/j.molcel.2007.02.013 Cited 94 times

R.F. Fischetti, D.W. Yoder, S. Xu, S. Stepanov, O. Makarov, R. Benn, S. Corcoran, W. Diete, M. Schwoerer-Boehing, R. Signorato, L. Schroeder, L. Berman, P.J. Viccaro, J.L. Smith, "Optical Performance of the GM/CA-CAT Canted Undulator Beamlines for Protein Crystallography," American Instutte of Physics, J.-Y. Choi, S. Rah, eds., Synchrotron Radiation Instrumentation (2007), 754 - 757.

Christopher D. Fleming, Carol C. Edwards, Stephen D. Kirby, Donald M. Maxwell, Philip M. Potter, Douglas M. Cerasoli, Matthew R. Redinbo, "Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun," Biochemistry-US 46 (17), 5063-5071 (2007). DOI: 10.1021/bi700246n Cited 53 times

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J. Alejandro D'Aquino, Judith R. Lattimer, Andrew Denninger, Katharine E. D'Aquino, Dagmar Ringe, "Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR," Biochemistry-US 46 (42), 11761-11770 (2007). DOI: 10.1021/bi7007883 Cited 8 times

Jill E. Chrencik, Alexei Brooun, Michael I. Recht, George Nicola, Leila K. Davis, Ruben Abagyan, Hans Widmer, Elena B. Pasquale, Peter Kuhn, "Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition," J. Biol. Chem. 282 (50), 36505-36513 (2007). DOI: 10.1074/jbc.M706340200 Cited 46 times

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Yufeng Tong, Preeti Chugha, Prasanta K. Hota, Rebecca S. Alviani, Mei Li, Wolfram Tempel, Limin Shen, Hee-Won Park, Matthias Buck, "Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain," J. Biol. Chem. 282 (51), 37215-37224 (2007). DOI: 10.1074/jbc.M703800200 Cited 98 times

Christopher M. Bianchetti, Li Yi, Stephen W. Ragsdale, George N. Phillips, Jr., "Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2," J. Biol. Chem. 282 (52), 37624-37631 (2007). DOI: 10.1074/jbc.M707396200 Cited 48 times

Todd W. Geders, Liangcai Gu, Jonathan C. Mowers, Haichuan Liu, William H. Gerwick, Kristina Hakansson, David H. Sherman, Janet L. Smith, "Crystal Structure of the ECH[subscript 2] Catalytic Domain of CurF from Lyngbya majuscula: Insights into a Decarboxylase Involved in Polyketide Chain [beta]-Branching," J. Biol. Chem. 282 (49), 35954-35963 (2007). DOI: 10.1074/jbc.M703921200 Cited 38 times

Koki Makabe, Shude Yan, Valentina Tereshko, Grzegorz Gawlak, Shohei Koide, "[Beta]-strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of [Beta]-strand Pairing," J. Am. Chem. Soc. 129 (47), 14661-14669 (2007). DOI: 10.1021/ja074252c Cited 11 times

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson, Soren G.F. Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Peter Kuhn, William I. Weis, Brian K. Kobilka, Raymond C. Stevens, "High-Resolution Crystal Structure of an Engineered Human [beta subscript 2]-Adrenergic G Protein–Coupled Receptor," Science 318, 1258-1265 (2007). DOI: 10.1126/science.1150577 Cited 2608 times

Daniel M. Rosenbaum, Vadim Cherezov, Michael A. Hanson, Soren G.F. Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Xiao-Jie Yao, William I. Weis, Raymond C. Stevens, Brian K. Kobilka, "GPCR Engineering Yields High-Resolution Structural Insights into [beta subscript 2] Adrenergic Receptor Function," Science 318, 1266-1273 (2007). DOI: 10.1126/science.1150609 Cited 1105 times

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Andrew Robinson, Amy P. Guilfoyle, Stephen J. Harrop, Yan Boucher, H.W. Stokes, Paul M.G. Curmi, Bridget C. Mabbutt, "A putative house-cleaning enzyme encoded within an integron array: 1.8 Å crystal structure defines a new MazG subtype," Mol. Microbiol. 66 (3), 610-621 (2007). DOI: 10.1111/j.1365-2958.2007.05932.x Cited 13 times

