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GM/CA @ APS Sponsors:
National Institute of General Medical Sciences (NIGMS) and National Cancer Institute (NCI) of the National Institutes of Health (NIH)

GM/CA @ APS users Brian Kobilka and Robert Lefkowitz won the 2012 Nobel Prize in Chemistry. <a href='news/nobelprize2012.html'>Read more...</a>

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV. Ian Wilson group (Scripps Research Institute) and collaborators <a href='news/2020/IWilson_2020.html'>Read more...</a>

Box mini-beam collimator for user-friendly one-click selection of beam size and improved sample visualization. <a href='facilities/minibeam.html'>Read more...</a>

Aiming for pan-Lassa virus neutralization. Erica Saphire group (La Jolla Institute for Immunology). <a href='news/2019/ESaphire_2019.html'>Read more...</a>

How Fungi Produce Compounds with Potential Pharmaceutical Applications. Janet Smith group (University of Michigan Life Sciences Institute) and collaborators. <a href='https://www.aps.anl.gov/APS-Science-Highlight/2019-09-24/how-fungi-produce-compounds-with-potential-pharmaceutical' target='_blank'>Read more...</a>

Versatile, fast, high capacity (18 puck) automounter, based on the Berkeley Automounter (BAM), is implemented on both GM/CA ID beamlines. <a href='facilities/automounter.html'>Read more...</a>

Structurally distinct active conformations within a GPCR. Matt Whorton group (Oregon Health & Science University). <a href='news/2019/MWhorton_2019.html'>Read more...</a>

Activation of metabotropic glutamate receptors. Brian Kobilka and George Skiniotis groups (Stanford University) and collaborators. <a href='news/2019/BKobilka_2019.html'>Read more...</a>

$Polygon diffraction rastering with JBluIce. <a href='computing/jbluice-epics.html'>Read more...</a>$ Antitumor activity of multispecific frizzled antibodies. Jean-Philippe Julien group (Hospital for Sick Children Research Institute; University of Toronto) and collaborators. <a href='news/2019/JJulien_2019.html'>Read more...</a>

Antitumor activity of multispecific frizzled antibodies. Jean-Philippe Julien group (Hospital for Sick Children Research Institute; University of Toronto) and collaborators. <a href='news/2019/JJulien_2019.html'>Read more...</a>

Topological control of cytokine receptor signaling. Chris Garcia group (Stanford University), David Baker group (University of Washington), and Vijay Sankaran group (Harvard Medical School). <a href='news/2019/KGarcia_2019.html'>Read more...</a>

$Staff displaying the first diffraction pattern with Pilatus3 6M (January, 2014). GM/CA beamlines are equipped with Dectris Eiger-16M and Pilatus3-6M detectors. <a href='facilities/specifications.html'>Read more...</a>$ Structural basis for adhesion G protein-coupled receptor Gpr126 function. Demet Araç group (University of Chicago) and collaborators. <a href='news/2020/DArac_2020.html'>Read more...</a>

Structural basis for adhesion G protein-coupled receptor Gpr126 function. Demet Araç group (University of Chicago) and collaborators. <a href='news/2020/DArac_2020.html'>Read more...</a>

Structurally distinct active conformations within a GPCR. Robert Lefkowitz group (Duke University) and Andrew Kruse group (Harvard Medical School). <a href='news/2020/AKruse_2020_1.html'>Read more...</a>

GM/CA Serial crystallography: using Mylar in situ sandwich plates and 3D-printed holders for room temperature and cryogenic data collection of soluble and membrane protein crystals. <a href='https://www.ncbi.nlm.nih.gov/pubmed/29300389' target='_blank'>Read more...</a>

GM/CA @ APS

The National Institute of General Medical Sciences and National Cancer Institute Structural Biology Facility at the Advanced Photon Source operates a national user facility for structural biology with synchrotron beamlines specializing in intense, tunable micro-beams for crystallography.

IMPORTANT user information during APS restricted operations