Akiko Koide, Valentina Tereshko, Serdar Uysal, Katrina Margalef, Anthony A. Kossiakoff, Shohei Koide, "Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar K[subscript D] of a Single-domain Antibody with a Flat Paratope," J. Mol. Biol. 373 (4), 941-953 (2007). DOI: 10.1016/j.jmb.2007.08.027 Cited 56 times

O.A. Makarov, R. Benn, S. Corcoran, S. Devarapalli, R. Fischetti, M. Hilgart, W.W. Smith, S. Stepanov, S. Xu, "EPICS controlled sample mounting robots at the GM/CA CAT," Nucl. Instrum. Methods A 582 (1), 156-158 (2007). DOI: 10.1016/j.nima.2007.08.096 Cited 5 times

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Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson, Jue Chen, "Crystal structure of a catalytic intermediate of the maltose transporter," Nature 450, 515-521 (2007). DOI: 10.1038/nature06264 Cited 404 times

Xin Liu, Ronen Marmorstein, "Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor," Gene Dev. 21 (21), 2711-2716 (2007). DOI: 10.1101/gad.1590607 Cited 65 times

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Liangcai Gu, Todd W. Geders, Bo Wang, William H. Gerwick, Kristina Hakansson, Janet L. Smith, David H. Sherman, "GNAT-Like Strategy for Polyketide Chain Initiation," Science 318, 970-974 (2007). DOI: 10.1126/science.1148790 Cited 80 times

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Wolfram Tempel, Wael M. Rabeh, Katrina L. Bogan, Peter Belenky, Marzena Wojcik, Heather F. Seidle, Lyudmila Nedyalkova, Tianle Yang, Anthony A. Sauve, Hee-Won Park, Charles Brenner, "Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD[superscript +]," PLoS Biol. 5 (10), e263-1-e263-11 (2007). DOI: 10.1371/journal.pbio.0050263 Cited 97 times

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Karl E. Zahn, Hassan Belrhali, Susan S. Wallace, Sylvie Doublié, "Caught Bending the A-Rule:  Crystal Structures of Translesion DNA Synthesis with a Non-Natural Nucleotide," Biochemistry-US 46 (37), 10551-10561 (2007). DOI: 10.1021/bi7008807 Cited 38 times

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Ying Zhang, Ye Xiang, James L. Van Etten, Michael G. Rossmann, "Structure and Function of a Chlorella Virus-Encoded Glycosyltransferase," Structure 15 (9), 1031-1039 (2007). DOI: 10.1016/j.str.2007.07.006 Cited 18 times

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Manchi C.M. Reddy, Satheesh K. Palaninathan, Nishant D. Shetty, Joshua L. Owen, Misty D. Watson, James C. Sacchettini, "High Resolution Crystal Structures of Mycobacterium tuberculosis Adenosine Kinase: Insights into the Mechanism and Specificity of this Novel Prokaryotic Enzyme," J. Biol. Chem. 282 (37), 27334-27342 (2007). DOI: 10.1074/jbc.M703290200 Cited 31 times

Brian A. Moore, Howard H. Robinson, Zhaohui Xu, "The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst," J. Mol. Biol. 371 (2), 410-421 (2007). DOI: 10.1016/j.jmb.2007.05.018 Cited 57 times

Jean-Francois Couture, Evys Collazo, Patricia A. Ortiz-Tello, Joseph S. Brunzelle, Raymond C. Trievel, "Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase," Nat. Struct. Mol. Biol. 14 (8), 689-695 (2007). DOI: 10.1038/nsmb1273 Cited 205 times

Matthew H. Sazinsky, Benjamin LeMoine, Maria Orofino, Roman Davydov, Krisztina Z. Bencze, Timothy L. Stemmler, Brian M. Hoffman, Jose M. Arguello, Amy C. Rosenzweig, "Characterization and Structure of a Zn[superscript 2+] and [2Fe-2S]-containing Copper Chaperone from Archaeoglobus fulgidus," J. Biol. Chem. 282 (35), 25950-25959 (2007). DOI: 10.1074/jbc.M703311200 Cited 26 times

Scott A. Lujan, Laura M. Guogas, Heather Ragonese, Steven W. Matson, Matthew R. Redinbo, "Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase," Proc. Natl. Acad. Sci. USA 104 (30), 12282-12287 (2007). DOI: 10.1073/pnas.0702760104 Cited 66 times

Debra S. Touw, Christer E. Nordman, Jeanne A. Stuckey, Vincent L. Pecoraro, "Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils," Proc. Natl. Acad. Sci. USA 104 (29), 11969-11974 (2007). DOI: 10.1073/pnas.0701979104 Cited 64 times

Chi-Lin Tsai, Kuppan Gokulan, Pablo Sobrado, James C. Sacchettini, Paul F. Fitzpatrick, "Mechanistic and Structural Studies of H373Q Flavocytochrome b[subscript 2]:  Effects of Mutating the Active Site Base," Biochemistry-US 46 (26), 7844-7851 (2007). DOI: 10.1021/bi7005543 Cited 15 times

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch," J. Virol. 81 (12), 6700-6708 (2007). DOI: 10.1128/JVI.02817-06 Cited 52 times

Sanghamitra Dey, Zhiqin Hu, Xiao Lan Xu, James C. Sacchettini, Gregory A. Grant, "The Effect of Hinge Mutations on Effector Binding and Domain Rotation in Escherichia coli D-3-Phosphoglycerate Dehydrogenase," J. Biol. Chem. 282 (25), 18418-18426 (2007). DOI: 10.1074/jbc.M701174200 Cited 12 times

Erik W. Debler, Gunnar F. Kaufmann, Robert N. Kirchdoerfer, Jenny M. Mee, Kim D. Janda, Ian A. Wilson, "Crystal structures of a quorum-quenching antibody," J. Mol. Biol. 368 (5), 1392-1402 (2007). DOI: 10.1016/j.jmb.2007.02.081 Cited 25 times

Feng Wang, Robert Langley, Gulcin Gulten, Lei Wang, James C. Sacchettini, "Identification of a Type III Thioesterase Reveals the Function of an Operon Crucial for Mtb Virulence," Chem. Biol. 14 (5), 543-551 (2007). DOI: 10.1016/j.chembiol.2007.04.005 Cited 37 times

M. Rossmann, "Fellow of the American Academy of Microbiology," (2007).

Sergey Stepanov, "Transformation of X-ray Server from a set of WWW-accessed programs into WWW-based library for remote calls from X-ray data analysis software," Thin Solid Films 515 (14), 5700-5703 (2007). DOI: 10.1016/j.tsf.2006.12.011 Cited 3 times

Ling Qin, Denise A. Mills, Carrie Hiser, Anna Murphree, R. Michael Garavito, Shelagh Ferguson-Miller, Jonathan Hosler, "Crystallographic Location and Mutational Analysis of Zn and Cd Inhibitory Sites and Role of Lipidic Carboxylates in Rescuing Proton Path Mutants in Cytochrome c Oxidase," Biochemistry-US 46 (21), 6239-6248 (2007). DOI: 10.1021/bi700173w Cited 32 times

Arati Ramesh, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal Structure of Rsr, an Ortholog of the Antigenic Ro Protein, Links Conformational Flexibility to RNA Binding Activity," J. Biol. Chem. 282 (20), 14960-14967 (2007). DOI: 10.1074/jbc.M611163200 Cited 10 times

C. Gerdts, "The Elizabeth R. Norton Prize at the University of Chicago," (2007).

S. Yan, G. Gawlak, K. Makabe, V. Tereshko, A. Koide, S. Koide, "Hydrophobic Surface Burial Is the Major Stability Determinant of a Flat, Single-layer [beta]-Sheet," J. Mol. Biol. 368 (1), 230-243 (2007). DOI: 10.1016/j.jmb.2007.02.003 Cited 18 times

Korin E. Wheeler, Judith M. Nocek, Deborah A. Cull, Liliya A. Yatsunyk, Amy C. Rosenzweig, Brian M. Hoffman, "Dynamic Docking of Cytochrome b[subscript 5] with Myoglobin and [alpha]-Hemoglobin: Heme-Neutralization “Squares” and the Binding of Electron-Transfer-Reactive Configurations," J. Am. Chem. Soc. 129 (13), 3906-3917 (2007). DOI: 10.1021/ja067598g Cited 38 times

Akiko Koide, Ryan N. Gilbreth, Kaori Esaki, Valentina Tereshko, Shohei Koide, "High-affinity single-domain binding proteins with a binary-code interface," Proc. Natl. Acad. Sci. USA 104 (16), 6632-6637 (2007). DOI: 10.1073/pnas.0700149104 Cited 130 times

Mihwa Lee, Megan J. Maher, J. Mitchell Guss, "Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-­fluoroorotate: catalytic activity is reflected by the crystal form," Acta Crystallogr. F 63 (3), 154-161 (2007). DOI: 10.1107/S1744309107004009 Cited 10 times

Sergei P. Boudko, Richard J. Kuhn, Michael G. Rossmann, "The Coiled-coil Domain Structure of the Sin Nombre Virus Nucleocapsid Protein," J. Mol. Biol. 366 (5), 1538-1544 (2007). DOI: 10.1016/j.jmb.2006.12.046 Cited 28 times

Raquel L. Lieberman, Brandon A. Wustman, Pedro Huertas, Allan C. Powe Jr, Corey W. Pine, Richie Khanna, Michael G. Schlossmacher, Dagmar Ringe, Gregory A. Petsko, "Structure of acid [beta]-glucosidase with pharmacological chaperone provides insight into Gaucher disease," Nat. Chem. Biol. 3 (2), 101-107 (2007). DOI: 10.1038/nchembio850 Cited 181 times

N.P. Coussens, J.C. Mowers, C. McDonald, G. Nunez, S. Ramaswamy, "Crystal structure of the Nod1 caspase activation and recruitment domain," Biochem. Biophys. Res. Commun. 353 (1), 1-5 (2007). DOI: 10.1016/j.bbrc.2006.11.122 Cited 48 times

Vladimir Yu. Torbeev, Stephen B.H. Kent, "Convergent Chemical Synthesis and Crystal Structure of a 203 Amino Acid 'Covalent Dimer' HIV-1 Protease Enzyme Molecule," Angew. Chem. Int. Ed. 43 (10), 1667-1670 (2007). DOI: 10.1002/anie.200604087 Cited 133 times

Feng Wang, Elaine R. Podell, Arthur J. Zaug, Yuting Yang, Paul Baciu, Thomas R. Cech, Ming Lei, "The POT1–TPP1 telomere complex is a telomerase processivity factor," Nature 445, 506-510 (2007). DOI: 10.1038/nature05454 Cited 487 times

S. Ferguson-Miller, "American Association for the Advancement of Science," (2007).

Feng Wang, Robert Langley, Gulcin Gulten, Lynn G. Dover, Gurdyal S. Besra, William R. Jacobs, Jr., James C. Sacchettini, "Mechanism of thioamide drug action against tuberculosis and leprosy," J. Exp. Med. 204 (1), 73-78 (2007). DOI: 10.1084/jem.20062100 Cited 185 times

Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, Sylvie Doublie´, "A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol," Proc. Natl. Acad. Sci. USA 104 (3), 814-818 (2007). DOI: 10.1073/pnas.0606648104 Cited 78 times

Consuelo Garcia-Rodriguez, Raphael Levy, Joseph W. Arndt, Charles M. Forsyth, Ali Razai, Jianlong Lou, Isin Geren, Raymond C. Stevens, James D. Marks, "Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin," Nat. Biotechnol. 25 (1), 107-116 (2007). DOI: 10.1038/nbt1269 Cited 134 times

Matthew Hogg, Pierre Aller, William Konigsberg, Susan S. Wallace, Sylvie Doublie, "Structural and Biochemical Investigation of the Role in Proofreading of a [beta] Hairpin Loop Found in the Exonuclease Domain of a Replicative DNA Polymerase of the B Family," J. Biol. Chem. 282 (2), 1432-1444 (2007). DOI: 10.1074/jbc.M605675200 Cited 55 times

Eduard Bitto, Craig A. Bingman, Gary E. Wesenberg, Jason G. McCoy, George N. Phillips, Jr., "Structure of aspartoacylase, the brain enzyme impaired in Canavan disease," Proc. Natl. Acad. Sci. USA 104 (2), 456-461 (2007). DOI: 10.1073/pnas.0607817104 Cited 50 times

Koki Makabe, Valentina Tereshko, Grzegorz Gawlak, Shude Yan, Shohei Koide, "Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering," Protein Sci. 15, 1907-1914 (2006). DOI: 10.1110/ps.062246706 Cited 32 times

Y. Xiang, M.C. Morais, A.J. Battisti, S. Grimes, P.J. Jardine, D.L. Anderson, M.G. Rossmann, "Structural changes of bacteriophage [phi]29 upon DNA packaging and release," EMBO J. 25, 5229-5239 (2006). DOI: 10.1038/sj.emboj.7601386 Cited 96 times

Catherine Vilchèze, Feng Wang, Masayoshi Arai, Manzour Hernando Hazbón, Roberto Colangeli, Laurent Kremer, Torin R. Weisbrod, David Alland, James C. Sacchettini, William R . Jacobs, Jr, "Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid," Nat. Med. 12, 1027-1029 (2006). DOI: 10.1038/nm1466 Cited 219 times

Cory J. Gerdts, Valentina Tereshko, Maneesh K. Yadav, Irina Dementieva, Frank Collart, Andrzej Joachimiak, Raymond C. Stevens, Peter Kuhn, Anthony Kossiakoff, Rustem F. Ismagilov, "Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization," Angew. Chem. Int. Ed. 45 (48), 8156-8160 (2006). DOI: 10.1002/anie.200602946 Cited 104 times

Quansheng Liu, Jaclyn C. Greimann, Christopher D. Lima, "Reconstitution, Activities, and Structure of the Eukaryotic RNA Exosome," Cell 127 (6), 1223-1237 (2006). DOI: 10.1016/j.cell.2006.10.037 Cited 394 times

Liang Li, Debarshi Mustafi, Qiang Fu, Valentina Tereshko, Delai L. Chen, Joshua D. Tice, Rustem F. Ismagilov, "Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins," Proc. Natl. Acad. Sci. USA 103 (51), 19243-19248 (2006). DOI: 10.1073/pnas.0607502103 Cited 93 times

Lu Gan, Jeffrey A. Speir, James F. Conway, Gabriel Lander, Naiqian Cheng, Brian A. Firek, Roger W. Hendrix, Robert L. Duda, Lars Liljas, John E. Johnson, "Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM," Structure 14 (11), 1655-1665 (2006). DOI: 10.1016/j.str.2006.09.006 Cited 56 times

Koki Makabe, Dan McElheny, Valentia Tereshko, Aaron Hilyard, Grzegorz Gawlak, Shude Yan, Akiko Koide, Shohei Koide, "Atomic structures of peptide self-assembly mimics," Proc. Natl. Acad. Sci. USA 103 (47), 17753-17758 (2006). DOI: 10.1073/pnas.0606690103 Cited 49 times

Peng R. Chen, Taeok Bae, Wade A. Williams, Erica M. Duguid, Phoebe A. Rice, Olaf Schneewind, Chuan He, "An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus," Nat. Chem. Biol. 2 (11), 591-595 (2006). DOI: 10.1038/nchembio820 Cited 151 times

Susan J. Gagnon, Oleg Y. Borbulevych, Rebecca L. Davis-Harrison, Richard V. Turner, Marale Damirjian, Alison Wojnarowicz, William E. Biddison, Brian M. Baker, "T Cell Receptor Recognition via Cooperative Conformational Plasticity," J. Mol. Biol. 363 (1), 228-243 (2006). DOI: 10.1016/j.jmb.2006.08.045 Cited 57 times

S.G. Podorov, N.N. Faleev, K.M. Pavlov, D.M. Paganin, S.A. Stepanov, E. Förster, "A new approach to wide-angle dynamical X-ray diffraction by deformed crystals," J. Appl. Crystallogr. 39 (5), 652-655 (2006). DOI: 10.1107/S0021889806025696 Cited 15 times

John W. Giraldes, David L. Akey, Jeffrey D. Kittendorf, David H. Sherman, Janet L. Smith, Robert A. Fecik, "Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels," Nat. Chem. Biol. 2 (10), 531-536 (2006). DOI: 10.1038/nchembio822 Cited 72 times

Ling Qin, Carrie Hiser, Anne Mulichak, R. Michael Garavito, Shelagh Ferguson-Miller, "Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase," Proc. Natl. Acad. Sci. USA 103 (44), 16117-16122 (2006). DOI: 10.1073/pnas.0606149103 Cited 232 times

David L. Akey, Jeffrey D. Kittendorf, John W. Giraldes, Robert A. Fecik, David H. Sherman, Janet L. Smith, "Structural basis for macrolactonization by the pikromycin thioesterase," Nat. Chem. Biol. 2 (10), 537-542 (2006). DOI: 10.1038/nchembio824 Cited 93 times

Yong Chen, Yuting Yang, Feng Wang, Ke Wan, Kenichi Yamane, Yi Zhang, Ming Lei, "Crystal structure of human histone lysine-specific demethylase 1 (LSD1)," Proc. Natl. Acad. Sci. USA 103 (38), 13956-13961 (2006). DOI: 10.1073/pnas.0606381103 Cited 179 times

Jill E. Chrencik, Alexei Brooun, Michelle L. Kraus, Michael I. Recht, Anand R. Kolatkar, Gye Won Han, Jan Marcus Seifert, Hans Widmer, Manfred Auer, Peter Kuhn, "Structural and Biophysical Characterization of the EphB4·EphrinB2 Protein-Protein Interaction and Receptor Specificity," J. Biol. Chem. 281 (38), 28185-28192 (2006). DOI: 10.1074/jbc.M605766200 Cited 72 times

J.G. McCoy, C.A. Bingman, E. Bitto, M.M. Holdorf, C.A. Makaroff, G. N. Phillips Jr., "Structure of an ETHE1-like protein from Arabidopsis thaliana," Acta Crystallogr. D 62 (9), 964-970 (2006). DOI: 10.1107/S0907444906020592 Cited 36 times

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Alexei Brooun, Mark Griffith, Kin Moy, Maneesh K. Yadav, Jeffrey Velasquez, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs," J. Virol. 80 (16), 7894-7901 (2006). DOI: 10.1128/JVI.00467-06 Cited 80 times

Kevin G. Hoff, Jose L. Avalos, Kristin Sens, Cynthia Wolberger, "Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD[superscript +] and Acetylated Peptide," Structure 14 (8), 1231-1240 (2006). DOI: 10.1016/j.str.2006.06.006 Cited 105 times

Matthew H. Sazinsky, Sorabh Agarwal, Jose M. Arguello, Amy C. Rosenzweig, "Structure of the actuator domain from the Archaeoglobus fulgidus Cu[superscript +]-ATPase," Biochemistry-US 45 (33), 9949-9955 (2006). DOI: 10.1021/bi0610045 Cited 54 times

Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis, Dinshaw J. Patel, "Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF," Nature 442, 91-95 (2006). DOI: 10.1038/nature04802 Cited 556 times

Tao Wang, Xiangbin Zhang, Poonam Bheda, Javier R. Revollo, Shin-ichiro Imai, Cynthia Wolberger, "Structure of Nampt/PBEF/visfatin, a mammalian NAD[superscript +]biosynthetic enzyme," Nat. Struct. Mol. Biol. 13 (7), 661-662 (2006). DOI: 10.1038/nsmb1114 Cited 194 times

Kiira Ratia, Kumar Singh Saikatendu, Bernard D. Santarsiero, Naina Barretto, Susan C. Baker, Raymond C. Stevens, Andrew D. Mesecar, "Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme," Proc. Natl. Acad. Sci. USA 103 (15), 5717-5722 (2006). DOI: 10.1073/pnas.0510851103 Cited 258 times

Chittaranjan Das, Quyen Q. Hoang, Cheryl A. Kreinbring, Sarah J. Luchansky, Robin K. Meray, Soumya S. Ray, Peter T. Lansbury, Dagmar Ringe, Gregory A. Petsko, "Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1," Proc. Natl. Acad. Sci. USA 103 (12), 4675-4680 (2006). DOI: 10.1073/pnas.0510403103 Cited 149 times

Jason G. McCoy, Lucas J. Bailey, Eduard Bitto, Craig A. Bingman, David J. Aceti, Brian G. Fox, George N. Phillips Jr., "Structure and mechanism of mouse cysteine dioxygenase," Proc. Natl. Acad. Sci. USA 103 (9), 3084-3089 (2006). DOI: 10.1073/pnas.0509262103 Cited 142 times

I.H. Solomon, J.M. Hager, R. Safi, D.P. McDonnell, M.R. Redinbo, E.A. Ortlund, "Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity," J. Mol. Biol. 354 (5), 1091-1102 (2005). Cited 38 times

Eduard Bitto, Craig A. Bingman, Jason G. McCoy, Simon T.M. Allard, Gary E. Wesenberg, George N. Phillips Jr., "The structure at 1.6 Å resolution of the protein product of the At4g34215 gene from Arabidopsis thaliana," Acta Crystallogr. D 61 (12), 1655-1661 (2005). DOI: 10.1107/S0907444905034074 Cited 12 times

Maneesh K. Yadav, Cory J. Gerdts, Ruslan Sanishvili, Ward W. Smith, L. Spencer Roach, Rustem F. Ismagilov, Peter Kuhn, Raymond C. Stevens, "In situ data collection and structure refinement from microcapillary protein crystallization," J. Appl. Crystallogr. 38 (6), 900-905 (2005). Cited 26 times

Kumar Singh Saikatendu, Jeremiah S. Joseph, Vanitha Subramanian, Tom Clayton, Mark Griffith, Kin Moy, Jeffrey Velasquez, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1´´-Phosphate Dephosphorylation by a Conserved Domain of nsP3," Structure 13, 1665-1675 (2005). DOI: 10.1016/j.str.2005.07.022 Cited 138 times

L. Gan, "Best Poster Award, Molecular Biology/Molecular & Experimental Medicine, Society of Fellows 2005 Fall Poster Symposium," (2005).

Jinhua Wu, Aloke K. Bera, Richard J. Kuhn, Janet L. Smith, "Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing," J. Virol. 79 (16), 10268-10277 (2005). DOI: 10.1128/JVI.79.16.10268-10277.2005 Cited 119 times

J.W. Arndt, W. Yu, F. Bi, R.C. Stevens, "Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition," Biochemistry-US 44 (28), 9574-9580 (2005). DOI: 10.1021/bi0505924 Cited 51 times

Simon T.M. Allard, Craig A. Bingman, Kenneth A. Johnson, Gary E. Wesenberg, Eduard Bitto, WonBae Jeon, George N. Phillips Jr., "Structure at 1.6 Å resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana," Acta Crystallogr. F 61 (7), 647-650 (2005). DOI: 10.1107/S1744309105019743 Cited 10 times

Maneesh K. Yadav, James E. Redman, Luke J. Leman, Julietta M. Alvarez-Gutierrez, Yanming Zhang, C. David Stout, M. Reza Ghadiri, "Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides," Biochemistry-US 44 (28), 9723-9732 (2005). DOI: 10.1021/bi050742a Cited 34 times

S. Xu, R.F. Fischetti, "A Ray-Tracing Study of the Dependence of Focal Properties on Surface Figure Error for a Kirkpatrick-Baez (K-B) Mirror System," American Institute of Physics, 705, AIP (2004), 776 - 779.

Sergey Stepanov, "How to make X-ray simulation software working on WWW: A simple recipe based on seven years of experience," Advances in Computational Methods for X-Ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 165 - 170.

S. Stepanov, "X-ray server: an online resource for simulations of X-ray diffraction and scattering," Advances in Computational Methods for X-ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 16 - 26.

J.T. Collins, C.L. Doose, J.N. Attig, M.M. Baehl, "Canted-undulator front-end exit-mask flow-induced vibration measurements," LS-306, (November -2004).

Jennifer Timm, Klajdi Kosovrasti, Mina Henes, Florian Leidner, Shurong Hou, Akbar Ali, Nese Kurt Yilmaz, Celia A. Schiffer, "Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir," ACS Chem. Biol. 15 (2), 342-352 (2000). DOI: 10.1021/acschembio.9b00675 Cited 3 times


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